Hydrogenophaga pseudoflava: HPF_01075
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Entry
HPF_01075 CDS
T06073
Symbol
metH2
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
hpse
Hydrogenophaga pseudoflava
Pathway
hpse00270
Cysteine and methionine metabolism
hpse00450
Selenocompound metabolism
hpse00670
One carbon pool by folate
hpse01100
Metabolic pathways
hpse01110
Biosynthesis of secondary metabolites
hpse01230
Biosynthesis of amino acids
hpse04980
Cobalamin transport and metabolism
hpse04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hpse00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HPF_01075 (metH2)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
HPF_01075 (metH2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
HPF_01075 (metH2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
HPF_01075 (metH2)
04980 Cobalamin transport and metabolism
HPF_01075 (metH2)
Enzymes [BR:
hpse01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
HPF_01075 (metH2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
Pterin_bind
B12-binding_2
B12-binding
Aldedh
Motif
Other DBs
NCBI-ProteinID:
QBM26250
UniProt:
A0A4P6WSC4
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Position
222326..225019
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AA seq
897 aa
AA seq
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MLLSGLEPLRIGEGSLFVNVGERTNVTGSKAFARMILEGRYEDALAVARQQVENGAQIVD
VNMDEAMLDSQAAMVRFLNLIAGEPDIARVPIMIDSSKWSVIEAGLQCIQGKGVVNSISM
KEGVEEFKRQAGLVKRYGAAAVVMAFDEKGQADTYERKIEICERAYRVLVDEVGFPPEDI
IFDPNIFAIATGIEEHNNYAVDFIEATRWIKANLPGAKVSGGVSNVSFSFRGNDPVREAI
HTVFLYHAIQAGMDMGIVNAGMVGVYDEIEPTLRERVEDVVLNRRPDAGERLVEVAESAK
GAAKDDSKKNEWRGLPIRERLTHALVRGINEHITEDTEEMWQLIKADGGRPLHVIEGPLM
DGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPYIEEEKRQLEAAGGDVKSKGKIVI
ATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILAKAKEEGADIVGLSGLITPSL
EEMQYVAGEMQKDAHFREQGIPLLIGGATTSRVHTAVKIAPHYDGPVVYVPDASRSVSVA
QSLIGDGRQQTIAELNADYERVRQQHANKKQVPLWPLAQARANATPVDFVAHPPVAPKFI
GRRVFRNFDLAELERYIDWGPFFQTWDLAGPYPAILQDEVVGEQARKVFADAQAMLKKII
EGRWLTANAVIGLYPANRVNADDIALYADETRQQPVLTWHGLRQQTEKEAVDGVTRPSRC
LADFVAPKGTPDYVGLFAVTAGVGVEKKEQQFLAAHDDYNAILFKSLADRLAEALAECMH
ARVRTDLWGYAAGETLSNDELIKEKYQGIRPAPGYPACPDHSVKRQMFELLQADEIGMAL
TESLAMSPAASVSGFYLAHPESTYFNVGRIGEDQVADLAARSGVAVSELKRWLGTNL
NT seq
2694 nt
NT seq
+upstream
nt +downstream
nt
atgctgctctccggcctggagccgctgcgcatcggcgagggcagcctgttcgtcaacgtc
ggcgagcgcaccaacgtcaccggctccaaggccttcgcccgcatgatcctcgaaggtcgc
tacgaggacgcgctggccgtggcccgccagcaggtggagaacggcgcgcagatcgtggac
gtgaacatggacgaggccatgctggacagccaggccgccatggtgcgtttcctgaacctg
atcgccggcgagcccgacatcgcgcgcgtgccgatcatgatcgactcgtccaagtggagc
gtgatcgaggccggcctgcagtgcatccagggcaagggcgtcgtcaactcgatttccatg
aaggagggcgtcgaggagttcaagcgccaggccgggctggtcaagcgctacggcgccgcc
gcggtggtgatggccttcgacgaaaagggccaggccgacacctacgaacgcaagatcgag
atctgcgaacgcgcctaccgcgtgctggtggacgaggtcggtttcccgcccgaggacatc
atcttcgaccccaacatcttcgccatcgccaccggcatcgaagaacacaacaactacgcg
gtcgacttcatcgaggccacgcgctggatcaaggcgaacctgccgggtgccaaggtcagc
ggcggcgtgtccaacgtgtcgttcagcttccgcggcaacgacccggtgcgcgaagccatc
cacaccgtgttcctgtaccacgcgatccaggcgggcatggacatgggcatcgtcaacgcc
ggtatggtgggcgtgtacgacgagatcgaacccacgctgcgcgagcgggtggaagacgtg
gtgctgaaccgccggcccgacgccggcgaacgcctggtggaagtggccgagagcgccaag
ggcgcggccaaggacgactcgaagaagaacgagtggcgcggcctgccgatccgcgaacgc
ctgacgcacgcgctggtgcgcggcatcaacgagcacatcaccgaagacaccgaggagatg
tggcagctcatcaaggccgacggcggccgcccgctgcacgtgatcgaaggtccgctgatg
gacggcatgaacgtggtcggcgacctgttcggcgccggcaagatgtttctgccccaggtg
gtgaaaagcgcgcgcgtgatgaagcaggcggtggcccacctgctgccctacatcgaggaa
gaaaaacgccagctcgaagcggccggcggcgacgtgaagagcaagggcaagatcgtgatc
gccaccgtcaagggcgacgtgcacgacatcggcaagaacatcgtcaccgtcgtgctccag
tgcaacaacttcgaggtggtgaacatgggcgtgatggtcccgtgccacgagatcctggcc
aaggccaaggaagagggggcggacatcgtgggcctgtcgggcctgatcacgcccagcctg
gaagagatgcagtacgtggccggcgagatgcagaaggacgcgcacttccgcgagcaaggc
attccgctgctgatcggcggcgccaccaccagccgcgtgcacacggccgtgaagatcgcg
ccgcactacgacggcccggtggtctacgtgcccgacgcctcgcgcagcgtgagcgtggcg
cagagcctcattggcgacggccgccagcagaccattgccgagctcaacgccgactacgag
cgcgtgcgccagcagcacgccaacaagaagcaggtgccgctgtggccgctggcgcaggcg
cgcgccaacgccacgccggtggacttcgtggcccacccgccggtggcgcccaagttcatc
ggtcgccgcgtgttcaggaacttcgacctggccgagctggagcgctacatcgactggggc
ccgttcttccagacctgggacctggccggcccgtacccggccatcctgcaggacgaggtg
gtgggcgagcaggcgcgcaaggtgttcgccgacgcgcaggccatgctcaagaagatcatc
gaaggccgctggctgacggccaacgcggtgatcggcctctacccggccaaccgggtgaat
gccgacgacatcgcgctctacgccgacgaaacccgccagcagccggtgctgacctggcac
ggcctgcgccagcagacggagaaggaagccgtcgatggcgtgacgcgcccgagccggtgt
ctcgccgacttcgtggcgcccaagggcacgcccgactacgtgggcctgttcgcggtgacg
gccggcgtgggcgtggagaagaaggagcagcagttcctggccgcgcacgacgactacaac
gccatcctgttcaagtccctggccgaccgcctggccgaggcgctggccgagtgcatgcac
gcccgcgtgcgcaccgacctctggggctacgccgcgggcgaaacgctctccaacgacgag
ctcatcaaggaaaagtaccagggcatccgcccggcgccgggttacccggcctgcccggac
cacagcgtcaagcgccagatgttcgagctgctgcaggccgatgagatcggcatggcgctc
accgaaagcctggccatgagcccggccgccagcgtcagcggtttctacctggcgcacccc
gagagcacctatttcaacgtcggccgcatcggcgaggaccaggtggccgacctggccgcg
cgcagcggcgtggcggtcagcgagctcaagcgctggctcggcaccaacctctga
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