Homo sapiens (human): 10667
Help
Entry
10667 CDS
T01001
Symbol
FARS2, COXPD14, FARS1, HSPC320, PheRS, SPG77, mtPheRS
Name
(RefSeq) phenylalanyl-tRNA synthetase 2, mitochondrial
KO
K01889
phenylalanyl-tRNA synthetase alpha chain [EC:
6.1.1.20
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H00266
Hereditary spastic paraplegia
H00891
Combined oxidative phosphorylation deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
10667 (FARS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
10667 (FARS2)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
10667 (FARS2)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.20 phenylalanine---tRNA ligase
10667 (FARS2)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class II (U)
10667 (FARS2)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
10667 (FARS2)
Prokaryotic type
10667 (FARS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
tRNA-synt_2d
FDX-ACB
tRNA-synt_2
Motif
Other DBs
NCBI-GeneID:
10667
NCBI-ProteinID:
NP_001305801
OMIM:
611592
HGNC:
21062
Ensembl:
ENSG00000145982
UniProt:
O95363
Structure
PDB
PDBj
LinkDB
All DBs
Position
6:5249934..5771583
Genome browser
AA seq
451 aa
AA seq
DB search
MVGSALRRGAHAYVYLVSKASHISRGHQHQAWGSRPPAAECATQRAPGSVVELLGKSYPQ
DDHSNLTRKVLTRVGRNLHNQQHHPLWLIKERVKEHFYKQYVGRFGTPLFSVYDNLSPVV
TTWQNFDSLLIPADHPSRKKGDNYYLNRTHMLRAHTSAHQWDLLHAGLDAFLVVGDVYRR
DQIDSQHYPIFHQLEAVRLFSKHELFAGIKDGESLQLFEQSSRSAHKQETHTMEAVKLVE
FDLKQTLTRLMAHLFGDELEIRWVDCYFPFTHPSFEMEINFHGEWLEVLGCGVMEQQLVN
SAGAQDRIGWAFGLGLERLAMILYDIPDIRLFWCEDERFLKQFCVSNINQKVKFQPLSKY
PAVINDISFWLPSENYAENDFYDLVRTIGGDLVEKVDLIDKFVHPKTHKTSHCYRITYRH
MERTLSQREVRHIHQALQEAAVQLLGVEGRF
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggtgggctcagctctcaggagaggtgcccatgcatatgtctacctggtgagtaaggcc
agtcacatctccagaggccatcagcaccaggcctggggatcgaggcctcctgcagcagag
tgtgccacccaaagagctccaggcagtgtggtggagctgctgggcaaatcctaccctcag
gacgaccacagcaacctcacccggaaggtcctcaccagagttggcaggaacctgcacaac
cagcagcatcaccctctgtggctgatcaaggagagggtgaaggagcacttctacaagcag
tatgtgggccgctttgggaccccgttgttctcggtctacgacaacctttctccagtggtc
acgacctggcagaactttgacagcctgctcatcccagctgatcaccccagcaggaagaag
ggggacaactattacctgaatcggactcacatgctgagagcgcacacgtctgcacaccag
tgggacttgctgcacgcgggactggatgccttcctggtggtgggtgatgtctacaggcgt
gaccagatcgactcccagcactaccctattttccaccagctggaggccgtgcggctcttc
tccaagcatgagttatttgctggtataaaggatggagaaagcctgcagctctttgaacaa
agttctcgctctgcgcataaacaagagacacacaccatggaggccgtgaagcttgtagag
tttgatcttaagcaaacgcttaccaggctcatggcacatctttttggagatgagctggag
ataagatgggtagactgctacttcccttttacacatccttcctttgagatggagatcaac
tttcatggagaatggctggaagttcttggctgcggggtgatggaacaacaactggtcaat
tcagctggtgctcaagaccgaatcggctgggcttttggcctaggattagaaaggctagcc
atgatcctctacgacatccctgatatccgtctcttctggtgtgaggacgagcgcttcctg
aagcagttctgtgtatccaacattaatcagaaggtgaagtttcagcctcttagcaaatat
ccggctgtgatcaatgatatttcattctggttgccctctgagaattacgcagaaaatgat
ttctatgacttagtccgaacaattggaggagacctggtggaaaaggttgatctcatagac
aagtttgtacatccaaagacgcacaagaccagccactgctaccgcatcacgtaccgccac
atggaacggactctgtcccagagagaggtcaggcacatccaccaggccttgcaggaggct
gcagtccagctgttgggtgtggagggcaggttctga
DBGET
integrated database retrieval system
