KEGG   Hylobates moloch (silvery gibbon): 116472414
Entry
116472414         CDS       T08803                                 
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck
  KO
K05856  lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]
Organism
hmh  Hylobates moloch (silvery gibbon)
Pathway
hmh04064  NF-kappa B signaling pathway
hmh04380  Osteoclast differentiation
hmh04650  Natural killer cell mediated cytotoxicity
hmh04658  Th1 and Th2 cell differentiation
hmh04659  Th17 cell differentiation
hmh04660  T cell receptor signaling pathway
hmh05135  Yersinia infection
hmh05166  Human T-cell leukemia virus 1 infection
hmh05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05340  Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:hmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    116472414 (LCK)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    116472414 (LCK)
   04660 T cell receptor signaling pathway
    116472414 (LCK)
   04658 Th1 and Th2 cell differentiation
    116472414 (LCK)
   04659 Th17 cell differentiation
    116472414 (LCK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116472414 (LCK)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116472414 (LCK)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116472414 (LCK)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    116472414 (LCK)
  09163 Immune disease
   05340 Primary immunodeficiency
    116472414 (LCK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hmh01001]
    116472414 (LCK)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hmh03036]
    116472414 (LCK)
Enzymes [BR:hmh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     116472414 (LCK)
Protein kinases [BR:hmh01001]
 Non-receptor tyrosine kinases
  SRC family
   116472414 (LCK)
Chromosome and associated proteins [BR:hmh03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    116472414 (LCK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 ABC1 Haspin_kinase Kdo
Other DBs
NCBI-GeneID: 116472414
NCBI-ProteinID: XP_058298771
LinkDB
Position
Unknown
AA seq 405 aa
MGPEGSRAGQVRSAGIGGTGAGVRGLIADGCGCAGPGSLGMQQPFVAGREDRRSRSGSFS
LSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPC
QTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA
FLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDM
AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDDEYTAREGAKFPI
KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN
CPEELYQLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq 1218 nt   +upstreamnt  +downstreamnt
atggggccagagggctcccgggctgggcaggtaaggagcgctggtattgggggcacgggc
gccggggtgagaggcctgatagcagatggctgcggctgtgcgggcccaggctccctaggg
atgcagcagccctttgtggctgggagagaagatcgtcgctcaaggtcaggatcgttttca
ctgtccgtccgggacttcgaccagaaccagggagaggtggtgaaacattacaagatccgt
aatctggacaacggtggcttctacatctccccccgaatcacttttcctggcctgcatgaa
ctggtccgccattacaccaatgcttcagatgggctgtgcacacggttgagccgcccctgc
cagacccagaagccccagaagccgtggtgggaggacgagtgggaggttcccagggagacg
ctgaagctggtggagcggctgggggccggacagttcggggaggtgtggatggggtactac
aacgggcacacgaaggtggcggtgaaaagcctgaagcagggcagcatgtccccggatgcc
ttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctggttcggctctac
gctgtggtcacccaggagcccatctacatcatcactgaatacatggagaatgggagtcta
gtggattttctcaagaccccttcaggcatcaagttgaccatcaacaaactcctggacatg
gcagcccaaattgcagaaggcatggcattcattgaagagcggaattatattcatcgtgac
cttcgggctgccaacattctggtgtctgacaccctgagctgcaagattgcagactttggc
ctagcacgcctcattgaggacgacgagtacacagccagggagggggccaagtttcccatt
aagtggacagcgccagaagccattaactacgggacattcaccatcaagtcggatgtgtgg
tcttttgggatcctgctgacggaaattgtcacccatggccgcatcccttacccagggatg
accaacccggaggtgattcagaacctggagcgaggctaccgcatggtgcgccctgacaac
tgtccagaggagctgtaccaactcatgatgctgtgctggaaggagcgcccagaggaccgg
cccacctttgactacctgcgcagcgtgctggaggacttcttcacggccacggagggccag
taccagcctcagccttga

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