Homo sapiens (human): 10269
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Entry
10269 CDS
T01001
Symbol
ZMPSTE24, FACE-1, FACE1, HGPS, PRO1, RSDM1, STE24, Ste24p
Name
(RefSeq) zinc metallopeptidase STE24
KO
K06013
STE24 endopeptidase [EC:
3.4.24.84
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00900
Terpenoid backbone biosynthesis
Disease
H00663
Restrictive dermopathy
H00665
Mandibuloacral dysplasia
H02677
Progeroid laminopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
10269 (ZMPSTE24)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
10269 (ZMPSTE24)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
10269 (ZMPSTE24)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.84 Ste24 endopeptidase
10269 (ZMPSTE24)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M48: Ste24 endopeptidase family
10269 (ZMPSTE24)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
10269 (ZMPSTE24)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M48_N
Peptidase_M48
Motif
Other DBs
NCBI-GeneID:
10269
NCBI-ProteinID:
NP_005848
OMIM:
606480
HGNC:
12877
Ensembl:
ENSG00000084073
UniProt:
O75844
Structure
PDB
LinkDB
All DBs
Position
1:40258236..40294180
Genome browser
AA seq
475 aa
AA seq
DB search
MGMWASLDALWEMPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELGQIMD
SETFEKSRLYQLDKSTFSFWSGLYSETEGTLILLFGGIPYLWRLSGRFCGYAGFGPEYEI
TQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNQQTLGFFMKDAIKKFVVTQCILLP
VSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKEEIEV
MAKSIDFPLTKVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVLNKDIQEDSGM
EPRNEEEGNSEEIKAKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCF
FLFAVLIGRKELFAAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADA
FAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSMWHYSHPPLLERLQALKTMKQH
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
atggggatgtgggcatcgctggacgctttgtgggagatgccggccgagaagcgtatcttc
ggggccgtgctgctcttttcctggacagtgtatctttgggagaccttcctagcacagcgg
cagagaaggatatataaaacaacaactcatgtaccaccggagttaggacagatcatggat
tctgaaacatttgagaaatctcgactctatcaactggataaaagcactttcagcttctgg
tcaggactctattcagagactgaaggcactcttattcttctctttggaggaataccttat
ctctggagactttctggacggttctgtggttatgctggctttggaccagaatatgagatc
actcagtccctggtgtttctgctgttggctacacttttcagtgcattgactggtttgcca
tggagtctttataatacttttgtgatagaagaaaaacatggcttcaatcaacagactttg
gggttcttcatgaaagatgcaatcaagaaatttgttgtgactcagtgtattttgttgcct
gtgtcttcacttctactttacattattaaaattgggggtgactatttttttatttatgcc
tggctgttcacattagttgtgtctctggttcttgtcacaatctatgctgattatattgcc
cctttatttgacaaattcacacctctgcctgagggaaagcttaaagaagaaattgaagta
atggcaaagagtattgactttcctttgacgaaggtgtatgttgtggaaggatctaaacgc
tcttcccacagcaatgcttatttttatggcttcttcaagaacaagcgaatagttttgttt
gacactctactagaagagtactctgtactaaacaaagacatccaggaggattctggcatg
gaaccccgcaatgaggaagaagggaacagtgaagaaataaaagctaaagttaaaaataag
aaacaaggatgtaaaaatgaggaggtactcgctgtactaggccatgaactggggcactgg
aagttgggacatacagtcaaaaatatcattattagccagatgaattctttcctgtgtttt
tttttatttgctgtattaattggtcgaaaggagctttttgctgcatttggtttttatgat
agccaacccactcttattggactattgatcatcttccagtttattttttcaccttacaat
gaggttctttctttttgcctaacagtcctaagccgcagatttgagtttcaagctgatgca
tttgccaagaaacttgggaaggctaaagacttatattctgctttaatcaaacttaacaaa
gataacttgggattccctgtttctgactggttgttctcaatgtggcattattctcatcct
ccactgctagagagacttcaagctttgaaaactatgaagcaacactga
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