Homo sapiens (human): 10220
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Entry
10220 CDS
T01001
Symbol
GDF11, BMP-11, BMP11, VHO
Name
(RefSeq) growth differentiation factor 11
KO
K22679
growth differentiation factor 11
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
Disease
H02640
Vertebral hypersegmentation and orofacial anomalies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
10220 (GDF11)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
10220 (GDF11)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Transforming growth factors (RSTK binding)
10220 (GDF11)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
10220
NCBI-ProteinID:
NP_005802
OMIM:
603936
HGNC:
4216
Ensembl:
ENSG00000135414
UniProt:
O95390
Structure
PDB
PDBj
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All DBs
Position
12:55743122..55757264
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AA seq
407 aa
AA seq
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MVLAAPLLLGFLLLALELRPRGEAAEGPAAAAAAAAAAAAAGVGGERSSRPAPSVAPEPD
GCPVCVWRQHSRELRLESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILDLHDFQ
GDALQPEDFLEEDEYHATTETVISMAQETDPAVQTDGSPLCCHFHFSPKVMFTKVLKAQL
WVYLRPVPRPATVYLQILRLKPLTGEGTAGGGGGGRRHIRIRSLKIELHSRSGHWQSIDF
KQVLHSWFRQPQSNWGIEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENTKRSRRNL
GLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQ
QANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atggtgctcgcggccccgctgctgctgggcttcctgctcctcgccctggagctgcggccc
cggggggaggcggccgagggccccgcggcggcggcggcggcggcggcggcggcggcagcg
gcgggggtcgggggggagcgctccagccggccagccccgtccgtggcgcccgagccggac
ggctgccccgtgtgcgtttggcggcagcacagccgcgagctgcgcctagagagcatcaag
tcgcagatcttgagcaaactgcggctcaaggaggcgcccaacatcagccgcgaggtggtg
aagcagctgctgcccaaggcgccgccgctgcagcagatcctggacctacacgacttccag
ggcgacgcgctgcagcccgaggacttcctggaggaggacgagtaccacgccaccaccgag
accgtcattagcatggcccaggagacggacccagcagtacagacagatggcagccctctc
tgctgccattttcacttcagccccaaggtgatgttcacaaaggtactgaaggcccagctg
tgggtgtacctacggcctgtaccccgcccagccacagtctacctgcagatcttgcgacta
aaacccctaactggggaagggaccgcagggggagggggcggaggccggcgtcacatccgt
atccgctcactgaagattgagctgcactcacgctcaggccattggcagagcatcgacttc
aagcaagtgctacacagctggttccgccagccacagagcaactggggcatcgagatcaac
gcctttgatcccagtggcacagacctggctgtcacctccctggggccgggagccgagggg
ctgcatccattcatggagcttcgagtcctagagaacacaaaacgttcccggcggaacctg
ggtctggactgcgacgagcactcaagcgagtcccgctgctgccgatatcccctcacagtg
gactttgaggctttcggctgggactggatcatcgcacctaagcgctacaaggccaactac
tgctccggccagtgcgagtacatgttcatgcaaaaatatccgcatacccatttggtgcag
caggccaatccaagaggctctgctgggccctgttgtacccccaccaagatgtccccaatc
aacatgctctacttcaatgacaagcagcagattatctacggcaagatccctggcatggtg
gtggatcgctgtggctgctcttaa
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