KEGG   Hydrogenophaga pseudoflava: HPF_01075
Entry
HPF_01075         CDS       T06073                                 
Symbol
metH2
Name
(GenBank) Methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
hpse  Hydrogenophaga pseudoflava
Pathway
hpse00270  Cysteine and methionine metabolism
hpse00450  Selenocompound metabolism
hpse00670  One carbon pool by folate
hpse01100  Metabolic pathways
hpse01110  Biosynthesis of secondary metabolites
hpse01230  Biosynthesis of amino acids
hpse04980  Cobalamin transport and metabolism
hpse04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:hpse00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    HPF_01075 (metH2)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    HPF_01075 (metH2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HPF_01075 (metH2)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    HPF_01075 (metH2)
   04980 Cobalamin transport and metabolism
    HPF_01075 (metH2)
Enzymes [BR:hpse01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     HPF_01075 (metH2)
SSDB
Motif
Pfam: Met_synt_B12 Pterin_bind B12-binding_2 B12-binding Aldedh
Other DBs
NCBI-ProteinID: QBM26250
UniProt: A0A4P6WSC4
LinkDB
Position
222326..225019
AA seq 897 aa
MLLSGLEPLRIGEGSLFVNVGERTNVTGSKAFARMILEGRYEDALAVARQQVENGAQIVD
VNMDEAMLDSQAAMVRFLNLIAGEPDIARVPIMIDSSKWSVIEAGLQCIQGKGVVNSISM
KEGVEEFKRQAGLVKRYGAAAVVMAFDEKGQADTYERKIEICERAYRVLVDEVGFPPEDI
IFDPNIFAIATGIEEHNNYAVDFIEATRWIKANLPGAKVSGGVSNVSFSFRGNDPVREAI
HTVFLYHAIQAGMDMGIVNAGMVGVYDEIEPTLRERVEDVVLNRRPDAGERLVEVAESAK
GAAKDDSKKNEWRGLPIRERLTHALVRGINEHITEDTEEMWQLIKADGGRPLHVIEGPLM
DGMNVVGDLFGAGKMFLPQVVKSARVMKQAVAHLLPYIEEEKRQLEAAGGDVKSKGKIVI
ATVKGDVHDIGKNIVTVVLQCNNFEVVNMGVMVPCHEILAKAKEEGADIVGLSGLITPSL
EEMQYVAGEMQKDAHFREQGIPLLIGGATTSRVHTAVKIAPHYDGPVVYVPDASRSVSVA
QSLIGDGRQQTIAELNADYERVRQQHANKKQVPLWPLAQARANATPVDFVAHPPVAPKFI
GRRVFRNFDLAELERYIDWGPFFQTWDLAGPYPAILQDEVVGEQARKVFADAQAMLKKII
EGRWLTANAVIGLYPANRVNADDIALYADETRQQPVLTWHGLRQQTEKEAVDGVTRPSRC
LADFVAPKGTPDYVGLFAVTAGVGVEKKEQQFLAAHDDYNAILFKSLADRLAEALAECMH
ARVRTDLWGYAAGETLSNDELIKEKYQGIRPAPGYPACPDHSVKRQMFELLQADEIGMAL
TESLAMSPAASVSGFYLAHPESTYFNVGRIGEDQVADLAARSGVAVSELKRWLGTNL
NT seq 2694 nt   +upstreamnt  +downstreamnt
atgctgctctccggcctggagccgctgcgcatcggcgagggcagcctgttcgtcaacgtc
ggcgagcgcaccaacgtcaccggctccaaggccttcgcccgcatgatcctcgaaggtcgc
tacgaggacgcgctggccgtggcccgccagcaggtggagaacggcgcgcagatcgtggac
gtgaacatggacgaggccatgctggacagccaggccgccatggtgcgtttcctgaacctg
atcgccggcgagcccgacatcgcgcgcgtgccgatcatgatcgactcgtccaagtggagc
gtgatcgaggccggcctgcagtgcatccagggcaagggcgtcgtcaactcgatttccatg
aaggagggcgtcgaggagttcaagcgccaggccgggctggtcaagcgctacggcgccgcc
gcggtggtgatggccttcgacgaaaagggccaggccgacacctacgaacgcaagatcgag
atctgcgaacgcgcctaccgcgtgctggtggacgaggtcggtttcccgcccgaggacatc
atcttcgaccccaacatcttcgccatcgccaccggcatcgaagaacacaacaactacgcg
gtcgacttcatcgaggccacgcgctggatcaaggcgaacctgccgggtgccaaggtcagc
ggcggcgtgtccaacgtgtcgttcagcttccgcggcaacgacccggtgcgcgaagccatc
cacaccgtgttcctgtaccacgcgatccaggcgggcatggacatgggcatcgtcaacgcc
ggtatggtgggcgtgtacgacgagatcgaacccacgctgcgcgagcgggtggaagacgtg
gtgctgaaccgccggcccgacgccggcgaacgcctggtggaagtggccgagagcgccaag
ggcgcggccaaggacgactcgaagaagaacgagtggcgcggcctgccgatccgcgaacgc
ctgacgcacgcgctggtgcgcggcatcaacgagcacatcaccgaagacaccgaggagatg
tggcagctcatcaaggccgacggcggccgcccgctgcacgtgatcgaaggtccgctgatg
gacggcatgaacgtggtcggcgacctgttcggcgccggcaagatgtttctgccccaggtg
gtgaaaagcgcgcgcgtgatgaagcaggcggtggcccacctgctgccctacatcgaggaa
gaaaaacgccagctcgaagcggccggcggcgacgtgaagagcaagggcaagatcgtgatc
gccaccgtcaagggcgacgtgcacgacatcggcaagaacatcgtcaccgtcgtgctccag
tgcaacaacttcgaggtggtgaacatgggcgtgatggtcccgtgccacgagatcctggcc
aaggccaaggaagagggggcggacatcgtgggcctgtcgggcctgatcacgcccagcctg
gaagagatgcagtacgtggccggcgagatgcagaaggacgcgcacttccgcgagcaaggc
attccgctgctgatcggcggcgccaccaccagccgcgtgcacacggccgtgaagatcgcg
ccgcactacgacggcccggtggtctacgtgcccgacgcctcgcgcagcgtgagcgtggcg
cagagcctcattggcgacggccgccagcagaccattgccgagctcaacgccgactacgag
cgcgtgcgccagcagcacgccaacaagaagcaggtgccgctgtggccgctggcgcaggcg
cgcgccaacgccacgccggtggacttcgtggcccacccgccggtggcgcccaagttcatc
ggtcgccgcgtgttcaggaacttcgacctggccgagctggagcgctacatcgactggggc
ccgttcttccagacctgggacctggccggcccgtacccggccatcctgcaggacgaggtg
gtgggcgagcaggcgcgcaaggtgttcgccgacgcgcaggccatgctcaagaagatcatc
gaaggccgctggctgacggccaacgcggtgatcggcctctacccggccaaccgggtgaat
gccgacgacatcgcgctctacgccgacgaaacccgccagcagccggtgctgacctggcac
ggcctgcgccagcagacggagaaggaagccgtcgatggcgtgacgcgcccgagccggtgt
ctcgccgacttcgtggcgcccaagggcacgcccgactacgtgggcctgttcgcggtgacg
gccggcgtgggcgtggagaagaaggagcagcagttcctggccgcgcacgacgactacaac
gccatcctgttcaagtccctggccgaccgcctggccgaggcgctggccgagtgcatgcac
gcccgcgtgcgcaccgacctctggggctacgccgcgggcgaaacgctctccaacgacgag
ctcatcaaggaaaagtaccagggcatccgcccggcgccgggttacccggcctgcccggac
cacagcgtcaagcgccagatgttcgagctgctgcaggccgatgagatcggcatggcgctc
accgaaagcctggccatgagcccggccgccagcgtcagcggtttctacctggcgcacccc
gagagcacctatttcaacgtcggccgcatcggcgaggaccaggtggccgacctggccgcg
cgcagcggcgtggcggtcagcgagctcaagcgctggctcggcaccaacctctga

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