| Entry |
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| Symbol |
ERN2, IRE1-BETA, IRE1b, IRE2p, hIRE2p
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| Name |
(RefSeq) endoplasmic reticulum to nucleus signaling 2
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| KO |
| K11715 | serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-] |
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| Organism |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
10595 (ERN2)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
10595 (ERN2)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: Other
IRE family
10595 (ERN2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:complement(23690310..23713222)
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| AA seq |
926 aa
MASAVRGSRPWPRLGLQLQFAALLLGTLSPQVHTLRPENLLLVSTLDGSLHALSKQTGDL
KWTLRDDPVIEGPMYVTEMAFLSDPADGSLYILGTQKQQGLMKLPFTIPELVHASPCRSS
DGVFYTGRKQDAWFVVDPESGETQMTLTTEGPSTPRLYIGRTQYTVTMHDPRAPALRWNT
TYRRYSAPPMDGSPGKYMSHLASCGMGLLLTVDPGSGTVLWTQDLGVPVMGVYTWHQDGL
RQLPHLTLARDTLHFLALRWGHIRLPASGPRDTATLFSTLDTQLLMTLYVGKDETGFYVS
KALVHTGVALVPRGLTLAPADGPTTDEVTLQVSGEREGSPSTAVRYPSGSVALPSQWLLI
GHHELPPVLHTTMLRVHPTLGSGTAETRPPENTQAPAFFLELLSLSREKLWDSELHPEEK
TPDSYLGLGPQDLLAASLTAVLLGGWILFVMRQQQPQVVEKQQETPLAPADFAHISQDAQ
SLHSGASRRSQKRLQSPSKQAQPLDDPEAEQLTVVGKISFNPKDVLGRGAGGTFVFRGQF
EGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTERGPQFHYIALELCRASLQE
YVENPDLDRGGLEPEVVLQQLMSGLAHLHSLHIVHRDLKPGNILITGPDSQGLGRVVLSD
FGLCKKLPAGRCSFSLHSGIPGTEGWMAPELLQLLPPDSPTSAVDIFSAGCVFYYVLSGG
SHPFGDSLYRQANILTGAPCLAHLEEEVHDKVVARDLVGAMLSPLPQPRPSAPQVLAHPF
FWSRAKQLQFFQDVSDWLEKESEQEPLVRALEAGGCAVVRDNWHEHISMPLQTDLRKFRS
YKGTSVRDLLRAVRNKKHHYRELPVEVRQALGQVPDGFVQYFTNRFPRLLLHTHRAMRSC
ASESLFLPYYPPDSEARRPCPGATGR |
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| NT seq |
2781 nt +upstreamnt +downstreamnt
atggcgagtgcggtcagggggtcgaggccgtggccccggctggggctccagctccagttc
gcggcgctgctgctcgggacgctgagtccacaggttcatactctcaggccagagaacctc
ctgctggtgtccaccttggatggaagtctccacgcactaagcaagcagacaggggacctg
aagtggactctgagggatgatcccgtcatcgaaggaccaatgtacgtcacagaaatggcc
tttctctctgacccagcagatggcagcctgtacatcttggggacccaaaaacaacaggga
ttaatgaaactgccattcaccatccctgagctggttcatgcctctccctgccgcagctct
gatggggtcttctacacaggccggaagcaggatgcctggtttgtggtggaccctgagtca
ggggagacccagatgacactgaccacagagggtccctccaccccccgcctctacattggc
cgaacacagtatacggtcaccatgcatgacccaagagccccagccctgcgctggaacacc
acctaccgccgctactcagcgccccccatggatggctcacctgggaaatacatgagccac
ctggcgtcctgcgggatgggcctgctgctcactgtggacccaggaagcgggacggtgctg
tggacacaggacctgggcgtgcctgtgatgggcgtctacacctggcaccaggacggcctg
cgccagctgccgcatctcacgctggctcgagacactctgcatttcctcgccctccgctgg
ggccacatccgactgcctgcctcaggcccccgggacacagccaccctcttctctaccttg
gacacccagctgctaatgacgctgtatgtggggaaggatgaaactggcttctatgtctct
aaagcactggtccacacaggagtggccctggtgcctcgtggactgaccctggcccccgca
gatggccccaccacagatgaggtgacactccaagtctcaggagagcgagagggctcaccc
agcactgctgttagatacccctcaggcagtgtggccctcccaagccagtggctgctcatt
ggacaccacgagctacccccagtcctgcacaccaccatgctgagggtccatcccaccctg
gggagtggaactgcagagacaagacctccagagaatacccaggccccagccttcttcttg
gagctattgagcctgagccgagagaaactttgggactccgagctgcatccagaagaaaaa
actccagactcttacttggggctgggaccccaagacctgctggcagctagcctcactgct
gtcctcctgggagggtggattctctttgtgatgaggcagcaacagccgcaggtggtggag
aagcagcaggagacccccctggcacctgcagactttgctcacatctcccaggatgcccag
tccctgcactcgggggccagccggaggagccagaagaggcttcagagtccctcaaagcaa
gcccagccactcgacgaccctgaagctgagcaactcaccgtagtggggaagatttccttc
aatcccaaggacgtgctgggccgcggggcaggcgggactttcgttttccggggacagttt
gagggacgggcagtggctgtcaagcggctcctccgcgagtgctttggcctggttcggcgg
gaagttcaactgctgcaggagtctgacaggcaccccaacgtgctccgctacttctgcacc
gagcggggaccccagttccactacattgccctggagctctgccgggcctccttgcaggag
tacgtagaaaacccggacctggatcgcgggggtctggagcccgaggtcgtgctgcagcag
ctgatgtctggcctggcccacctgcactctttacacatagtgcaccgggacctgaagcca
ggaaatattctcatcaccgggcctgacagccagggcctgggcagagtggtgctctcagac
ttcggcctctgcaagaagctgcctgctggccgctgtagcttcagcctccactccggcatc
cccggcacggaaggctggatggcgcccgagcttctgcagctcctgccaccagacagtcct
accagcgctgtggacatcttctctgcaggctgcgtgttctactacgtgctttctggtggc
agccacccctttggagacagtctttatcgccaggcaaacatcctcacaggggctccctgt
ctggctcacctggaggaagaggtccacgacaaggtggttgcccgggacctggttggagcc
atgttgagcccactgccgcagccacgcccctctgccccccaggtgctggcccaccccttc
ttttggagcagagccaagcaactccagttcttccaggacgtcagtgactggctggagaag
gagtccgagcaggagcccctggtgagggcactggaggcgggaggctgcgcagtggtccgg
gacaactggcacgagcacatctccatgccgctgcagacagatctgagaaagttccggtcc
tataaggggacatcagtgcgagacctgctccgtgctgtgaggaacaagaagcaccactac
agggagctcccagttgaggtgcgacaggcactcggccaagtccctgatggcttcgtccag
tacttcacaaaccgcttcccacggctgctcctccacacgcaccgagccatgaggagctgc
gcctctgagagcctcttcctgccctactacccgccagactcagaggccaggaggccatgc
cctggggccacagggaggtga |
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