Hylobates moloch (silvery gibbon): 116472414
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Entry
116472414 CDS
T08803
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh04064
NF-kappa B signaling pathway
hmh04380
Osteoclast differentiation
hmh04650
Natural killer cell mediated cytotoxicity
hmh04658
Th1 and Th2 cell differentiation
hmh04659
Th17 cell differentiation
hmh04660
T cell receptor signaling pathway
hmh05135
Yersinia infection
hmh05166
Human T-cell leukemia virus 1 infection
hmh05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
116472414 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
116472414 (LCK)
04660 T cell receptor signaling pathway
116472414 (LCK)
04658 Th1 and Th2 cell differentiation
116472414 (LCK)
04659 Th17 cell differentiation
116472414 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
116472414 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116472414 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116472414 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
116472414 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
116472414 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116472414 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hmh03036
]
116472414 (LCK)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116472414 (LCK)
Protein kinases [BR:
hmh01001
]
Non-receptor tyrosine kinases
SRC family
116472414 (LCK)
Chromosome and associated proteins [BR:
hmh03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
116472414 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
ABC1
Haspin_kinase
Kdo
Motif
Other DBs
NCBI-GeneID:
116472414
NCBI-ProteinID:
XP_058298771
LinkDB
All DBs
Position
Unknown
AA seq
405 aa
AA seq
DB search
MGPEGSRAGQVRSAGIGGTGAGVRGLIADGCGCAGPGSLGMQQPFVAGREDRRSRSGSFS
LSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPC
QTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDA
FLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDM
AAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDDEYTAREGAKFPI
KWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDN
CPEELYQLMMLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
atggggccagagggctcccgggctgggcaggtaaggagcgctggtattgggggcacgggc
gccggggtgagaggcctgatagcagatggctgcggctgtgcgggcccaggctccctaggg
atgcagcagccctttgtggctgggagagaagatcgtcgctcaaggtcaggatcgttttca
ctgtccgtccgggacttcgaccagaaccagggagaggtggtgaaacattacaagatccgt
aatctggacaacggtggcttctacatctccccccgaatcacttttcctggcctgcatgaa
ctggtccgccattacaccaatgcttcagatgggctgtgcacacggttgagccgcccctgc
cagacccagaagccccagaagccgtggtgggaggacgagtgggaggttcccagggagacg
ctgaagctggtggagcggctgggggccggacagttcggggaggtgtggatggggtactac
aacgggcacacgaaggtggcggtgaaaagcctgaagcagggcagcatgtccccggatgcc
ttcctggccgaggccaacctcatgaagcagctgcaacaccagcggctggttcggctctac
gctgtggtcacccaggagcccatctacatcatcactgaatacatggagaatgggagtcta
gtggattttctcaagaccccttcaggcatcaagttgaccatcaacaaactcctggacatg
gcagcccaaattgcagaaggcatggcattcattgaagagcggaattatattcatcgtgac
cttcgggctgccaacattctggtgtctgacaccctgagctgcaagattgcagactttggc
ctagcacgcctcattgaggacgacgagtacacagccagggagggggccaagtttcccatt
aagtggacagcgccagaagccattaactacgggacattcaccatcaagtcggatgtgtgg
tcttttgggatcctgctgacggaaattgtcacccatggccgcatcccttacccagggatg
accaacccggaggtgattcagaacctggagcgaggctaccgcatggtgcgccctgacaac
tgtccagaggagctgtaccaactcatgatgctgtgctggaaggagcgcccagaggaccgg
cccacctttgactacctgcgcagcgtgctggaggacttcttcacggccacggagggccag
taccagcctcagccttga
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