Homo sapiens (human): 106821730
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Entry
106821730 CDS
T01001
Symbol
BUB1B-PAK6, PAK-5, PAK-6, PAK5, PAK6
Name
(RefSeq) serine/threonine-protein kinase PAK 6
KO
K05735
p21-activated kinase 6 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04014
Ras signaling pathway
hsa04360
Axon guidance
hsa04510
Focal adhesion
hsa04517
IgSF CAM signaling
hsa04660
T cell receptor signaling pathway
hsa04810
Regulation of actin cytoskeleton
hsa05170
Human immunodeficiency virus 1 infection
hsa05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
106821730 (BUB1B-PAK6)
04014 Ras signaling pathway
106821730 (BUB1B-PAK6)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
106821730 (BUB1B-PAK6)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
106821730 (BUB1B-PAK6)
09142 Cell motility
04810 Regulation of actin cytoskeleton
106821730 (BUB1B-PAK6)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
106821730 (BUB1B-PAK6)
09158 Development and regeneration
04360 Axon guidance
106821730 (BUB1B-PAK6)
09160 Human Diseases
09162 Cancer: specific types
05211 Renal cell carcinoma
106821730 (BUB1B-PAK6)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
106821730 (BUB1B-PAK6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
106821730 (BUB1B-PAK6)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
106821730 (BUB1B-PAK6)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: STE group
STE20 family
106821730 (BUB1B-PAK6)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
Kinase-like
ABC1
Pkinase_fungal
CIS_ATPase_hel
Motif
Other DBs
NCBI-GeneID:
106821730
NCBI-ProteinID:
NP_001122100
HGNC:
52276
UniProt:
Q9NQU5
Structure
PDB
PDBj
LinkDB
All DBs
Position
15:40217428..40277487
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AA seq
681 aa
AA seq
DB search
MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRIT
RVQLQPMKTVVRGSAMPVDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDE
HWATDPDMYLQSPQSERTDPHGLYLSCNGGTPAGHKQMPWPEPQSPRVLPNGLAAKAQSL
GPAEFQGASQRCLQLGACLQSSPPGASPPTGTNRHGMKAAKHGSEEARPQSCLVGSATGR
PGGEGSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPPPQSKPNSSFRPPQKDNPP
SLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPAGSPRTWHAQIS
TSNLYLPQDPTVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGI
VCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVL
MEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRV
KLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPP
YFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQ
TGLPECLVPLIQLYRKQTSTC
NT seq
2046 nt
NT seq
+upstream
nt +downstream
nt
atgttccgcaagaaaaagaagaaacgccctgagatctcagcgccacagaacttccagcac
cgtgtccacacctccttcgaccccaaagaaggcaagtttgtgggcctccccccacaatgg
cagaacatcctggacacactgcggcgccccaagcccgtggtggacccttcgcgaatcaca
cgggtgcagctccagcccatgaagacagtggtgcggggcagcgcgatgcctgtggatggc
tacatctcggggctgctcaacgacatccagaagttgtcagtcatcagctccaacaccctg
cgtggccgcagccccaccagccggcggcgggcacagtccctggggctgctgggggatgag
cactgggccaccgacccagacatgtacctccagagcccccagtctgagcgcactgacccc
cacggcctctacctcagctgcaacgggggcacaccagcaggccacaagcagatgccgtgg
cccgagccacagagcccacgggtcctgcccaatgggctggctgcaaaggcacagtccctg
ggccccgccgagtttcagggtgcctcgcagcgctgtctgcagctgggtgcctgcctgcag
agctccccaccaggagcctcgccccccacgggcaccaataggcatggaatgaaggctgcc
aagcatggctctgaggaggcccggccacagtcctgcctggtgggctcagccacaggcagg
ccaggtggggaaggcagccctagccctaagacccgggagagcagcctgaagcgcaggcta
ttccgaagcatgttcctgtccactgctgccacagcccctccaagcagcagcaagccaggc
cctccaccacagagcaagcccaactcctctttccgaccgccgcagaaagacaacccccca
agcctggtggccaaggcccagtccttgccctcggaccagccggtggggaccttcagccct
ctgaccacttcggataccagcagcccccagaagtccctccgcacagccccggccacaggc
cagcttccaggccggtcttccccagcgggatccccccgcacctggcacgcccagatcagc
accagcaacctgtacctgccccaggaccccacggttgccaagggtgccctggctggtgag
gacacaggtgttgtgacacatgagcagttcaaggctgcgctcaggatggtggtggaccag
ggtgacccccggctgctgctggacagctacgtgaagattggcgagggctccaccggcatc
gtctgcttggcccgggagaagcactcgggccgccaggtggccgtcaagatgatggacctc
aggaagcagcagcgcagggagctgctcttcaacgaggtggtgatcatgcgggactaccag
cacttcaacgtggtggagatgtacaagagctacctggtgggcgaggagctgtgggtgctc
atggagttcctgcagggaggagccctcacagacatcgtctcccaagtcaggctgaatgag
gagcagattgccactgtgtgtgaggctgtgctgcaggccctggcctacctgcatgctcag
ggtgtcatccaccgggacatcaagagtgactccatcctgctgaccctcgatggcagggtg
aagctctcggacttcggattctgtgctcagatcagcaaagacgtccctaagaggaagtcc
ctggtgggaaccccctactggatggctcctgaagtgatctccaggtctttgtatgccact
gaggtggatatctggtctctgggcatcatggtgattgagatggtagatggggagccaccg
tacttcagtgactccccagtgcaagccatgaagaggctccgggacagccccccacccaag
ctgaaaaactctcacaaggtctccccagtgctgcgagacttcctggagcggatgctggtg
cgggacccccaagagagagccacagcccaggagctcctagaccaccccttcctgctgcag
acagggctacctgagtgcctggtgcccctgatccagctctaccgaaagcagacctccacc
tgctga
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