Hyphomicrobium sp. MC1: HYPMC_2077
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Entry
HYPMC_2077 CDS
T01557
Symbol
ispDF
Name
(GenBank) IspD/IspF bifunctional enzyme (2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (MEP cytidylyltransferase, MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECPS, MECDP synthase))
KO
K12506
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:
2.7.7.60
4.6.1.12
]
Organism
hmc
Hyphomicrobium sp. MC1
Pathway
hmc00900
Terpenoid backbone biosynthesis
hmc01100
Metabolic pathways
hmc01110
Biosynthesis of secondary metabolites
Module
hmc_M00096
C5 isoprenoid biosynthesis, non-mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
hmc00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
HYPMC_2077 (ispDF)
Enzymes [BR:
hmc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.60 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HYPMC_2077 (ispDF)
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.12 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
HYPMC_2077 (ispDF)
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Motif
Pfam:
YgbB
IspD
NTP_transf_3
CTP_transf_3
Motif
Other DBs
NCBI-ProteinID:
CCB65299
UniProt:
F8JDL8
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All DBs
Position
1971703..1972890
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AA seq
395 aa
AA seq
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MLRIAALIVAAGRGTRAASQGAGPKQYAQIGGKSVLERAIAIFAGHAEIDEVKVVIHADD
GELYRLATSAGGGTKLSEPAMGGATRQASVLRGLEALASSSPPDLVLIHDAARPFVSAKT
ISKVIAALGGRPGALAALPVTDTLKRAADGIVTDTIARDGLWRAQTPQGFHFTPILNAHR
KAAEQGIDTFTDDAAIAEWAGLDVAIVEDLSSNIKITTAEDLDVADRQLTSALEPRIGSG
FDVHRFCEGDHVWLGGIKIPHTHKLEGHSDADVVLHALTDALLGAIGDGDIGQHFPPSDP
KWKGAASKLFLEDAVRRVRDLGGRVGNVDITVLAEAPRVGPHRPAMQELIGGVLGLPAHR
VGIKATTTEQMGFTGRREGIAAMATAMVFLPAETT
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
gtgttgcgcatcgccgctttaatcgtcgcggccggacggggaacgcgcgccgccagccaa
ggcgcgggtccgaaacaatatgctcagattggcggcaaatccgtcctcgaacgggcgatc
gccatcttcgcgggccacgccgagatcgacgaggtcaaagtcgtcattcacgcggatgac
ggtgagttgtatcggcttgcgacctctgccggcggtgggacgaagctttccgaacccgcg
atgggcggcgccacgcggcaggcttcggtccttcggggtcttgaagccctcgcctcctca
tcgccgcccgacctcgttctgatccacgacgcggcgcggccgttcgtttcggctaagacg
atttcgaaggttattgccgcactcggcggacggccaggagcgctggcagctcttcccgtc
accgatacgctgaagcgcgcggccgacggtatcgtgaccgacacaatcgcgcgcgatggt
ctctggcgggcacagacgccgcagggatttcactttacaccgatcctgaacgcgcaccgc
aaagcggccgagcaaggcatcgacacattcaccgacgacgcggcaattgcggaatgggcc
gggctcgacgtagctatcgtcgaagacttaagcagcaacatcaaaatcacgacagcagag
gatctcgacgtggcggaccggcaattgacgagcgcattggaaccgcggatcgggagcggc
tttgacgtgcatcgcttttgcgagggcgatcacgtctggctcggcggcatcaagatcccg
catacacacaagctcgaaggccattcggacgccgacgtcgtattgcacgcattgaccgac
gctttgctcggcgccatcggcgacggcgatatcggtcagcacttcccaccgtccgatccg
aagtggaaaggcgcggcatcgaagctctttcttgaagacgctgttcgacgtgtgcgcgat
cttggcggccgggtaggcaatgtcgatattacggtgctcgccgaagcgccgcgcgtcggt
ccgcatcgcccggccatgcaagagctgatcggtggcgtgctcggacttcccgcacatcgc
gtcggcatcaaagcgacgacgacggagcagatgggcttcaccggacgacgcgaaggcatc
gccgccatggcgactgcgatggtcttcttacccgcggagacaacatga
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