Hylobates moloch (silvery gibbon): 116460777
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Entry
116460777 CDS
T08803
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh04120
Ubiquitin mediated proteolysis
hmh04144
Endocytosis
hmh04330
Notch signaling pathway
hmh04668
TNF signaling pathway
hmh04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
116460777 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
116460777 (ITCH)
04668 TNF signaling pathway
116460777 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
116460777 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
116460777 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hmh04131
]
116460777 (ITCH)
04121 Ubiquitin system [BR:
hmh04121
]
116460777 (ITCH)
Enzymes [BR:
hmh01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
116460777 (ITCH)
Membrane trafficking [BR:
hmh04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
116460777 (ITCH)
Ubiquitin system [BR:
hmh04121
]
Ubiquitin ligases (E3)
HECT type E3
116460777 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
116460777
NCBI-ProteinID:
XP_031997778
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNES
DDPEDAGAGENRRVSGSNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPANTNTNTSEGATSGLIIPLTITGGSGPRPLNPVTQAPLPPGWEQRVDQHGR
VYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYRLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKCILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMLAEWRMSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQITWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctcaccatgaaatcacagctt
cagatcactgtcatctcagcaaaacttaaggaaaataagaagaattggtttggaccaagt
ccttacgtagaggtcacagtagatggacagtcaaagaagacagaaaaatgcaacaacaca
aacagtcccaagtggaagcaaccccttacagttatcgttacccctgtgagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgactttg
cagcttggaggtgacaaagaaccaacagagacaataggagacttgtcaatttgtcttgat
gggctacagttagagtctgaagttgttactaatggtgaaactacatgttcagaaagtgct
tctcagaatgatgatggttccagatccaaggatgaaacaagagtgagcacaaatgaatca
gatgaccccgaagatgcaggagctggtgaaaataggagagtcagtgggagtaattctcca
tcgctctcaaatggtggttttaaaccttctagacctccaagaccttcacgaccaccacca
cccaccccacgtagaccagcatctgtcaatggttcaccatctgccacttctgaaagtgat
gggtctagtacaggctctttgccgccggcaaatacaaatacaaatacatctgaaggagca
acatctggattaataattcctcttactataactggaggctcaggccctaggccattaaat
cctgtaactcaagctcccttgccacctggttgggagcagagagtggaccagcatgggcga
gtttactatgtagatcatgttgagaaaagaacaacatgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacgtggcagaggccaacactggaatccgtccgcaactatgaacaatggcag
ctacagcgtagtcagcttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttatttgctacatcacaaagtaaagaatttgatcctcttggtccattgcca
cccggatgggagaagagaacagacagcaatggcagagtatatttcgtcaaccacaacaca
cgaattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattccgtattttgtggaccacaataga
agaactaccacctatatagatccccgcacaggaaaatctgccctagacaatggacctcag
atagcctatgttcgggacttcaaagcaaaggttcagtatttccggttctggtgtcagcaa
ctggccatgccacagcacataaagattacagtgacaagaaaaacattgtttgaggattcc
tttcaacagataatgagcttcaatccccaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactaccgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgttttatt
ggcagatttattgccatggctctgttccatgggaaattcatagacacaggtttttcttta
ccattctataagtgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaggaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgttgacaaagaaattctaggtgaaattaagagtcatgatctgaaa
cctaatggtggcaatattcttgtaacagaagaaaataaagaggagtacatcagaatgtta
gctgagtggaggatgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcaatatttgcagtactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tatacgaggaccagcaaacaaatcacgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagtaggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggctacccagaagtcatacctgttttaatcgcctggacctgccaccatacaag
agctatgagcaactgaaggaaaagctgttgtttgccatagaagaaacagaaggatttgga
caagagtaa
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