Hylobates moloch (silvery gibbon): 116461800
Help
Entry
116461800 CDS
T08803
Symbol
AKR1C4
Name
(RefSeq) aldo-keto reductase family 1 member C4 isoform X1
KO
K00037
3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:
1.1.1.50
1.1.1.357
1.1.1.225
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00120
Primary bile acid biosynthesis
hmh00140
Steroid hormone biosynthesis
hmh01100
Metabolic pathways
hmh05208
Chemical carcinogenesis - reactive oxygen species
Module
hmh_M00104
Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
hmh_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
116461800 (AKR1C4)
00140 Steroid hormone biosynthesis
116461800 (AKR1C4)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
116461800 (AKR1C4)
Enzymes [BR:
hmh01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
116461800 (AKR1C4)
1.1.1.225 chlordecone reductase
116461800 (AKR1C4)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
116461800 (AKR1C4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aldo_ket_red
Motif
Other DBs
NCBI-GeneID:
116461800
NCBI-ProteinID:
XP_032000016
LinkDB
All DBs
Position
Unknown
AA seq
329 aa
AA seq
DB search
MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEVGFRHIDSAYVYDNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQMVQPALESSLKKLQLDYVDLYLLHFPL
ALKPGETILPKDENGKVIFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGTQRLCISGFPSRMVDPNSPV
LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMK
VLDGLNRNYRYIVMDFLMDHPDYPFSDEY
NT seq
990 nt
NT seq
+upstream
nt +downstream
nt
atggatcccaaatatcagcgtgtggagctaaatgacggtcacttcatgcccgtattggga
tttggcacctatgcacctccagaggttccgaggaacagagctgtggaggtcaccaaatta
gcgatagaagttggcttccgccatattgattctgcttatgtatacgataatgaggagcaa
gttggactggccatccgaagcaagattgcagatggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtgcactttctttcgaccacagatggtccaaccagccttggaa
agctcactgaaaaaacttcaactggactatgttgacctctatcttcttcatttcccattg
gctctcaagccaggtgagacgatactaccaaaagatgaaaatggaaaagtaatattcgac
acagtggatctctgtgccacatgggaggccatggagaagtgtaaagatgcaggattggcc
aagtccattggggtgtccaacttcaaccgcaggcagctggagattatcctcaacaagcca
ggactcaagtacaagcccgtctgcaaccaggtagaatgtcatccttacctcaaccagagc
aaactgctggatttctgcaagtcaaaagacattgttctggttgcctatagtgctctggga
acccaacgactatgcatttctggctttccttccaggatggtggacccgaactccccagtt
cttttggaggacccagttctttgtgccttagcaaagaaacacaaacgaaccccagccctg
attgccctgcgctaccagctgcagcgtggggttgtggtcctggccaagagctacaacgag
cagcggatcagagagaatgtccaggtttttgaattccagttgacatcagaggatatgaaa
gttctagatggcctaaacagaaattatcgatatattgtcatggattttcttatggaccac
cctgattatccattttcagatgaatattag
DBGET
integrated database retrieval system
