KEGG   Helicobacter pylori HPAG1: HPAG1_0588
Entry
HPAG1_0588        CDS       T00365                                 
Name
(GenBank) cytoplasmic pump protein of the hefABC efflux system HefC
  KO
K18138  multidrug efflux pump
Organism
hpa  Helicobacter pylori HPAG1
Pathway
hpa01501  beta-Lactam resistance
hpa01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:hpa00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    HPAG1_0588
   01503 Cationic antimicrobial peptide (CAMP) resistance
    HPAG1_0588
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:hpa02000]
    HPAG1_0588
   01504 Antimicrobial resistance genes [BR:hpa01504]
    HPAG1_0588
Transporters [BR:hpa02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   HPAG1_0588
Antimicrobial resistance genes [BR:hpa01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    HPAG1_0588
SSDB
Motif
Pfam: ACR_tran MMPL Patched
Other DBs
NCBI-ProteinID: ABF84655
LinkDB
Position
606139..609225
AA seq 1028 aa
MYKTAINRPITTLMFALAIVFFGTMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK
VTDKIEEAVMGIDGIKKVTSTSSKNVSIVVIEFELEKPNEEALNDVVNKISSVRFDDSNI
KKPSINKFDTDSQAIISLFVSSSSVPATTLNDYAKNTIKPMLQKINGVGGVQLNGFRERQ
IRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNSQRELSILINANSYSVADVEKI
QVGNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANEIEIVDRVYEALKHIQ
AISPSYEIRPFLDTTSYIRTSIEDVKFDLILGAILAVLVVFAFLRNGTITLVSAISIPIS
IMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHKKLEMGMSKRKASYEGVR
EIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIALSYVVVVTIIPMVSSVV
VNPRHSRFYVWSEPFFKALESRYTKLLQWVLNHKLIISIAVVLVFVGSLFVASKIGMEFM
LKEDRGRFLVWLKAKPGVSIDYMTQKSKIFQKAIEKHAEVEFTTLQVGYGTTQNPFKAKI
FVQLKPLKERKKEGELGQFELMSVLRKELRSLPEAKGLDTINLSEVTLIGGGGDSSPFQT
FVFSHSQEAVDKSVENLKKFLLESPELKGKVESYHTSTSESQPQLQLKILRQNANKYGVS
AQTIGSVVSSAFSGTSQASVFKEDGKEYDMIIRVPDDKRVSVEDIKRLQVRNKYDKLMFL
DALVEITETKSPSSISRYNRQRSVTVLAEPNRNAGVSLGEILTQVSKNTKEWLVEGANYR
FTGEADNAKESNGEFLVALATAFVLIYMILAALYESILEPFIIMVTMPLSFSGAFFALGL
VHQPLSMFSMIGLILLIGMVGKNATLLIDVANEERKKGLNIQEAILFAGKTRLRPILMTT
IAMVCGMLPLALASGDGAAMKSPIGIAMSGGLMISMVLSLLIVPVFYRLLAPIDDKIKRF
YQNQKTLE
NT seq 3087 nt   +upstreamnt  +downstreamnt
atgtataaaacagcgattaatcgtcctattacgaccttgatgtttgctttggcgattgtc
ttttttgggactatgggttttaaaaaattgagcgtggcgcttttccctaaaattgatttg
cctacagtggtggttactacgacttatcctggggctagcgctgaaatcatagagagtaag
gtaaccgataagattgaagaagcggtgatggggattgatgggatcaaaaaggttacttct
acgagttctaaaaatgtgagtatcgtcgtcattgaatttgagttagaaaaacctaatgaa
gaagccttaaacgatgtggtgaataaaatttcttcggtgcgttttgatgactccaacatt
aaaaaaccctctatcaataaatttgataccgacagccaagccattatttcattgtttgtg
agcagttcaagcgtgccggctacaacccttaatgactatgctaaaaacaccatcaaaccc
atgctccaaaaaatcaatggggtagggggcgtgcagctcaacggctttagggagcgccag
attaggatttatgccgatcccactttgatgaataaatacaatctgacttatgcggatctt
ttcagcacgcttaaagcggagaatgtggaaattgatggggggcgcattgtcaatagccaa
agggaattgtctattttaattaatgcgaatagttatagcgttgcggatgtagaaaagatc
caagtgggtaatcatgtgcgtcttggcgatattgcaaagattgaaatcggtttggaagaa
gacaacacttttgcgagctttaaagacaaacccggtgtgattttagaaatccaaaagatt
gccggagcgaatgaaattgaaatcgtggatagggtgtatgaagcgttaaaacacattcaa
gccattagccctagctatgaaatcagaccctttttagacaccacgagctacatccgcacc
tctattgaagacgtgaaatttgatctaatcttaggagcgattttagcggttttagtggtg
tttgcgttcttgcgtaacggcacgatcactctcgtttcagcgatctctatccctatttct
atcatggggacttttgcgctcatccaatggatgggcttttcattaaacatgctcaccatg
gtggctttaacgctggcgatagggattatcattgatgatgcgatcgtggtgattgaaaac
atccataaaaagctagaaatgggcatgagtaaacgaaaagcgagctatgagggggtgagg
gaaattggctttgctctagtggcgatttcagcgatgttgctctctgtttttgtgcctata
gggaacatgaaaggcattattgggcgctttttccaaagttttgggatcacggtggcttta
gcgatcgctctctcgtatgtggtggtcgttacgattatccccatggtaagctcagtcgtg
gtcaatcccaggcattctcgtttttatgtgtggagtgagcctttttttaaggctttagag
tctcgttataccaagttactccaatgggtattaaaccacaagctcattatctctatagcg
gtggttttggtgtttgtgggttcgctttttgtggcttctaagatcggtatggagttcatg
ctgaaagaagatagggggaggtttttagtgtggcttaaggctaaaccgggcgtgagcata
gattacatgacacaaaagagtaagatctttcaaaaagcgattgaaaaacatgctgaagtg
gaattcaccaccttgcaagtgggttatggcaccacacaaaacccttttaaggctaagatt
tttgtgcagctcaagcctttaaaagagcgcaaaaaagagggtgaattggggcaatttgag
ttgatgagcgttttaaggaaagagttgagaagcttgcctgaagctaaaggtttagatact
attaatctttctgaagttactcttatagggggcggtggggatagttcgcccttccaaacc
tttgtgttttcccattctcaagaagcggtggataaaagcgtggagaatttgaaaaaattc
ttattagaaagccctgaattaaaaggcaaggttgaaagctatcatacaagcacgagcgaa
tcgcaaccgcaattgcaactcaaaatcttaagacaaaacgctaacaaatacggcgtgagc
gctcaaaccattggatcagtggtgagttctgctttttctgggacttctcaagcgagcgtg
ttcaaagaagatggtaaagaatacgacatgatcattagagtgcctgatgacaagcgcgtt
tctgtagaagacatcaaacgcttgcaagtgcgtaacaaatacgataaattgatgttttta
gacgctttagtggaaatcacagaaactaaaagcccgtctagcatttctcgctataaccgc
caacgcagcgttacggtgcttgctgagcctaataggaatgcgggcgtttctttgggtgag
attttaacgcaagtgagcaaaaacactaaagaatggctggttgaaggggcgaattacaga
tttaccggtgaagcggataacgctaaagagagcaatggggagtttttagtcgctttagcg
acagcgtttgtgctgatttatatgatcttagcggcgttgtatgagtctattttagagcct
tttatcatcatggttaccatgcccttaagcttttcaggggcgttttttgctctgggttta
gtgcatcagcctttgagcatgttctctatgataggcttgattttgctcattggtatggtg
ggtaaaaacgctacgcttttaattgatgtggcgaatgaagagcgtaaaaaaggtttgaat
atccaagaagccattttatttgccggtaaaacccgtctaagaccgattttaatgacgacc
attgcgatggtttgtggcatgctgcctttagcgttggcgagtggggatggagcggcgatg
aaatcccctatagggattgcgatgagtgggggcttgatgatttctatggtgttaagctta
ctcattgtgccggtgttttatcgtttgctcgctcccatagacgacaaaatcaagcggttt
tatcaaaaccaaaaaactttagaatga

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