Homo sapiens (human): 100137049 Help Entry 100137049         CDS       T01001                                  Symbol PLA2G4B, HsT16992, cPLA2-beta Name (RefSeq) phospholipase A2 group IVB   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     100137049 (PLA2G4B)    00565 Ether lipid metabolism     100137049 (PLA2G4B)    00590 Arachidonic acid metabolism     100137049 (PLA2G4B)    00591 Linoleic acid metabolism     100137049 (PLA2G4B)    00592 alpha-Linolenic acid metabolism     100137049 (PLA2G4B)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100137049 (PLA2G4B)    04014 Ras signaling pathway     100137049 (PLA2G4B)    04370 VEGF signaling pathway     100137049 (PLA2G4B)    04072 Phospholipase D signaling pathway     100137049 (PLA2G4B)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     100137049 (PLA2G4B)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100137049 (PLA2G4B)    04664 Fc epsilon RI signaling pathway     100137049 (PLA2G4B)    04666 Fc gamma R-mediated phagocytosis     100137049 (PLA2G4B)   09152 Endocrine system    04912 GnRH signaling pathway     100137049 (PLA2G4B)    04913 Ovarian steroidogenesis     100137049 (PLA2G4B)    04921 Oxytocin signaling pathway     100137049 (PLA2G4B)   09153 Circulatory system    04270 Vascular smooth muscle contraction     100137049 (PLA2G4B)   09156 Nervous system    04724 Glutamatergic synapse     100137049 (PLA2G4B)    04726 Serotonergic synapse     100137049 (PLA2G4B)    04730 Long-term depression     100137049 (PLA2G4B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100137049 (PLA2G4B)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100137049 (PLA2G4B) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      100137049 (PLA2G4B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  100137049 NCBI-ProteinID:  NP_001108105 OMIM:  606088 HGNC:  9036 Ensembl:  ENSG00000243708 UniProt:  P0C869 LinkDB All DBs Position 15:41838847..41848143 Genome browser AA seq 781 aa AA seqDB search MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP H NT seq 2346 nt NT seq  +upstreamnt  +downstreamnt atggctgtggcagaggtgtccaggacctgcctgctcacggttcgtgtcctgcaggcccat cgcctaccctctaaggacctagtgaccccctctgactgctacgtgactctctggctgccc acggcctgcagccacaggctccagacacgcacggtcaagaacagcagtagccctgtctgg aaccagagctttcacttcaggatccacaggcagctcaagaatgtcatggaactgaaagtc tttgaccaggacctggtgaccggagatgaccctgtgttgtcagtactgtttgatgcgggg actctgcgggctggggagttccggcgcgagagcttctcactgagccctcagggtgagggg cgcctggaagttgaatttcgcctgcagagtctggctgaccgtggcgagtggctcgtcagc aatggcgttctggtggcccgggagctctcctgcttgcacgttcaactggaggagacagga gaccagaagtcctcagagcacagagttcagcttgtggttcctgggtcctgtgagggtccg caggaggcctctgtgggcactggcaccttccgcttccactgcccagcctgctgggagcag gagctgagtattcgcctgcaggatgcccccgaggagcaactaaaggcgccactgagtgcc ctgccctctggtcaagtggtgaggcttgtcttccccacgtcccaggagcccctgatgaga gtggagctgaaaaaagaagcaggactgagggagctggccgtgcgactgggcttcgggccc tgtgcagaggagcaggccttcctgagcaggaggaagcaggtggtggccgcggccttgagg caggccctgcagctggacggagacctgcaggaggatgagatcccagtggtagctattatg gccactggtggtgggatccgggcaatgacttccctgtatgggcagctggctggcctgaag gagctgggcctcttggattgcgtctcctacatcaccggggcctcgggctccacctgggcc ttggccaacctttatgaggacccagagtggtctcagaaggacctggcagggcccactgag ttgctgaagacccaggtgaccaagaacaagctgggtgtgctggcccccagccagctgcag cggtaccggcaggagctggccgagcgtgcccgcttgggctacccaagctgcttcaccaac ctgtgggccctcatcaacgaggcgctgctgcatgatgagccccatgatcacaagctctca gatcaacgggaggccctgagtcatggccagaaccctctgcccatctactgtgccctcaac accaaagggcagagcctgaccacttttgaatttggggagtggtgcgagttctctccctac gaggtcggcttccccaagtacggggccttcatcccctctgagctctttggctccgagttc tttatggggcagctgatgaagaggcttcctgagtcccgcatctgcttcttagaaggtatc tggagcaacctgtatgcagccaacctccaggacagcttatactgggcctcagagcccagc cagttctgggaccgctgggtcaggaaccaggccaacctggacaaggagcaggtccccctt ctgaagatagaagaaccaccctcaacagccggcaggatagctgagtttttcaccgatctt ctgacgtggcgtccactggcccaggccacacataatttcctgcgtggcctccatttccac aaagactactttcagcatcctcacttctccacatggaaagctaccactctggatgggctc cccaaccagctgacaccctcggagccccacctgtgcctgctggatgttggctacctcatc aataccagctgcctgcccctcctgcagcccactcgggacgtggacctcatcctgtcattg gactacaacctccacggagccttccagcagttgcagctcctgggccggttctgccaggag caggggatcccgttcccacccatctcgcccagccccgaagagcagctccagcctcgggag tgccacaccttctccgaccccacctgccccggagcccctgcggtgctgcactttcctctg gtcagcgactccttccgggagtactcggcccctggggtccggcggacacccgaggaggcg gcagctggggaggtgaacctgtcttcatcggactctccctaccactacacgaaggtgacc tacagccaggaggacgtggacaagctgctgcacctgacacattacaatgtctgcaacaac caggagcagctgctggaggctctgcgccaggcagtgcagcggaggcggcagcgcaggccc cactga

Homo sapiens (human): 123745 Help Entry 123745            CDS       T01001                                  Symbol PLA2G4E Name (RefSeq) phospholipase A2 group IVE   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     123745 (PLA2G4E)    00565 Ether lipid metabolism     123745 (PLA2G4E)    00590 Arachidonic acid metabolism     123745 (PLA2G4E)    00591 Linoleic acid metabolism     123745 (PLA2G4E)    00592 alpha-Linolenic acid metabolism     123745 (PLA2G4E)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     123745 (PLA2G4E)    04014 Ras signaling pathway     123745 (PLA2G4E)    04370 VEGF signaling pathway     123745 (PLA2G4E)    04072 Phospholipase D signaling pathway     123745 (PLA2G4E)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     123745 (PLA2G4E)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     123745 (PLA2G4E)    04664 Fc epsilon RI signaling pathway     123745 (PLA2G4E)    04666 Fc gamma R-mediated phagocytosis     123745 (PLA2G4E)   09152 Endocrine system    04912 GnRH signaling pathway     123745 (PLA2G4E)    04913 Ovarian steroidogenesis     123745 (PLA2G4E)    04921 Oxytocin signaling pathway     123745 (PLA2G4E)   09153 Circulatory system    04270 Vascular smooth muscle contraction     123745 (PLA2G4E)   09156 Nervous system    04724 Glutamatergic synapse     123745 (PLA2G4E)    04726 Serotonergic synapse     123745 (PLA2G4E)    04730 Long-term depression     123745 (PLA2G4E)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     123745 (PLA2G4E)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     123745 (PLA2G4E) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      123745 (PLA2G4E) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  123745 NCBI-ProteinID:  NP_001193599 OMIM:  620649 HGNC:  24791 Ensembl:  ENSG00000188089 UniProt:  Q3MJ16 LinkDB All DBs Position 15:complement(41981582..42050703) Genome browser AA seq 868 aa AA seqDB search MSLQASEGCPGLGTNVFVPQSPQTDEEGSRSGRSFSEFEDTQDLDTPGLPPFCPMAPWGS EEGLSPCHLLTVRVIRMKNVRQADMLSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNE SFNFQIQSRVKNVLELSVCDEDTVTPDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEEL EVEFLLEESPSPPETLVTNGVLVSRQVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQ RVRPCLEPCCPTSACFQTAACFHYPKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLD CLSDGQVMTLPVGESYELHMKSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVL QLEEDLQEDEVPLIAIMATGGGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMAT LYRDPDWSSKNLEPAIFEARRHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWG LLIETCLGDERNECKLSDQRAALSCGQNPLPIYLTINVKDDVSNQDFREWFEFSPYEVGL QKYGAFIPSELFGSEFFMGRLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFH RWTREKVQDIEDEPILPEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLS GLQLHTNYLQNGQFSRWKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKAD LIIHLNYCAGSQTKPLKQTCEYCTVQNIPFPKYELPDENENLKECYLMENPQEPDAPIVT FFPLINDTFRKYKAPGVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYN ILNNKDTLLQALRLAVEKKKRLKGQCPS NT seq 2607 nt NT seq  +upstreamnt  +downstreamnt atgagtctccaggcctcggaaggctgtcctggcctgggaactaatgtgtttgtcccacag agcccacaaacggatgaagaaggcagcaggtcaggaagaagtttcagtgagttcgaggat acacaggacctggacactcctggtctcccacctttctgtcctatggctccttggggctct gaggaggggctgtctccatgccacctgttgacagtgagggtcatccggatgaaaaatgtc cggcaggctgatatgctgagccagacagactgttttgtgagcctctggctgcccaccgcc tctcagaagaagctgaggacaaggaccatctccaactgcccaaatccagagtggaatgaa agcttcaacttccagatccagagccgagtgaagaacgtgctagagttgagtgtctgtgat gaagacacagtgacaccagatgaccatctcctgacagttctctatgacctcaccaagctc tgtttccgaaagaaaacccacgtgaagtttccactcaacccgcagggcatggaagagctg gaggtggagttcctgctggaggagagtccctctccacctgagaccctcgtcaccaatggc gtgctggtgtctcgacaagtctcctgcctggaggttcatgcacaatccaggaggcggagg aagagggagaaaatgaaggacctcctggtgatggtgaacgaatcctttgagaacacccag cgtgtccggccctgcttggaaccctgctgcccaacctctgcctgcttccaaaccgctgcc tgcttccactaccccaagtacttccagtcccaggtgcacgtggaagtgcccaagagtcac tggagctgtgggctttgctgccgctctcgcaagaagggccccatcagccagcccctcgac tgcctttccgatggtcaggtgatgaccctgcctgtgggtgagagttatgaattacacatg aagtctacaccctgccctgagacactggacgtgcggctgggcttcagcctgtgcccagca gagctggagtttctgcagaagcggaaggtcgtggtggccaaggccctgaagcaggtgctg cagctggaggaagacctgcaggaggacgaggtgccgctgatagccatcatggccactggg ggtggaacaagatccatgacctccatgtatggccacctgctggggctgcagaagctgaac ctcctggactgtgccagctacatcaccggtctatcaggggccacctggaccatggctacc ttgtaccgtgaccctgactggtcctccaaaaacttggagcctgctatctttgaggctcgg agacatgtggtaaaggacaagctaccctccctgttcccagaccagctccgcaaattccag gaggagctccggcagcgcagccaggaaggctacagggtcacctttacagacttctggggc ctgctgatagagacctgcctgggggacgagagaaatgaatgcaaactgtcagatcagcgt gctgctttgagctgcggccagaaccccctgcccatctacctcaccatcaatgtcaaggat gatgtaagcaaccaggacttcagagagtggttcgagttctccccctacgaggtgggcctg cagaagtatggggccttcatcccctccgagctcttcggctccgagttcttcatggggcgg ctggtgaagaggatcccggagtctcgaatctgctacatgctaggcctgtggagcagcatc ttctccctgaacctgctggatgcctggaacctgtcacacacctcggaggagtttttccac aggtggacaagggagaaagtgcaggacatcgaagacgagccgatcctgcctgaaatcccc aaatgtgatgctaacatcctggagaccacggtagtgatcccagggtcatggctgtccaat tctttccgagaaatccttacccatcggtccttcgtgtctgagtttcacaacttcctgtct gggctgcagctgcacaccaactacctccagaatggccagttctctaggtggaaagacaca gtgctagatggtttcccaaaccagctgaccgagtccgcgaaccacctgtgcctgctggac actgcgttctttgtcaactccagctacccgcccctcctcaggccagagcgaaaagccgac ctcatcatccacctcaactactgtgctgggtcccagacaaagcccctgaaacaaacctgt gagtactgcactgtgcagaacatccccttccccaaatacgagctgccagatgagaatgaa aatctcaaggaatgctacctgatggagaacccccaggaacccgatgcccccatcgtgact ttcttcccactcatcaatgacactttccgaaaatacaaggcaccaggtgtagagcgaagc cctgaggagctggagcagggccaggtggacatttatggtcccaaaactccctatgccacc aaggagctgacatacacagaggccacctttgacaagctggtgaaactctcagagtataac atcctgaataataaggacactctcctccaggctctgcggctcgcagtggagaagaagaag cgcctgaagggccagtgtccctcctag

Homo sapiens (human): 255189 Help Entry 255189            CDS       T01001                                  Symbol PLA2G4F, PLA2G4FZ Name (RefSeq) phospholipase A2 group IVF   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     255189 (PLA2G4F)    00565 Ether lipid metabolism     255189 (PLA2G4F)    00590 Arachidonic acid metabolism     255189 (PLA2G4F)    00591 Linoleic acid metabolism     255189 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     255189 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     255189 (PLA2G4F)    04014 Ras signaling pathway     255189 (PLA2G4F)    04370 VEGF signaling pathway     255189 (PLA2G4F)    04072 Phospholipase D signaling pathway     255189 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     255189 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     255189 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     255189 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     255189 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     255189 (PLA2G4F)    04913 Ovarian steroidogenesis     255189 (PLA2G4F)    04921 Oxytocin signaling pathway     255189 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     255189 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     255189 (PLA2G4F)    04726 Serotonergic synapse     255189 (PLA2G4F)    04730 Long-term depression     255189 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     255189 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     255189 (PLA2G4F) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      255189 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  255189 NCBI-ProteinID:  NP_998765 HGNC:  27396 Ensembl:  ENSG00000168907 UniProt:  Q68DD2 A5PKZ7 LinkDB All DBs Position 15:complement(42139034..42156636) Genome browser AA seq 849 aa AA seqDB search MLWALWPRWLADKMLPLLGAVLLQKREKRGPLWRHWRRETYPYYDLQVKVLRATNIRGTD LLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGAVKNVLELTLYDKDIL GSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKSQVPASEVITNGVLVAH PCLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQPPTEPGLPPTFTFHVNPV LSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLPLGQEEQCSVALGEGQEVA LSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQVLGLSEALDSGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYRDPAWSQVALQGPIE RAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLWGLLVEYLLYQEENPAKLS DQQEAVRQGQNPYPIYTSVNVRTNLSGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSELF MGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLSFLEWYRGSVNITDDCQKPQ LHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRGLCLHKDYVAGREFVAWKDT HPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDLILSFDYSLEAPFEVLKMTE KYCLDRGIPFPSIEVGPEDMEEARECYLFAKAEDPRSPIVLHFPLVNRTFRTHLAPGVER QTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRYNVLNNVETLKCALQLALDR HQARERAGA NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgctttgggcactctggccaaggtggctggcagacaagatgctgcccctcctgggggca gtgctgcttcagaagagagagaagaggggccctctgtggaggcactggcggcgggaaacc tacccatactatgacctccaggtgaaggtgctgagggccacaaacatccggggcacagac ctgctgtccaaagccgactgctatgtgcaactgtggctgcccacggcgtccccaagccct gcccagactaggatagtggccaactgcagtgaccccgagtggaatgagaccttccactac cagatccatggtgctgtgaagaacgtcctggagctcaccctctatgacaaggacatcctg ggcagcgaccagctctctctgctcctgtttgacctgagaagcctcaagtgtggccaacct cacaaacacaccttcccactcaaccaccaggattcacaagagctgcaggtggaatttgtt ctggagaagagccaggtgcctgcatctgaagtcatcaccaacggggttctggtggctcac ccctgtctgagaatccagggcacgctccggggagatgggacagccccacgggaagagtac ggctctaggcagctccagctggcagtgcctggagcctacgagaagccacagctcttgccc ctgcagcctcccacagagccaggcctcccacccacctttaccttccacgtgaacccagtg ctgagctccaggctacacgtggagctgatggagctgctggcagctgtgcagagtggcccc agcgcagagttggaggctcagaccagcaagctgggcgaggggggcatcctgctctcctct ctgcccctaggccaggaggaacagtgttctgtggccctgggggagggccaggaggtggct ctgagcatgaaggtggaaatgagctccggggacctagacctacgccttggctttgacctc tctgacggggagcaggagtttctggacaggaggaagcaggtcgtgtccaaggccctgcag caagtgctgggattgagtgaggctctggacagtggccaggtgcctgtagtggctgtgttg ggttccgggggtggaacccgagccatgtcttctctgtacggcagcctggcagggttgcag gagctcggccttctagacactgtgacctacctgagtggggtctctgggtctacctggtgc atctccacactctacagggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggttcacgtctgcagcagtaagatgggagctttgtccacggagcggctacag tactacactcaggaactgggggtccgggagcgcagtggccacagcgtgtccctcatcgac ctctggggcctccttgttgagtatctcctgtaccaggaggagaaccctgccaagctgtct gaccaacaggaggcggtccgccagggtcagaacccttaccccatttacaccagtgtcaac gtccgcaccaacttgagtggggaagattttgcagagtggtgcgagttcacgccctatgag gttggcttccccaagtacggggcttatgttcccaccgagctcttcggctcagaactcttc atgggacgattgctgcagctccagcctgaaccccggatctgttacctgcaaggtatgtgg ggcagcgcctttgccaccagcctggatgagatcttcctaaagaccgccggctcgggcctc agcttcctggagtggtacagaggcagtgtgaatatcacagacgactgccagaagcctcag ctgcacaacccctcgaggctgcgaacgaggctcctcaccccacaggggcccttctcccag gctgtgctggacatattcacctcccgcttcacttccgcccagagctttaacttcacccgg ggtctctgcttgcacaaggactatgtggctggcagggagttcgtggcctggaaagacaca cacccggacgccttccccaaccagctcacccccatgcgggactgcctgtacctggtggac ggaggctttgccatcaactctccgttcccactggctctgctgcctcagagagcagtggac ctcattctgtcctttgactattccttggaagccccttttgaggtcttgaagatgacagag aagtactgcctggaccgaggaatccccttccctagcatcgaggtgggccctgaggacatg gaggaggcccgtgagtgctatctgtttgccaaggctgaggacccccgctcccccattgtg ctgcacttccccctggttaaccgtaccttccgcacacacctggccccaggtgtggagcga caaacagctgaggagaaggcctttggggactttgtcatcaacaggccagacaccccctat ggcatgatgaacttcacctatgagccccaggacttttatcggctggtggccctcagtcga tacaacgtcctgaacaacgtggagaccttgaagtgcgccctccagctggctctggaccgg caccaggctcgggagagggcaggggcctga

Homo sapiens (human): 283748 Help Entry 283748            CDS       T01001                                  Symbol PLA2G4D, cPLA2delta Name (RefSeq) phospholipase A2 group IVD   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     283748 (PLA2G4D)    00565 Ether lipid metabolism     283748 (PLA2G4D)    00590 Arachidonic acid metabolism     283748 (PLA2G4D)    00591 Linoleic acid metabolism     283748 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     283748 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     283748 (PLA2G4D)    04014 Ras signaling pathway     283748 (PLA2G4D)    04370 VEGF signaling pathway     283748 (PLA2G4D)    04072 Phospholipase D signaling pathway     283748 (PLA2G4D)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     283748 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     283748 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     283748 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     283748 (PLA2G4D)   09152 Endocrine system    04912 GnRH signaling pathway     283748 (PLA2G4D)    04913 Ovarian steroidogenesis     283748 (PLA2G4D)    04921 Oxytocin signaling pathway     283748 (PLA2G4D)   09153 Circulatory system    04270 Vascular smooth muscle contraction     283748 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     283748 (PLA2G4D)    04726 Serotonergic synapse     283748 (PLA2G4D)    04730 Long-term depression     283748 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     283748 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     283748 (PLA2G4D) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      283748 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  283748 NCBI-ProteinID:  NP_828848 OMIM:  612864 HGNC:  30038 Ensembl:  ENSG00000159337 UniProt:  Q86XP0 Structure PDB LinkDB All DBs Position 15:complement(42067009..42094562) Genome browser AA seq 818 aa AA seqDB search MESLSPGGPPGHPYQGEASTCWQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFK TKTLTDTSHPVWNEAFRFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLL RKTFSQSPQGEEELDVEFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQ DKLELELVLKGSYEDTQTSFLGTASAFRFHYMAALETELSGRLRSSRSNGWNGDNSAGYL TVPLRPLTIGKEVTMDVPAPNAPGVRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQV VAKALKQALQLDRDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGI SGSTWTMAHLYGDPEWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGH PTTFVDLWALVLESMLHGQVMDQKLSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEW VEFSPYEVGFLKYGAFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWY DLTSSGESWKQHIKDKTRSLEKEPLTTSGTSSRLEASWLQPGTALAQAFKGFLTGRPLHQ RSPNFLQGLQLHQDYCSHKDFSTWADYQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMF RPGRRLDLILSFDYSLSAPFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPA CPEAPILLHFPLVNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFER LLRLSDYNVQTSQGAILQALRTALKHRTLEARPPRAQT NT seq 2457 nt NT seq  +upstreamnt  +downstreamnt atggagagcctgtcacctgggggaccacctggccacccttaccagggggaggcctctacc tgctggcagctcacagtgagggtcctggaggcgcggaacctgcgctgggctgacctgttg agtgaggccgacccttacgtgatcctacagctgtcgaccgcacctggaatgaagtttaag accaagacgctcaccgacaccagtcatcctgtgtggaatgaggccttccgtttccttatc caaagtcaggtcaagaatgttctggagcttagcatctatgatgaggactcagtcacggag gatgacatctgcttcaaggttctctatgacatctcagaagtcctccctggcaagctgctc cggaaaaccttctcccagagtccccagggagaggaggagctggatgtggagttcctgatg gaagaaacgtcagatcgcccagaaaacctcatcaccaacaaagtcattgtggcccgagag ctgtcatgcctggatgtgcatctggacagcacagggagcaccgctgtggttgcagatcag gacaagctggagctggagctggtgctgaaggggtcctatgaggacacacagacatccttc ctgggcacagcctctgccttccgcttccactacatggcagccctagagacagagctgagc gggcgcctgaggagctccagaagcaatggctggaatggggacaactcagctgggtacctc actgtgcccctgaggcccttgaccattgggaaggaggtgactatggatgttcctgctcca aatgccccaggagtgaggctgcagctcaaggcagagggctgccctgaggagctggccgtg cacctgggcttcaatctctgtgcagaggagcaggccttcctgagcaggaggaagcaggtg gtggccaaggccctgaagcaggccctgcagctggacagagacctgcaggaggatgaggta cccgttgtgggcatcatggccacaggaggaggtgcccgggccatgacctcactctacggc cacctattggccttgcagaagctgggcctcctagactgtgtgacctacttcagtggcatc tctggctctacgtggacaatggcccacctgtacggggaccctgagtggtcgcagagggac ctggagggacctatcagatacgcccgggagcacctggccaagagcaagctggaggtcttt tccccagagcgcctggcgagctaccgccgggagctggagctgcgggctgagcagggccac cccacgacctttgtggacctgtgggcgctagtgctggagtccatgctgcacggccaggtg atggatcagaagctgtcaggacagagagccgccctggaacggggtcagaaccctctgccc ctctacttgagcctcaatgtcaaagagaacaatctggagacactggacttcaaggagtgg gttgagttctccccctatgaggtcggtttcctgaagtacggggccttcgtccctcctgag ctcttcggctccgagttcttcatgggacggctgatgaggaggatcccggagccccggatc tgctttctggaagccatctggagcaacattttctccctgaacctgctggatgcctggtat gacctcaccagttctggggagtcctggaaacagcacatcaaggacaagaccaggagctta gagaaggagcccctgaccacctcggggacctcctcgcggctggaggcctcgtggctgcag ccaggcacggcgctggcccaggcatttaaaggcttcctgacaggcaggcccctccaccag cgcagccccaacttcctccagggcctccagctgcaccaggactactgtagccacaaagac ttctccacctgggcagactaccagcttgactccatgcccagccagctgacccccaaggag ccccggctctgcctggtggacgccgcctacttcatcaacaccagctctccctccatgttc cggccaggccgcaggctggacctcatcctctccttcgactactccctatctgcgcccttc gaggcactgcagcagacggagctgtactgccgggcccgggggctgcccttcccccgggtg gaacccagccctcaggaccagcaccagccaagggaatgccacctcttctcagaccccgcc tgccccgaggccccgatcctgctgcacttcccgctggtcaatgcctccttcaaggaccac tcagcccccggtgtccagcgcagccccgcagagctccagggtggccaagtggatctcacc ggggccacctgcccctacaccctgtccaacatgacctacaaggaggaagacttcgagcgc ctgctgcggctcagtgactacaacgtgcagaccagccagggtgccatcctgcaggccctg aggaccgcgctgaagcaccggactctagaggcgaggcctccaagggcacagacctga

Homo sapiens (human): 5321 Help Entry 5321              CDS       T01001                                  Symbol PLA2G4A, GURDP, PLA2G4, cPLA2, cPLA2-alpha Name (RefSeq) phospholipase A2 group IVA   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Disease H02504   Gastrointestinal ulceration, recurrent, with dysfunctional platelets Drug target Ecopladib:  D03938 Efipladib:  D06674 Giripladib:  D06600 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     5321 (PLA2G4A)    00565 Ether lipid metabolism     5321 (PLA2G4A)    00590 Arachidonic acid metabolism     5321 (PLA2G4A)    00591 Linoleic acid metabolism     5321 (PLA2G4A)    00592 alpha-Linolenic acid metabolism     5321 (PLA2G4A)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     5321 (PLA2G4A)    04014 Ras signaling pathway     5321 (PLA2G4A)    04370 VEGF signaling pathway     5321 (PLA2G4A)    04072 Phospholipase D signaling pathway     5321 (PLA2G4A)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     5321 (PLA2G4A)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     5321 (PLA2G4A)    04664 Fc epsilon RI signaling pathway     5321 (PLA2G4A)    04666 Fc gamma R-mediated phagocytosis     5321 (PLA2G4A)   09152 Endocrine system    04912 GnRH signaling pathway     5321 (PLA2G4A)    04913 Ovarian steroidogenesis     5321 (PLA2G4A)    04921 Oxytocin signaling pathway     5321 (PLA2G4A)   09153 Circulatory system    04270 Vascular smooth muscle contraction     5321 (PLA2G4A)   09156 Nervous system    04724 Glutamatergic synapse     5321 (PLA2G4A)    04726 Serotonergic synapse     5321 (PLA2G4A)    04730 Long-term depression     5321 (PLA2G4A)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     5321 (PLA2G4A)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     5321 (PLA2G4A) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      5321 (PLA2G4A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B C2 cPLA2_C2 Motif Other DBs NCBI-GeneID:  5321 NCBI-ProteinID:  NP_077734 OMIM:  600522 HGNC:  9035 Ensembl:  ENSG00000116711 UniProt:  P47712 Structure PDB LinkDB All DBs Position 1:186828949..186988981 Genome browser AA seq 749 aa AA seqDB search MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRT RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEV PFIFNQVTEMVLEMSLEVCSCPDLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEG LHSARDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEE LENITTKHIVSNDSSDSDDESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFN TREGRAGKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDV KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN KLPFPKIDPYVFDREGLKECYVFKPKNPDMEKDCPTIIHFVLANINFRKYRAPGVPRETE EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRR QNPSRCSVSLSNVEARRFFNKEFLSKPKA NT seq 2250 nt NT seq  +upstreamnt  +downstreamnt atgtcatttatagatccttaccagcacattatagtggagcaccagtattcccacaagttt acggtagtggtgttacgtgccaccaaagtgacaaagggggcctttggtgacatgcttgat actccagatccctatgtggaactttttatctctacaacccctgacagcaggaagagaaca agacatttcaataatgacataaaccctgtgtggaatgagacctttgaatttattttggat cctaatcaggaaaatgttttggagattacgttaatggatgccaattatgtcatggatgaa actctagggacagcaacatttactgtatcttctatgaaggtgggagaaaagaaagaagtt ccttttattttcaaccaagtcactgaaatggttctagaaatgtctcttgaagtttgctca tgcccagacctacgatttagtatggctctgtgtgatcaggagaagactttcagacaacag agaaaagaacacataagggagagcatgaagaaactcttgggtccaaagaatagtgaagga ttgcattctgcacgtgatgtgcctgtggtagccatattgggttcaggtgggggtttccga gccatggtgggattctctggtgtgatgaaggcattatacgaatcaggaattctggattgt gctacctacgttgctggtctttctggctccacctggtatatgtcaaccttgtattctcac cctgattttccagagaaagggccagaggagattaatgaagaactaatgaaaaatgttagc cacaatccccttttacttctcacaccacagaaagttaaaagatatgttgagtctttatgg aagaagaaaagctctggacaacctgtcacctttactgatatctttgggatgttaatagga gaaacactaattcataatagaatgaatactactctgagcagtttgaaggaaaaagttaat actgcacaatgccctttacctcttttcacctgtcttcatgtcaaacctgacgtttcagag ctgatgtttgcagattgggttgaatttagtccatacgaaattggcatggctaaatatggt acttttatggctcccgacttatttggaagcaaattttttatgggaacagtcgttaagaag tatgaagaaaaccccttgcatttcttaatgggtgtctggggcagtgccttttccatattg ttcaacagagttttgggcgtttctggttcacaaagcagaggctccacaatggaggaagaa ttagaaaatattaccacaaagcatattgtgagtaatgatagctcggacagtgatgatgaa tcacacgaacccaaaggcactgaaaatgaagatgctggaagtgactatcaaagtgataat caagcaagttggattcatcgtatgataatggccttggtgagtgattcagctttattcaat accagagaaggacgtgctgggaaggtacacaacttcatgctgggcttgaatctcaataca tcttatccactgtctcctttgagtgactttgccacacaggactcctttgatgatgatgaa ctggatgcagctgtagcagatcctgatgaatttgagcgaatatatgagcctctggatgtc aaaagtaaaaagattcatgtagtggacagtgggctcacatttaacctgccgtatcccttg atactgagacctcagagaggggttgatctcataatctcctttgacttttctgcaaggcca agtgactctagtcctccgttcaaggaacttctacttgcagaaaagtgggctaaaatgaac aagctcccctttccaaagattgatccttatgtgtttgatcgggaagggctgaaggagtgc tatgtctttaaacccaagaatcctgatatggagaaagattgcccaaccatcatccacttt gttctggccaacatcaacttcagaaagtacagggctccaggtgttccaagggaaactgag gaagagaaagaaatcgctgactttgatatttttgatgacccagaatcaccattttcaacc ttcaattttcaatatccaaatcaagcattcaaaagactacatgatcttatgcacttcaat actctgaacaacattgatgtgataaaagaagccatggttgaaagcattgaatatagaaga cagaatccatctcgttgctctgtttcccttagtaatgttgaggcaagaagatttttcaac aaggagtttctaagtaaacccaaagcatag

Homo sapiens (human): 8605 Help Entry 8605              CDS       T01001                                  Symbol PLA2G4C, CPLA2-gamma Name (RefSeq) phospholipase A2 group IVC   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     8605 (PLA2G4C)    00565 Ether lipid metabolism     8605 (PLA2G4C)    00590 Arachidonic acid metabolism     8605 (PLA2G4C)    00591 Linoleic acid metabolism     8605 (PLA2G4C)    00592 alpha-Linolenic acid metabolism     8605 (PLA2G4C)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     8605 (PLA2G4C)    04014 Ras signaling pathway     8605 (PLA2G4C)    04370 VEGF signaling pathway     8605 (PLA2G4C)    04072 Phospholipase D signaling pathway     8605 (PLA2G4C)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     8605 (PLA2G4C)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     8605 (PLA2G4C)    04664 Fc epsilon RI signaling pathway     8605 (PLA2G4C)    04666 Fc gamma R-mediated phagocytosis     8605 (PLA2G4C)   09152 Endocrine system    04912 GnRH signaling pathway     8605 (PLA2G4C)    04913 Ovarian steroidogenesis     8605 (PLA2G4C)    04921 Oxytocin signaling pathway     8605 (PLA2G4C)   09153 Circulatory system    04270 Vascular smooth muscle contraction     8605 (PLA2G4C)   09156 Nervous system    04724 Glutamatergic synapse     8605 (PLA2G4C)    04726 Serotonergic synapse     8605 (PLA2G4C)    04730 Long-term depression     8605 (PLA2G4C)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     8605 (PLA2G4C)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     8605 (PLA2G4C) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      8605 (PLA2G4C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B Motif Other DBs NCBI-GeneID:  8605 NCBI-ProteinID:  NP_003697 OMIM:  603602 HGNC:  9037 Ensembl:  ENSG00000105499 UniProt:  Q9UP65 LinkDB All DBs Position 19:complement(48047846..48110817) Genome browser AA seq 541 aa AA seqDB search MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEADEAPVVAVLGSGGGLRAHIACL GVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTNDGDMEALEADLKHRFTRQEWDLAKSL QKTIQAARSENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQ PSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWG SALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPPPED EGGEPEHTWLTEMLENWTRTSLEKQEQPHEDPERKGSLSNLMDFVKKTGICASKWEWGTT HNFLYKHGGIRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFET IRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILKGETGPVVMHFPLFNIDACGGDIE AWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAGLYYPKDSARSCCL A NT seq 1626 nt NT seq  +upstreamnt  +downstreamnt atgggaagctctgaagtttccataattcctgggctccagaaagaagaaaaggcggccgtg gagagacgaagacttcatgtgctgaaagctctgaagaagctaaggattgaggctgatgag gccccagttgttgctgtgctgggctcaggcggaggactgcgggctcacattgcctgcctt ggggtcctgagtgagatgaaagaacagggcctgttggatgccgtcacgtacctcgcaggg gtctctggatccacttgggcaatatcttctctctacaccaatgatggtgacatggaagct ctcgaggctgacctgaaacatcgatttacccgacaggagtgggacttggctaagagccta cagaaaaccatccaagcagcgaggtctgagaattactctctgaccgacttctgggcctac atggttatctctaagcaaaccagagaactgccggagtctcatttgtccaatatgaagaag cccgtggaagaagggacactaccctacccaatatttgcagccattgacaatgacctgcaa ccttcctggcaggaggcaagagcaccagagacctggttcgagttcacccctcaccacgct ggcttctctgcactgggggcctttgtttccataacccacttcggaagcaaattcaagaag ggaagactggtcagaactcaccctgagagagacctgactttcctgagaggtttatgggga agtgctcttggtaacactgaagtcattagggaatacatttttgaccagttaaggaatctg accctgaaaggtttatggagaagggctgttgctaatgctaaaagcattggacaccttatt tttgcccgattactgaggctgcaagaaagttcacaaggggaacatcctcccccagaagat gaaggcggtgagcctgaacacacctggctgactgagatgctcgagaattggaccaggacc tccctggaaaagcaggagcagccccatgaggaccccgaaaggaaaggctcactcagtaac ttgatggattttgtgaagaaaacaggcatttgcgcttcaaagtgggaatgggggaccact cacaacttcctgtacaaacacggtggcatccgggacaagataatgagcagccggaagcac ctccacctggtggatgctggtttagccatcaacactcccttcccactcgtgctgcccccg acgcgggaggttcacctcatcctctccttcgacttcagtgccggagatcctttcgagacc atccgggctaccactgactactgccgccgccacaagatcccctttccccaagtagaagag gctgagctggatttgtggtccaaggcccccgccagctgctacatcctgaaaggagaaact ggaccagtggtgatgcattttcccctgttcaacatagatgcctgtggaggtgatattgag gcatggagtgacacatacgacacattcaagcttgctgacacctacactctagatgtggtg gtgctactcttggcattagccaagaagaatgtcagggaaaacaagaagaagatccttaga gagttgatgaacgtggccgggctctactacccgaaggatagtgcccgaagttgctgcttg gcatag

Homo sapiens (human): 8681 Help Entry 8681              CDS       T01001                                  Symbol JMJD7-PLA2G4B, HsT16992, cPLA2-beta Name (RefSeq) JMJD7-PLA2G4B readthrough   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04010   MAPK signaling pathway hsa04014   Ras signaling pathway hsa04072   Phospholipase D signaling pathway hsa04217   Necroptosis hsa04270   Vascular smooth muscle contraction hsa04370   VEGF signaling pathway hsa04611   Platelet activation hsa04664   Fc epsilon RI signaling pathway hsa04666   Fc gamma R-mediated phagocytosis hsa04724   Glutamatergic synapse hsa04726   Serotonergic synapse hsa04730   Long-term depression hsa04750   Inflammatory mediator regulation of TRP channels hsa04912   GnRH signaling pathway hsa04913   Ovarian steroidogenesis hsa04921   Oxytocin signaling pathway hsa05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     8681 (JMJD7-PLA2G4B)    00565 Ether lipid metabolism     8681 (JMJD7-PLA2G4B)    00590 Arachidonic acid metabolism     8681 (JMJD7-PLA2G4B)    00591 Linoleic acid metabolism     8681 (JMJD7-PLA2G4B)    00592 alpha-Linolenic acid metabolism     8681 (JMJD7-PLA2G4B)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     8681 (JMJD7-PLA2G4B)    04014 Ras signaling pathway     8681 (JMJD7-PLA2G4B)    04370 VEGF signaling pathway     8681 (JMJD7-PLA2G4B)    04072 Phospholipase D signaling pathway     8681 (JMJD7-PLA2G4B)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     8681 (JMJD7-PLA2G4B)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     8681 (JMJD7-PLA2G4B)    04664 Fc epsilon RI signaling pathway     8681 (JMJD7-PLA2G4B)    04666 Fc gamma R-mediated phagocytosis     8681 (JMJD7-PLA2G4B)   09152 Endocrine system    04912 GnRH signaling pathway     8681 (JMJD7-PLA2G4B)    04913 Ovarian steroidogenesis     8681 (JMJD7-PLA2G4B)    04921 Oxytocin signaling pathway     8681 (JMJD7-PLA2G4B)   09153 Circulatory system    04270 Vascular smooth muscle contraction     8681 (JMJD7-PLA2G4B)   09156 Nervous system    04724 Glutamatergic synapse     8681 (JMJD7-PLA2G4B)    04726 Serotonergic synapse     8681 (JMJD7-PLA2G4B)    04730 Long-term depression     8681 (JMJD7-PLA2G4B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     8681 (JMJD7-PLA2G4B)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     8681 (JMJD7-PLA2G4B) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      8681 (JMJD7-PLA2G4B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Cupin_8 PLA2_B cPLA2_C2 C2 Motif Other DBs NCBI-GeneID:  8681 NCBI-ProteinID:  NP_001185517 HGNC:  34449 Ensembl:  ENSG00000168970 UniProt:  P0C869 LinkDB All DBs Position 15:41828092..41848143 Genome browser AA seq 893 aa AA seqDB search MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRT CLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ SLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGT FRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGL RELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAM TSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKN KLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHG QNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRL PESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPST AGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEP HLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQGSGGHPRRRQLGR NT seq 2682 nt NT seq  +upstreamnt  +downstreamnt atggcggaggcggctttggaagccgtgcggagcgagttacgagaattcccggccgctgca agggagctctgcgtgcctcttgctgtgccctacctggacaaacccccaactccgctccac ttctaccgggactgggtctgccccaacaggccgtgcattatccgcaacgctctgcagcac tggccggccctccagaagtggtccctcccctatttcagagccacagtgggctccacagag gtgagtgtggccgtgaccccagatggttacgcggatgccgtgagaggggatcgcttcatg atgccagctgagcgccgcctgcccctgagcttcgtgctggatgtgctggagggccgggcc cagcaccctggagtcctctatgtgcagaagcagtgctccaacctgcccagcgagctgccc cagctgctgcctgatctggaatcccatgtgccctgggcctccgaagccctgggaaagatg cccgatgctgtgaacttctggctgggggaggcggctgcagtgacttctttgcacaaggac cactatgagaacctctactgcgtggtctcaggagagaagcatttcctgttccatccgccc agcgaccggcccttcatcccctatgagctgtacacgccggcaacctaccagctaactgaa gagggcacctttaaggtggtggatgaagaggccatggagaaggcagaggtgtccaggacc tgcctgctcacggttcgtgtcctgcaggcccatcgcctaccctctaaggacctagtgacc ccctctgactgctacgtgactctctggctgcccacggcctgcagccacaggctccagaca cgcacggtcaagaacagcagtagccctgtctggaaccagagctttcacttcaggatccac aggcagctcaagaatgtcatggaactgaaagtctttgaccaggacctggtgaccggagat gaccctgtgttgtcagtactgtttgatgcggggactctgcgggctggggagttccggcgc gagagcttctcactgagccctcagggtgaggggcgcctggaagttgaatttcgcctgcag agtctggctgaccgtggcgagtggctcgtcagcaatggcgttctggtggcccgggagctc tcctgcttgcacgttcaactggaggagacaggagaccagaagtcctcagagcacagagtt cagcttgtggttcctgggtcctgtgagggtccgcaggaggcctctgtgggcactggcacc ttccgcttccactgcccagcctgctgggagcaggagctgagtattcgcctgcaggatgcc cccgaggagcaactaaaggcgccactgagtgccctgccctctggtcaagtggtgaggctt gtcttccccacgtcccaggagcccctgatgagagtggagctgaaaaaagaagcaggactg agggagctggccgtgcgactgggcttcgggccctgtgcagaggagcaggccttcctgagc aggaggaagcaggtggtggccgcggccttgaggcaggccctgcagctggacggagacctg caggaggatgagatcccagtggtagctattatggccactggtggtgggatccgggcaatg acttccctgtatgggcagctggctggcctgaaggagctgggcctcttggattgcgtctcc tacatcaccggggcctcgggctccacctgggccttggccaacctttatgaggacccagag tggtctcagaaggacctggcagggcccactgagttgctgaagacccaggtgaccaagaac aagctgggtgtgctggcccccagccagctgcagcggtaccggcaggagctggccgagcgt gcccgcttgggctacccaagctgcttcaccaacctgtgggccctcatcaacgaggcgctg ctgcatgatgagccccatgatcacaagctctcagatcaacgggaggccctgagtcatggc cagaaccctctgcccatctactgtgccctcaacaccaaagggcagagcctgaccactttt gaatttggggagtggtgcgagttctctccctacgaggtcggcttccccaagtacggggcc ttcatcccctctgagctctttggctccgagttctttatggggcagctgatgaagaggctt cctgagtcccgcatctgcttcttagaaggtatctggagcaacctgtatgcagccaacctc caggacagcttatactgggcctcagagcccagccagttctgggaccgctgggtcaggaac caggccaacctggacaaggagcaggtcccccttctgaagatagaagaaccaccctcaaca gccggcaggatagctgagtttttcaccgatcttctgacgtggcgtccactggcccaggcc acacataatttcctgcgtggcctccatttccacaaagactactttcagcatcctcacttc tccacatggaaagctaccactctggatgggctccccaaccagctgacaccctcggagccc cacctgtgcctgctggatgttggctacctcatcaataccagctgcctgcccctcctgcag cccactcgggacgtggacctcatcctgtcattggactacaacctccacggagccttccag gggtccggcggacacccgaggaggcggcagctggggaggtga

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