Hylobates moloch (silvery gibbon): 116810454 Help Entry 116810454         CDS       T08803                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism hmh  Hylobates moloch (silvery gibbon) Pathway hmh01524   Platinum drug resistance hmh04115   p53 signaling pathway hmh04210   Apoptosis hmh04215   Apoptosis - multiple species hmh04217   Necroptosis hmh04620   Toll-like receptor signaling pathway hmh04621   NOD-like receptor signaling pathway hmh04622   RIG-I-like receptor signaling pathway hmh04623   Cytosolic DNA-sensing pathway hmh04625   C-type lectin receptor signaling pathway hmh04657   IL-17 signaling pathway hmh04668   TNF signaling pathway hmh04932   Non-alcoholic fatty liver disease hmh04936   Alcoholic liver disease hmh05010   Alzheimer disease hmh05016   Huntington disease hmh05022   Pathways of neurodegeneration - multiple diseases hmh05132   Salmonella infection hmh05134   Legionellosis hmh05142   Chagas disease hmh05145   Toxoplasmosis hmh05152   Tuberculosis hmh05160   Hepatitis C hmh05161   Hepatitis B hmh05162   Measles hmh05163   Human cytomegalovirus infection hmh05164   Influenza A hmh05165   Human papillomavirus infection hmh05167   Kaposi sarcoma-associated herpesvirus infection hmh05168   Herpes simplex virus 1 infection hmh05169   Epstein-Barr virus infection hmh05170   Human immunodeficiency virus 1 infection hmh05200   Pathways in cancer hmh05203   Viral carcinogenesis hmh05416   Viral myocarditis hmh05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hmh00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     116810454 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     116810454 (CASP8)    04215 Apoptosis - multiple species     116810454 (CASP8)    04217 Necroptosis     116810454 (CASP8)    04115 p53 signaling pathway     116810454 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     116810454 (CASP8)    04621 NOD-like receptor signaling pathway     116810454 (CASP8)    04622 RIG-I-like receptor signaling pathway     116810454 (CASP8)    04623 Cytosolic DNA-sensing pathway     116810454 (CASP8)    04625 C-type lectin receptor signaling pathway     116810454 (CASP8)    04657 IL-17 signaling pathway     116810454 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     116810454 (CASP8)    05203 Viral carcinogenesis     116810454 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     116810454 (CASP8)    05161 Hepatitis B     116810454 (CASP8)    05160 Hepatitis C     116810454 (CASP8)    05164 Influenza A     116810454 (CASP8)    05162 Measles     116810454 (CASP8)    05168 Herpes simplex virus 1 infection     116810454 (CASP8)    05163 Human cytomegalovirus infection     116810454 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     116810454 (CASP8)    05169 Epstein-Barr virus infection     116810454 (CASP8)    05165 Human papillomavirus infection     116810454 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     116810454 (CASP8)    05134 Legionellosis     116810454 (CASP8)    05152 Tuberculosis     116810454 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     116810454 (CASP8)    05142 Chagas disease     116810454 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     116810454 (CASP8)    05016 Huntington disease     116810454 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     116810454 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     116810454 (CASP8)    05416 Viral myocarditis     116810454 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     116810454 (CASP8)    04932 Non-alcoholic fatty liver disease     116810454 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     116810454 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hmh01002]     116810454 (CASP8) Enzymes [BR:hmh01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      116810454 (CASP8) Peptidases and inhibitors [BR:hmh01002]  Cysteine peptidases   Family C14: caspase family    116810454 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  116810454 NCBI-ProteinID:  XP_032610856 LinkDB All DBs Position Unknown AA seq 496 aa AA seqDB search MVPGKGGADYILLPFEKMDFSRNLYDIGEQLGSEDLASLKFLSLDYIPQRKQEPIKDALM LFQRLQEKRMLEESNLSFLKELLFRINRLDLLIAYLNTRKEEMERELQTPGRAQISAYRV MLYQISEEVSRSELKSFKFLLQKEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV CAQINKSLLKIINNYEEFSRERSSSLEGNPDEFSNVEELCGVMTISDSPREQDSESQTLD KVYQMKSKPRGYCLIINNYDFTKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKP HNDCTVQQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGKEAPIYELTSQFTGL KCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQARYIPDEADFLLGM ATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQM PQPTFTLRKKLVFPSD NT seq 1491 nt NT seq  +upstreamnt  +downstreamnt atggtgccaggaaagggtggagcggattatattctcctgccttttgaaaagatggacttc agcagaaatctttatgatattggggaacaactgggcagtgaagatctggcctccctcaag ttcctgagcctggactacattccacaaaggaagcaagaacccatcaaggatgccttgatg ttattccagagactccaggaaaagagaatgttggaggaaagcaatctgtccttcctgaag gagctgctcttccgaattaatagactggatttgctgattgcctacctaaacactagaaag gaggagatggaaagggaacttcagacaccaggcagggctcagatttctgcctacagggtc atgctgtatcagatttcagaagaagtgagcagatcagaattgaagtcttttaagtttctt ttgcaaaaggaaatctccaaatgcaaactggatgatgacatgaacctgctggatattttc atagagatggagaaaagggtcatcctgggagaaggaaagttggacatcctgaaaagagtc tgtgcccaaatcaacaagagcctgctgaagataatcaacaactatgaagaattcagcaga gagagaagcagcagccttgaaggaaatcctgatgaattttcaaatgtggaggagttgtgt ggggtaatgacaatctcggactctccaagagaacaggatagtgaatcacagactttggac aaagtttaccaaatgaaaagcaaacctcgaggatactgtctgatcatcaacaattacgat tttacaaaagcacgggagaaagtgcccaaacttcacagcattagggacaggaatggaaca cacttggatgcaggggctttgaccacgacctttgaagagcttcattttgagatcaagccc cacaatgactgcacagtacagcaaatctatgagattttgaaaatctaccaactcatggac cacagtaacatggactgcttcatctgctgtatcctctcccatggagacaagggcatcatc tacggcactgatggcaaggaggcccccatctatgagctgacatctcagttcactggtttg aagtgcccttcccttgctggaaaacccaaagtgttttttattcaggcttgtcagggggat aactaccagaaaggtatacctgttgagactgattcagaggagcaaccctatttagaaatg gatttatcatcacctcaagcgagatatatcccggatgaggctgactttctgctggggatg gccactgtgaataactgtgtttcctaccgaaatcctgcagagggaacctggtacattcag tcactttgccagagcctgagagagcgatgtcctcgaggtgatgatattctcaccatcctg actgaagtgaactatgaagtaagcaacaaggatgacaagaaaaacatggggaaacagatg ccgcagcctactttcacactaagaaaaaaacttgtcttcccttctgattga

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