Homo sapiens (human): 10276
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Entry
10276 CDS
T01001
Symbol
NET1, ARHGEF8, NET1A
Name
(RefSeq) neuroepithelial cell-transforming gene 1 protein isoform 1
KO
K20683
Rho guanine nucleotide exchange factor 3/8
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
10276 (NET1)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
10276 (NET1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
SOS1_NGEF_PH
PH
PH_5
PH_13
IQ_SEC7_PH
Motif
Other DBs
NCBI-GeneID:
10276
NCBI-ProteinID:
NP_001040625
OMIM:
606450
HGNC:
14592
Ensembl:
ENSP00000347134.4
UniProt:
Q7Z628
Q5SQI5
Structure
PDB
PDBj
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All DBs
Position
10:5412557..5459056
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AA seq
596 aa
AA seq
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MEPELAAQKQPRPRRRSRRASGLSTEGATGPSADTSGSELDGRCSLRRGSSFTFLTPGPN
WDFTLKRKRREKDDDVVSLSSLDLKEPSNKRVRPLARVTSLANLISPVRNGAVRRFGQTI
QSFTLRGDHRSPASAQKFSSRSTVPTPAKRRSSALWSEMLDITMKESLTTREIRRQEAIY
EMSRGEQDLIEDLKLARKAYHDPMLKLSIMSEEELTHIFGDLDSYIPLHEDLLTRIGEAT
KPDGTVEQIGHILVSWLPRLNAYRGYCSNQLAAKALLDQKKQDPRVQDFLQRCLESPFSR
KLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPDVQLLEDAILIIQGVLSDINLKKGES
ECQYYIDKLEYLDEKQRDPRIEASKVLLCHGELRSKSGHKLYIFLFQDILVLTRPVTRNE
RHSYQVYRQPIPVQELVLEDLQDGDVRMGGSFRGAFSNSEKAKNIFRIRFHDPSPAQSHT
LQANDVFHKQQWFNCIRAAIAPFQSAGSPPELQGLPELHEECEGNHPSARKLTAQRRAST
VSSVTQVEVDENAYRCGSGMQMAEDSKSLKTHQTQPGIRRARDKALSGGKRKETLV
NT seq
1791 nt
NT seq
+upstream
nt +downstream
nt
atggagcccgagctggcggctcagaagcagcctcgaccgcggaggcgaagccgccgggcc
tctgggctcagcacggagggagcgacggggccttcggccgacacctccgggtcggagctg
gacgggagatgttcccttcggagaggcagctccttcacattcttaacacctggccccaac
tgggacttcactttgaaaagaaaacgcagagagaaagatgatgatgttgtaagccttagc
agccttgatctgaaggagccaagcaataaaagagttcgacctctggctcgtgtcacgtcc
ttggcaaatttaatctctcctgtaagaaatggagctgtcagacgttttggtcaaacaata
cagtcatttacccttcgtggtgaccacagatccccagcctctgcccagaagttttctagc
aggtcaacagtcccaacacccgccaagagaaggagcagtgcactgtggtcagagatgctg
gacatcaccatgaaggagtctctcaccaccagggagatcagacggcaggaggcaatatat
gaaatgtcccgaggtgaacaggatttaattgaggatctcaaacttgcaagaaaggcctat
catgaccccatgttaaagttgtccatcatgtcagaagaggaactcacacatatatttggt
gatctggactcttacatacctctgcatgaagatttgttgacaagaataggagaagcaacc
aagcctgatggaacagtggagcagattggtcacattctcgtgagctggttaccgcgcttg
aatgcctacagaggttactgtagtaaccagctggcagccaaagctcttcttgatcaaaag
aaacaggatccaagagtccaagacttcctccagcgatgtctcgagtctcccttcagtcga
aaactagatctttggagtttcctagatatccctcgaagtcgcctagtcaaatacccttta
ctgttaaaagaaattcttaaacacactccaaaagagcaccctgatgttcagcttctggag
gatgctatattgataatacagggagtcctctctgatatcaacttgaagaaaggtgaatcc
gagtgccagtattacatcgacaagctggagtacctggatgaaaagcagagggaccccaga
atcgaagcgagcaaagtgctgctgtgccatggggagctgcggagcaagagtggacataaa
ctttacattttcctgtttcaagacatcttggttctgactcggcccgtcacacggaacgaa
cggcactcttaccaggtttaccggcagccaatcccagtccaagagctagtcctagaagac
ctgcaggatggagatgtgagaatgggaggctcctttcgaggagctttcagtaactcagag
aaagctaaaaatatctttagaattcgcttccatgacccctctccagcccagtctcacact
ctgcaagccaatgacgtgttccacaagcagcagtggttcaactgtattcgagcggccatt
gcccccttccagtcggcaggcagtccacctgagctgcagggcctgccggagctgcacgaa
gagtgtgaggggaaccacccctctgcgaggaaactcacagcccagaggagggcatccaca
gtttccagtgttactcaggtagaagttgatgaaaacgcttacagatgtggctctggcatg
cagatggcagaggacagcaagagcttaaagacacaccagacacagcccggcatccgaaga
gcgagggacaaagccctttctggtggcaaacggaaagagactttggtgtag
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