Hylobates moloch (silvery gibbon): 116477894
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Entry
116477894 CDS
T08803
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh04014
Ras signaling pathway
hmh04072
Phospholipase D signaling pathway
hmh04148
Efferocytosis
hmh04360
Axon guidance
hmh04625
C-type lectin receptor signaling pathway
hmh04630
JAK-STAT signaling pathway
hmh04650
Natural killer cell mediated cytotoxicity
hmh04660
T cell receptor signaling pathway
hmh04670
Leukocyte transendothelial migration
hmh04722
Neurotrophin signaling pathway
hmh04920
Adipocytokine signaling pathway
hmh04931
Insulin resistance
hmh05168
Herpes simplex virus 1 infection
hmh05205
Proteoglycans in cancer
hmh05208
Chemical carcinogenesis - reactive oxygen species
hmh05211
Renal cell carcinoma
hmh05220
Chronic myeloid leukemia
hmh05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
116477894 (PTPN11)
04630 JAK-STAT signaling pathway
116477894 (PTPN11)
04072 Phospholipase D signaling pathway
116477894 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
116477894 (PTPN11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
116477894 (PTPN11)
04660 T cell receptor signaling pathway
116477894 (PTPN11)
04670 Leukocyte transendothelial migration
116477894 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
116477894 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
116477894 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
116477894 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
116477894 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116477894 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
116477894 (PTPN11)
05211 Renal cell carcinoma
116477894 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
116477894 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hmh01009
]
116477894 (PTPN11)
Enzymes [BR:
hmh01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
116477894 (PTPN11)
Protein phosphatases and associated proteins [BR:
hmh01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
116477894 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
116477894
NCBI-ProteinID:
XP_032024510
LinkDB
All DBs
Position
Unknown
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcactggtgtggaggcagaaaacctactg
ttgacaagaggagttgatggcagttttttggcaaggcctagtaaaagtaaccctggagac
ttcacactttctgttagaagaaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtatggaggggagaaatttgccactttggctgagttggtccagtat
tacatggaacatcacgggcaattaaaagagaagaatggagatgtcattgagcttaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattaactgaaaaaggaaaacatggtagttttcttgtacgagagagc
cagagccaccctggagattttgttctttctgtgcgcactggtgatgacaaaggggagagc
aatgacggcaagtctaaagtgacccatgttatgattcgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgattctttgacagatcttgtggaacattataagaagaat
cctatggtggaaacattgggtacagtactacaactcaagcagccccttaacacgactcgt
ataaatgctgctgaaatagaaagcagagttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacaacaacaggagtgcaaa
cttctctacagccgaaaagagggtcaaaggcaagaaaacaaaaacaaaaatagatataaa
aacatcctgccctttgatcataccagggttgtcctacacgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatatcatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaatgac
ttttggcggatggtgttccaagaaaactcccgagtgattgtcatgacaacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgatgagtatgctctaaaagaatat
ggcgtcatgcgtgttaggaacgtcaaagaaagcgccgctcatgactatacgctaagagaa
cttaaactttcaaaggttggacaagggaatacggagagaacggtctggcaataccacttt
cggacctggccagaccacggagtgcccagcgaccccgggggcgtgctggacttcctggag
gaggtgcaccataagcaggagagcatcatggatgcagggccggttgtggtgcactgcagt
gctggaattggccggacagggacgttcatcgtgattgatattcttattgacatcatcaga
gagaaaggtgttgactgcgacattgacgttcccaaaaccatccagatggtgcggtctcag
aggtcagggatggtccagacagaagcacagtaccgatttatctatatggcggtccagcat
tatattgaaacactacagcgcaggattgaagaagagcagaaaagcaagaggaaagggcat
gaatatacaaatattaagtattctctagcggaccagacgagtggagatcagagccccctc
ccgccttgtactccaacgccaccctgtgcagaaatgagagaagacagtgctagagtctat
gaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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