Homo sapiens (human): 10277
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Entry
10277 CDS
T01001
Symbol
UBE4B, E4, HDNB1, UBOX3, UFD2, UFD2A
Name
(RefSeq) ubiquitination factor E4B
KO
K10597
ubiquitin conjugation factor E4 B [EC:
2.3.2.27
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
hsa04141
Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
10277 (UBE4B)
04120 Ubiquitin mediated proteolysis
10277 (UBE4B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
10277 (UBE4B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
10277 (UBE4B)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
U-box type E3
10277 (UBE4B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ufd2P_core
U-box
Motif
Other DBs
NCBI-GeneID:
10277
NCBI-ProteinID:
NP_001099032
OMIM:
613565
HGNC:
12500
Ensembl:
ENSG00000130939
Pharos:
O95155
(Tbio)
UniProt:
O95155
Structure
PDB
PDBj
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All DBs
Position
1:10032958..10181239
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AA seq
1302 aa
AA seq
DB search
MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNM
TPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSLSRSQSMDIDGVSCEKSMSQV
DVDSGIENMEVDENDRREKRSLSDKEPSSGPEVSEEQALQLVCKIFRVSWKDRDRDVIFL
SSLSAQFKQNPKEVFSDFKDLIGQILMEVLMMSTQTRDENPFASLTATSQPIAAAARSPD
RNLLLNTGSNPGTSPMFCSVASFGASSLSSLYESSPAPTPSFWSSVPVMGPSLASPSRAA
SQLAVPSTPLSPHSAASGTAAGSQPSSPRYRPYTVTHPWASSGVSILSSSPSPPALASSP
QAVPASSSRQRPSSTGPPLPPASPSATSRRPSSLRISPSLGASGGASNWDSYSDHFTIET
CKETDMLNYLIECFDRVGIEEKKAPKMCSQPAVSQLLSNIRSQCISHTALVLQGSLTQPR
SLQQPSFLVPYMLCRNLPYGFIQELVRTTHQDEEVFKQIFIPILQGLALAAKECSLDSDY
FKYPLMALGELCETKFGKTHPVCNLVASLRLWLPKSLSPGCGRELQRLSYLGAFFSFSVF
AEDDVKVVEKYFSGPAITLENTRVVSQSLQHYLELGRQELFKILHSILLNGETREAALSY
MAAVVNANMKKAQMQTDDRLVSTDGFMLNFLWVLQQLSTKIKLETVDPTYIFHPRCRITL
PNDETRVNATMEDVNDWLTELYGDQPPFSEPKFPTECFFLTLHAHHLSILPSCRRYIRRL
RAIRELNRTVEDLKNNESQWKDSPLATRHREMLKRCKTQLKKLVRCKACADAGLLDESFL
RRCLNFYGLLIQLLLRILDPAYPDITLPLNSDVPKVFAALPEFYVEDVAEFLFFIVQYSP
QALYEPCTQDIVMFLVVMLCNQNYIRNPYLVAKLVEVMFMTNPAVQPRTQKFFEMIENHP
LSTKLLVPSLMKFYTDVEHTGATSEFYDKFTIRYHISTIFKSLWQNIAHHGTFMEEFNSG
KQFVRYINMLINDTTFLLDESLESLKRIHEVQEEMKNKEQWDQLPRDQQQARQSQLAQDE
RVSRSYLALATETVDMFHILTKQVQKPFLRPELGPRLAAMLNFNLQQLCGPKCRDLKVEN
PEKYGFEPKKLLDQLTDIYLQLDCARFAKAIADDQRSYSKELFEEVISKMRKAGIKSTIA
IEKFKLLAEKVEEIVAKNARAEIDYSDAPDEFRDPLMDTLMTDPVRLPSGTIMDRSIILR
HLLNSPTDPFNRQTLTESMLEPVPELKEQIQAWMREKQNSDH
NT seq
3909 nt
NT seq
+upstream
nt +downstream
nt
atggaggagctgagcgctgatgagattcgacggaggcgccttgcacgacttgctggtgga
cagacctctcagccaaccaccccactcacctctccccagagggagaaccctccggggcct
cccatagcggcatcagccccaggaccctctcagagtcttggtctcaatgtccacaacatg
accccagctacctccccaataggtgcatcaggagtagcccatcgaagccagagcagtgaa
ggagtcagttctctcagcagctcgccctctaatagccttgaaacgcaatctcagtctctc
tcacgttcccagagcatggatatcgatggtgtctcatgtgagaaaagcatgtcccaggtg
gatgtggattcaggaattgaaaacatggaggttgatgaaaatgatcgaagagaaaagcgg
agcctcagtgataaggagccttcctcgggccctgaagtgtctgaagagcaggccttacag
ctggtctgtaagatcttccgtgtctcttggaaggaccgggacagagatgtcatctttctt
tcttctctttctgcacagtttaagcagaacccaaaagaagtattctccgattttaaggac
ttgattggccagattttaatggaagtgctaatgatgtccactcagaccagagatgaaaac
ccatttgccagtctgacagccacatcacagccaattgctgcagcagcacggtcaccagac
agaaatctcttgctaaacactggctccaatccaggaacaagccccatgttctgcagcgtg
gcttcctttggtgccagctctttgtctagcctctatgaaagtagtccggctcccactccc
agtttctggagctctgttcccgtgatgggcccgtctcttgcctcaccttcccgtgcagcc
agccagttggctgtgccttccactcccctcagtcctcacagtgcagcctctggaactgct
gcgggaagccagccttcatccccgcggtatcgcccctacactgtcactcacccatgggcg
tcctcaggcgtctccattctgtcgagctccccaagtccccctgccctcgccagtagcccc
caagcagtgcccgccagcagttccagacagaggcccagcagcacgggtccacccctacca
cccgcctcacccagtgccacgagcagacgcccctcctccctgaggatctctcctagtttg
ggagcctctggtggagcaagtaattgggattcctacagtgaccatttcaccattgaaacc
tgcaaagagacagatatgctgaactacctcatcgagtgtttcgaccgagttggaatagag
gaaaaaaaagcaccaaagatgtgcagccagccagcagtcagccagcttctgagcaacatc
cgctcacagtgcatatcccatactgctttagtactacaaggctccctaacacagcccagg
tccttgcagcagccgtccttcctagtgccgtatatgctgtgtaggaatctcccatatggc
ttcattcaggaactggtgagaaccactcaccaggatgaagaagtgttcaagcagatattt
atccccattttacaaggcctggctcttgctgccaaagagtgctccctcgacagtgactac
tttaaataccccctcatggcactaggtgagctctgtgaaaccaagtttgggaagacacac
cctgtgtgcaatttggttgcttctttgcggttgtggttgccgaaatccttaagtcctggc
tgtgggcgggagctgcagagactctcttacttaggggctttctttagcttctcagtcttt
gcagaagatgatgttaaagtggttgaaaaatacttctcagggcctgccattaccctggaa
aacactcgtgtggttagccaatcattgcagcattacttagagctcggaaggcaagagctt
tttaagattctgcatagtattttgttaaatggcgaaacccgtgaggctgctctcagttac
atggcggctgtcgtcaatgccaatatgaagaaagcacagatgcagacagatgatagattg
gtgtctacagatggatttatgctgaatttcctttgggtactgcagcagctaagtacaaaa
atcaagttagaaacagttgatcccacgtatatttttcacccaagatgtcggattactctt
cccaatgatgagacgcgtgtgaatgcaacgatggaagatgtgaatgactggctgactgaa
ctctatggcgatcagcctccattttctgagccgaaattccctacggagtgcttctttctc
accctgcatgctcaccacctctctattctgcctagttgccgtcgctatatccgcagactc
cgggctatccgggagctcaatagaactgtagaagatttgaaaaataatgaaagccaatgg
aaagattccccactggcaactagacaccgcgaaatgctgaagcgctgtaaaactcagctt
aagaaactggtacggtgcaaggcctgtgctgatgctggcctacttgacgagagcttcctg
agaagatgtctgaatttttatggccttctcattcagctgctgctccgcatcctggacccc
gcatatcccgatataacactgcctttaaattcagatgtccccaaggtatttgcagcgttg
cctgagttttatgtagaagatgttgcagaatttttattttttattgtacaatactctccc
caggcgctttatgagccctgtactcaggatattgtgatgttccttgttgtgatgttgtgc
aaccagaactacatccgaaacccatatttggtggccaaactggtagaagtcatgtttatg
accaaccctgctgttcagccacgaacccagaagttttttgaaatgattgagaaccatcct
ctctccaccaagttgttggtaccttccctgatgaagttttatacagatgttgagcatacc
ggagccaccagtgagttttatgacaagttcacaattcgctatcatattagcaccattttt
aaaagcctttggcaaaacatagctcaccatggcacctttatggaggagttcaactccggg
aagcagtttgttcgctatataaacatgttgataaacgacacgacgtttttgctcgatgaa
agtctggagtctctgaagcgaatccatgaagtgcaggaagagatgaagaacaaagaacag
tgggaccagttgccccgggatcagcagcaggctcgtcagtctcagcttgctcaggatgag
cgtgtgtcccgctcttacctcgccctggccaccgaaaccgtggacatgttccacatcctc
acgaagcaggtccagaagcccttcctcagaccggagcttggaccccgattggctgcaatg
ctgaactttaatcttcagcaactttgtggccccaagtgccgtgacctgaaagttgaaaac
cctgagaaatacggctttgaaccaaagaagctgttggaccaactgacggatatttactta
cagctggactgtgctcggttcgcgaaagccattgctgacgaccagagatcctacagtaag
gaattgtttgaagaagttatttcaaagatgcggaaggcagggatcaaatccacaatagca
atagaaaaatttaagctgctcgccgagaaagtggaggagatagtggccaagaacgcacgc
gcagaaatcgactacagcgacgctcctgatgagttcagagaccctctgatggacaccctc
atgacagaccccgtgcggctgccctctggcaccatcatggaccgctccatcatcctgcgg
cacctgctcaactcccccacggaccccttcaaccggcagacgctgacagagagcatgctg
gaaccagtgccagaactgaaagagcagattcaggcgtggatgagagagaaacagaacagc
gatcactaa
DBGET
integrated database retrieval system