Hylobates moloch (silvery gibbon): 116813620
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Entry
116813620 CDS
T08803
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh01522
Endocrine resistance
hmh04012
ErbB signaling pathway
hmh04062
Chemokine signaling pathway
hmh04148
Efferocytosis
hmh04151
PI3K-Akt signaling pathway
hmh04360
Axon guidance
hmh04370
VEGF signaling pathway
hmh04510
Focal adhesion
hmh04517
IgSF CAM signaling
hmh04518
Integrin signaling
hmh04670
Leukocyte transendothelial migration
hmh04810
Regulation of actin cytoskeleton
hmh04935
Growth hormone synthesis, secretion and action
hmh05100
Bacterial invasion of epithelial cells
hmh05135
Yersinia infection
hmh05146
Amoebiasis
hmh05163
Human cytomegalovirus infection
hmh05165
Human papillomavirus infection
hmh05170
Human immunodeficiency virus 1 infection
hmh05200
Pathways in cancer
hmh05202
Transcriptional misregulation in cancer
hmh05205
Proteoglycans in cancer
hmh05208
Chemical carcinogenesis - reactive oxygen species
hmh05222
Small cell lung cancer
hmh05417
Lipid and atherosclerosis
hmh05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
116813620 (PTK2)
04370 VEGF signaling pathway
116813620 (PTK2)
04151 PI3K-Akt signaling pathway
116813620 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
116813620 (PTK2)
04518 Integrin signaling
116813620 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
116813620 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116813620 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
116813620 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
116813620 (PTK2)
04062 Chemokine signaling pathway
116813620 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
116813620 (PTK2)
09158 Development and regeneration
04360 Axon guidance
116813620 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116813620 (PTK2)
05202 Transcriptional misregulation in cancer
116813620 (PTK2)
05205 Proteoglycans in cancer
116813620 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
116813620 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
116813620 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
116813620 (PTK2)
05163 Human cytomegalovirus infection
116813620 (PTK2)
05165 Human papillomavirus infection
116813620 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
116813620 (PTK2)
05100 Bacterial invasion of epithelial cells
116813620 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
116813620 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116813620 (PTK2)
05418 Fluid shear stress and atherosclerosis
116813620 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
116813620 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116813620 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
hmh01009
]
116813620 (PTK2)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116813620 (PTK2)
Protein kinases [BR:
hmh01001
]
Non-receptor tyrosine kinases
FAK family
116813620 (PTK2)
Protein phosphatases and associated proteins [BR:
hmh01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
116813620 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_C_FAK1
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
116813620
NCBI-ProteinID:
XP_032616398
LinkDB
All DBs
Position
Unknown
AA seq
1137 aa
AA seq
DB search
MLLELAGQEALKPAGAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS
STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHDPPSTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES
RRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITA
MAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTALDLRGIGQVLPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAV
IEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLG
ELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag
aaaagcggctgtagtccatttccagtgtgttgggctaaagaatatgacagatacctagca
tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacgccaaattcg
agtactaagactcacctgggtactggtatggaacgttctcctggtgcgatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac
tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg
ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctggaaata
cggcgatcatactgggagatgcggggcaatgcactagaaaagaagtctaactatgaagta
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaacactaagaaaactgatccaacaaacatttagacaatttgccaaccttaataga
gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa
tgcttcaagtgtgctcttggttcaagctggattatttcagtggaactggcaatcggccca
gaagaaggaatcagttacctaacggacaagggctgcaatcccacacatcttgctgacttc
actcaagtgcaaaccattcagtattcaaacagtgaagacaaggacagaaaaggaatgcta
caactaaaaatagcaggtgcacccgagcctctgacagtgacggcaccatccctaaccatt
gcggagaatatggctgacctaatagatgggtactgccggctggtgaatggagcctcgcag
tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcgataccaaagttg
gccaacagcgaaaagcaaggcatgcgaacacacgccgtctctgtgtcaggagtcagtcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgat
cctccttctacggatgaaattagtggggacgaaacagatgattatgctgagattatagat
gaagaagatacttacaccatgccctcaaaaagctatggaatagatgaagccagggattat
gagattcaaagagaaagaatagaacttggacgatgtattggagaaggccaatttggagat
gtacatcaaggcgtttatatgagtccagagaatccagctttggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaagaagccttaacaatg
cgtcagtttgaccatcctcatattgtgaagctgattggagtcatcacagagaatcctgtc
tggataatcatggagctgtgcacacttggagagctgaggtcatttttgcaagtaaggaaa
tacagtttggatctagcatctttgatcctgtatgcctatcagcttagtacagctcttgca
tatctagagagcaaaagatttgtacacagggacattgctgctcggaatgttctggtgtcc
tcaaatgattgtgtaaaattaggagactttggattatcccgatatatggaagatagtact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgacgttttacctcagctagtgacgtatggatgtttggtgtgtgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtaatcggtcgaatt
gaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatg
acgaaatgttgggcctatgaccccagcaggcggcccaggtttactgaacttaaagctcag
ctcagcacaatcctggaggaagagaaggctcagcaagaagagcgcatgaggatggagtcc
agaagacaggccacagtgtcctgggactccggagggtctgatgaagcgccgcccaagcct
agcagaccgggttatcctagtccgaggtccagcgaaggattttatcccagcccacagcac
atggtacaaaccaatcattaccaggtttctggctaccctggttcacatggaatcacagcc
atggctggcagcatctatccaggtcaggcatctcttttggaccaaacagattcatggaat
catagacctcaggagatagcaatgtggcagcccaatgtggaggactctacagcactggac
ctgcgagggattgggcaagtgttgccaactcatctgatggaagagcggctaatccgacag
caacaggaaatggaagaagatcagcgctggctggaaaaagaggaaagatttctgaaacct
gatgtgagactctctcgaggcagtattgacagggaggatggaagtcttcagggtccgatt
ggaaaccaacatatatatcagcctgtgggtaaaccagatcctgcagctccaccaaagaaa
ccgcctcgccctggagctcccggtcatctgggaagccttgccagcctcagcagccctgct
gacagctacaacgagggtgtcaagcttcagccccaggaaatcagcccccctcctactgcc
aacctggaccggtcgaatgataaggtgtatgagaatgtgacgggcctggtgaaagctgtc
atcgagatgtccagtaaaatccagccagccccaccagaggagtacgtccctatggtgaag
gaagtcggcttggccctgaggacgttattggccactgtggatgagaccattcccctccta
ccagccagcacccaccgagagattgagatggcacagaaactattgaactctgacctggga
gagctcatcaacaagatgaaactggcccagcagtatgtcatgaccagcctccagcaagag
tacaaaaagcaaatgctgactgctgctcacgccctggctgtggatgctaaaaacttactc
gatgtcattgaccaagcaagactgaaaatgcttgggcagacgagaccacactga
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integrated database retrieval system
