Hylobates moloch (silvery gibbon): 116467557 Help Entry 116467557         CDS       T08803                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism hmh  Hylobates moloch (silvery gibbon) Pathway hmh04022   cGMP-PKG signaling pathway hmh04068   FoxO signaling pathway hmh04081   Hormone signaling hmh04140   Autophagy - animal hmh04152   AMPK signaling pathway hmh04211   Longevity regulating pathway hmh04213   Longevity regulating pathway - multiple species hmh04910   Insulin signaling pathway hmh04920   Adipocytokine signaling pathway hmh04923   Regulation of lipolysis in adipocytes hmh04930   Type II diabetes mellitus hmh04931   Insulin resistance hmh04932   Non-alcoholic fatty liver disease hmh04935   Growth hormone synthesis, secretion and action hmh05010   Alzheimer disease hmh05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:hmh00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     116467557 (IRS2)    04022 cGMP-PKG signaling pathway     116467557 (IRS2)    04152 AMPK signaling pathway     116467557 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     116467557 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     116467557 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     116467557 (IRS2)    04923 Regulation of lipolysis in adipocytes     116467557 (IRS2)    04920 Adipocytokine signaling pathway     116467557 (IRS2)    04935 Growth hormone synthesis, secretion and action     116467557 (IRS2)   09149 Aging    04211 Longevity regulating pathway     116467557 (IRS2)    04213 Longevity regulating pathway - multiple species     116467557 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     116467557 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     116467557 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     116467557 (IRS2)    04932 Non-alcoholic fatty liver disease     116467557 (IRS2)    04931 Insulin resistance     116467557 (IRS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N Motif Other DBs NCBI-GeneID:  116467557 NCBI-ProteinID:  XP_032007202 LinkDB All DBs Position Unknown AA seq 1335 aa AA seqDB search MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR VRTASEGDGGAAAGAAAAGARPVSVSGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAVPPAGPAGPAPTSAGGRTFPA SGSGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPD FFSAALHAGGEPLRGVPGCCYSSLPRSYKAPYTCGADSDQYVLMSSPVGRILEEERLEPQ ATPGAGPTQPPHPVVPSPVRPSGGLGGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEY PLPPEPKSPGEYINIDFGESGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSS DSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASPYPPLPPRPSASPSSS LQPPPPPPPPGELYRLPPASAAATAQGPGAASLSSSDTGDNGDYTEMAFGVAATPPQPIA APPKPEAARMASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHS SETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQ PALPAPPLAPQGRPWTPGQPGGLIGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLP PQPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASI DFLSHHLKEATIVKE NT seq 4008 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcacgggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg acggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaagcgggtgatcgcgctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccggagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacttgacaggcgtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctcatgaacatccgccgctgcggccactcggacagcttctttttcatcgaggtgggc cgctcagccgtcacaggccccggcgagctgtggatgcaggcggacgactcggtggtggcg cagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttc cggccgcgcagcaagagccagtcgtcggggtcgtcggccacacaccccatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctgccccctagccagacaggcctggtgcgc cgctcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggggcggcggccgcgggcgcc aggccggtgtcggtgtctgggagccccctgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcagcacagccgctccatgtcaatgcccgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgcccggcccgcacccgcccctgccgcatccgctgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcgggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagcccaggcgacctgcgcgccttctgcagtcaccgaagcaacacg cccgagtcaatcgcagagacgcccccagcccgagacggcggcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgccgggtctcg ggggacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccaca ccggcccggcagcggccggtgccccagccctcctcggcctcgctggatgagtacaccctg atgcgggccaccttctcgggcagcgcgggccgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagacatcgagatcggctcccac aggagctccagcagcaacctgggcgcagacgacggctacatgcccatgacgcccggcgcg gccctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagcccc gccagcgtgtccgcccccaagcagatcttgcaacccagggccgccgccgccgccgccgtg ccccctgcggggcctgcggggccagcgcccacctctgcggggggcaggacattcccggcg agcgggagtggctacaaggccagctcgcccgccgagagctcccccgaggacagtgggtac atgcgcatgtggtgcggctccaagctgtccatggagcatgcagatggcaagctgctgccc aacggggactacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgac ttcttctccgcagccctgcacgccggcggggagccgctcaggggcgttcccggctgctgc tacagctccttgccgcgctcctacaaggccccgtacacctgtggcgcggacagcgaccag tacgtgctcatgagctccccggtggggcgcatcctggaggaggagcggctggagcctcag gccacgccaggggccggccccacgcagccccctcaccccgtagtgccttcgcccgtgcgg cccagcggcggcctaggcggcggccgcccggagggcttcttgggccagcgcggccgggcg gtgcggcccacgcgcctgtccctggaggggctgcccagcctgcccagcatgcacgagtac ccactgccgccggagcccaagagccccggcgagtacatcaacatcgacttcggcgagtcc ggggcccgcctgtcgccgcccgcgcctcccctgctggcgtcggcggcctcgtcctcctcg ctcttgtccgccagcagcccggcctcgtcgctgggctcaggcaccccgggcaccagcagc gacagccggcagcgctctccgctctccgactacatgaacctcgacttcagctcccccaag tctcctaaaccgggcgccccgagcggccaccccgtgggctctttggacggcctcctgtcc cccgaggcctccccgtatccgccgctgcccccgcgtccgtccgcgtccccgtcgtcgtcc ctgcagccgccgccaccgccgccgcccccgggggagctgtaccgcctgccccccgcctcg gccgctgccactgcccagggcccgggcgccgcctcattgtcgtcctcggacaccggggac aatggtgactacaccgagatggcttttggtgtggccgccaccccgccgcaacccatcgcg gcccccccgaagccagaagctgcccgcatggccagcccgacgtcgggcgtgaagaggctg agcctcatggagcaggtgtcaggggtcgaggccttcctgcaggccagccagcccccggac ccccaccgcggcgccaaggtcatccgcgcagacccgcaggggggccgccgccgccacagt tccgagaccttctcctccaccacgacggtcacccccgtgtccccgtccttcgcccacaac cccaagcgccacaactcggcctccgtagaaaatgtctctctcaggaaaagcagcgagggc ggtgtgggtgtcggccctggagggggcgacgagccgcccacctccccccgacagttgcag ccggcgctcccggcgccccctttggcaccgcagggccggccgtggaccccgggtcagccc gggggcttgatcggttgtcctgggagcggtggatcgccaatgcgcagagagacctctgcc ggcttccagaatggtctcaactacatcgccatcgacgtgagggaggagcccgggctgcca ccccagccgcagccgcagccgccgccgccgccgcttcctcagccgggagacaagagctcc tggggtcggacccgaagcctcgggggtctcatcagcgctgtgggcgtcggcagcaccggc ggcgggtgcggggggccgggtcccggtgccctgccccctgccaacacctacgccagcatt gacttcttgtcccaccacttgaaggaggccaccatcgtgaaagagtga

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