Haemophilus pittmaniae: NCTC13334_01781
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Entry
NCTC13334_01781 CDS
T06001
Symbol
metH
Name
(GenBank) homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
hpit
Haemophilus pittmaniae
Pathway
hpit00270
Cysteine and methionine metabolism
hpit00450
Selenocompound metabolism
hpit00670
One carbon pool by folate
hpit01100
Metabolic pathways
hpit01110
Biosynthesis of secondary metabolites
hpit01230
Biosynthesis of amino acids
hpit04981
Folate transport and metabolism
Module
hpit_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
hpit00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC13334_01781 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
NCTC13334_01781 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCTC13334_01781 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
NCTC13334_01781 (metH)
04980 Cobalamin transport and metabolism
NCTC13334_01781 (metH)
Enzymes [BR:
hpit01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
NCTC13334_01781 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
SNV86665
LinkDB
All DBs
Position
1:complement(1834914..1838600)
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AA seq
1228 aa
AA seq
DB search
MRNPAELLKKSLAERILILDGAMGTMIQKYKLTEADFRGERFKDSTVDLRGNNDLLTLTQ
PLLISAIHEKYLAAGADIIETNTFSSTTIAQADYDLQSIAYELNFAGAKLARLAADKYST
PEKPRFVAGVLGPTNRTASISPDVNDPGFRNITFMELVDAYAEATKGLIEGGADLIMIET
IFDTLNAKAAIFAIETVFEELGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAKPLT
FGLNCALGPKELRQYVEQLSKISETYVSVHPNAGLPNAFGGYDLGAEEMAAHLKEWAESG
FVNIVGGCCGTTPEHIKAFADAMQGIAPRKLPEIKTAMRLSGLEPLNIDDESLFVNVGER
NNVTGSAKFKRLIKEDKFAEAIEIAIDQVENGAQVIDVNMDEALLDGKKCMTRFLNIMAT
EPDAAKVPVMIDSSKWEVIEAGLQSVQGKPIVNSISLKEGEEIFIDHAKQVRKYGAAVVV
MAFDEVGQADTEDRKVEICSRAYDILVNQVGFPPEDIIFDPNIFAIGTGIEEHNNYGVDF
INATGRIKRALPHAKISGGVSNVSFSFRGNNVMREAIHAVFLYHAIKQGMDMGIVNAGQL
AIYDDLDPELREIVEDAVLNRSPDATEKLLDIAEKYRNQGTTQEDNTIAEWRTWPVEERL
KHALVKGITTHIVEDTEEARQQLPSPLDVIEGPLMAGMDVVGDLFGDGKMFLPQVVKSAR
VMKQSVAYLEPFINATKQKGSSNGKVVIATVKGDVHDIGKNIVSVVLQCNNFEVIDLGVM
VPADKIIQTAIDEKADIIGLSGLITPSLDEMEYFLGEMTRLGLNLPVLIGGATTSKEHTA
IKLYPKYKEHGVFYTSNASRAVTVCATLMNPESRVELWERFKQDYEKIQQSFANRKPLRK
QLSIEEARANRFDGFSGEWADYVPPKPNQTGIVEFKNVPIATLRKFIDWSPFFRIWGLMG
GYPDAFDYPEGGEEARKVWNDAQVVLDELEQNHKLNPSGILGIFPAERVGDDVVLFADEE
RSQPIGTAYGLRQQTERGKNSKSPFNFALSDFIADRKSGKKDWMGMFAVCAGIEEMDLVE
GYKAAGDDYNAILLQAVGDRLAEAMAEYLHFELRTRIWGYTQEEFDNQGLINENYVGIRP
APGYPSCPEHTEKALIWDLLEVEQRIGMKLTESYAMWPAASVCGWYFTHPASNYFTLGRI
DEDQAQDYAKRKGWDEREMMKWLGVAMK
NT seq
3687 nt
NT seq
+upstream
nt +downstream
nt
atgagaaatcccgccgaattactgaaaaaatccctcgctgaacgcatccttattttagat
ggtgcgatgggaacgatgatccaaaaatacaaactcaccgaggctgattttagaggcgaa
cgtttcaaagacagtacggtggatttgcgtgggaataatgatttgcttaccttaacccag
ccgttgttgatttctgcgattcatgagaaatatttggcagcgggcgcggatattattgaa
actaacactttcagttccaccaccattgcacaagcagattatgatttacaatccattgcc
tatgaactgaattttgcaggggcaaaattagcgcgtctggctgccgacaaatacagcaca
ccggaaaaacctcgctttgtcgcaggcgtgttagggccaaccaaccgtacagcctctatt
tcccctgatgtaaacgatccgggttttcgtaacattacctttatggaattagtggatgcc
tatgctgaagcgaccaaaggtttaatcgaaggtggtgcggatttgattatgatcgaaacc
attttcgacacgttaaacgcaaaagccgctattttcgcgattgaaaccgtgtttgaagaa
ttaggtgtggaattgccgattatgatttccggcaccattaccgatgcttccggccgtacg
ctttctgggcaaaccaccgaagcattctacaactcgcttcgtcacgctaaaccgctaact
ttcggtttgaactgtgcgctaggtccgaaagaactccgccaatatgttgaacaactgtct
aaaatcagcgaaacctatgtttctgtgcacccgaatgccggcttgccaaatgcctttggt
ggctacgatttaggggctgaagaaatggcggcacaccttaaagaatgggctgaaagtggc
tttgtgaacattgtcggcggttgttgtggtacaacgcctgaacatatcaaagcctttgcg
gatgcaatgcaaggtattgcaccgcgtaaattgccagaaattaaaaccgcgatgcgttta
tcgggcttagagcctcttaatattgatgatgaaagcctatttgtgaacgtgggtgaacgc
aataacgtgacaggttcggcgaaattcaaacgcttaattaaagaagacaaatttgccgaa
gccattgaaattgccatcgaccaagtggaaaacggcgcgcaagtgatcgatgtcaatatg
gacgaagccttgctagacggcaaaaaatgcatgactcgtttcctcaatattatggcaacc
gagccggatgctgccaaagtgccggtgatgatcgactcgtctaaatgggaagtgattgag
gcaggtttgcagtcggtgcaaggtaaaccgattgtgaactcaatctcattaaaagaaggc
gaagaaatctttatcgaccacgctaaacaggtgcgtaaatatggtgcagctgtggtagtc
atggcgtttgacgaagtaggtcaagccgataccgaagatcgcaaagtggaaatttgtagc
cgcgcttatgacattttggtgaaccaagtcggattcccaccagaagacattattttcgac
ccgaatatttttgccatcggtacggggattgaagaacacaacaactacggcgtggatttc
atcaacgctacaggccgtattaaacgagcgctaccgcatgcgaaaatctcaggcggggtg
tcgaatgtctctttctcattccgtggtaacaacgtgatgcgtgaagccattcacgccgtc
ttcctctatcacgccatcaaacaaggcatggatatggggattgtgaatgcggggcagctc
gcaatttatgacgatctcgatcctgaattgcgtgaaattgtagaagatgcggtgttaaat
cgcagcccggatgccaccgaaaaactactcgatattgcggaaaaatatcgtaatcaaggc
actacgcaagaagataataccatcgcagaatggcgcacttggccggtggaggaacgttta
aaacacgcccttgtgaaagggattacgacgcacatcgtagaagatacggaagaagcccgt
cagcaattgccaagcccattagatgtgattgaagggccacttatggcgggaatggatgtg
gtcggcgatttattcggtgacggtaaaatgttcctgccacaagtggtgaaatctgcgcgc
gtgatgaaacaatccgtggcgtacttagagccgtttattaacgcaaccaaacaaaaaggt
tcaagcaacggtaaagtggtgattgcgaccgtgaaaggcgatgtgcacgacatcggtaaa
aacattgtgagcgtggtcttgcaatgtaataactttgaagtgattgatttaggcgtgatg
gtgccggcggacaaaatcattcaaaccgccattgatgaaaaagccgatattattggcttg
agtggcttaattacgccatccctcgatgaaatggaatatttccttggtgaaatgactcgc
cttggtttgaacttgccggtgttgattggcggagctactacttccaaagaacatacagca
attaagctttatccaaaatacaaagaacacggcgtattttacacttccaacgcctcccgt
gcggtgacggtctgtgcaaccttaatgaatccggaaagtcgcgtagaattgtgggaacgt
tttaaacaggattacgagaaaatccaacaatcctttgccaatcgcaaaccgctacgcaaa
caactgagcattgaagaagcacgtgcgaaccgctttgatggctttagtggtgaatgggca
gattacgtgccaccgaaaccaaaccaaaccggtattgtggaatttaaaaatgtaccgatt
gccactctgcgtaaatttatcgactggtcaccattcttccgcatttggggcttgatgggc
ggctatccggatgcctttgattatccagaaggtggcgaagaagcacgcaaagtgtggaac
gatgcgcaagtggtcttagatgaattagagcaaaaccacaaactcaacccaagcggtatt
ttaggcatcttccctgcggaacgtgtgggcgatgatgtggtgctttttgctgatgaagaa
cgctctcaaccaatcggcaccgcttacggtttacgtcaacaaacggaacgcggcaaaaac
agcaaaagtccgtttaactttgccttaagcgactttattgccgatcgcaaaagcggtaaa
aaagactggatggggatgtttgccgtctgtgcgggtattgaagaaatggatctagtggaa
ggctataaagcagcgggtgatgactataacgctatcttgctacaagctgtgggcgatcgc
ttagcggaagccatggcggaatacttgcactttgagcttcgtacccgcatttggggctac
acgcaagaagaattcgacaatcaaggtttaatcaatgaaaactatgtcggcatccgcccg
gcaccgggttatccaagctgcccggaacacacggaaaaagccttgatttgggatttattg
gaagtcgaacaacgcatcggcatgaaactcaccgaaagctacgccatgtggccggcagct
tccgtctgcggttggtacttcacccaccctgcaagtaactatttcactttaggtcgcatt
gacgaagaccaagctcaagattatgccaaacgtaaaggctgggatgagagagagatgatg
aaatggttgggtgtggcgatgaagtga
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