Homo sapiens (human): 10768 Help Entry 10768             CDS       T01001                                  Symbol AHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA Name (RefSeq) adenosylhomocysteinase like 1   KO K01251   adenosylhomocysteinase [EC:3.13.2.1] Organism hsa  Homo sapiens (human) Pathway hsa00270   Cysteine and methionine metabolism hsa00670   One carbon pool by folate hsa01100   Metabolic pathways Module hsa_M00035   Methionine degradation Network nt06030  Methionine metabolism   Element N01607   Methionine degradation Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     10768 (AHCYL1)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     10768 (AHCYL1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hsa01009]     10768 (AHCYL1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     10768 (AHCYL1) Enzymes [BR:hsa01000]  3. Hydrolases   3.13  Acting on carbon-sulfur bonds    3.13.2  Thioether and trialkylsulfonium hydrolases     3.13.2.1  adenosylhomocysteinase      10768 (AHCYL1) Protein phosphatases and associated proteins [BR:hsa01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      10768 (AHCYL1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    10768 (AHCYL1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C KARI_N THF_DHG_CYH_C Shikimate_DH NAD_binding_7 AlaDh_PNT_C TrkA_N Glu_dehyd_C SR-25 Motif Other DBs NCBI-GeneID:  10768 NCBI-ProteinID:  NP_006612 OMIM:  607826 HGNC:  344 Ensembl:  ENSG00000168710 UniProt:  O43865 A0A024R0A8 Structure PDBPDBj LinkDB All DBs Position 1:109984765..110023742 Genome browser AA seq 530 aa AA seqDB search MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY NT seq 1593 nt NT seq  +upstreamnt  +downstreamnt atgtcgatgcctgacgcgatgccgctgcccggggtcggggaggagctgaagcaggccaag gagatcgaggacgccgagaagtactccttcatggccaccgtcaccaaggcgcccaagaag caaatccagtttgctgatgacatgcaggagttcaccaaattccccaccaaaactggccga agatctttgtctcgctcgatctcacagtcctccactgacagctacagttcagctgcatcc tacacagatagctctgatgatgaggtttctccccgagagaagcagcaaaccaactccaag ggcagcagcaatttctgtgtgaagaacatcaagcaggcagaatttggacgccgggagatt gagattgcagagcaagacatgtctgctctgatttcactcaggaaacgtgctcagggggag aagcccttggctggtgctaaaatagtgggctgtacacacatcacagcccagacagcggtg ttgattgagacactctgtgccctgggggctcagtgccgctggtctgcttgtaacatctac tcaactcagaatgaagtagctgcagcactggctgaggctggagttgcagtgttcgcttgg aagggcgagtcagaagatgacttctggtggtgtattgaccgctgtgtgaacatggatggg tggcaggccaacatgatcctggatgatgggggagacttaacccactgggtttataagaag tatccaaacgtgtttaagaagatccgaggcattgtggaagagagcgtgactggtgttcac aggctgtatcagctctccaaagctgggaagctctgtgttccggccatgaacgtcaatgat tctgttaccaaacagaagtttgataacttgtactgctgccgagaatccattttggatggc ctgaagaggaccacagatgtgatgtttggtgggaaacaagtggtggtgtgtggctatggt gaggtaggcaagggctgctgtgctgctctcaaagctcttggagcaattgtctacattacc gaaatcgaccccatctgtgctctgcaggcctgcatggatgggttcagggtggtaaagcta aatgaagtcatccggcaagtcgatgtcgtaataacttgcacaggaaataagaatgtagtg acacgggagcacttggatcgcatgaaaaacagttgtatcgtatgcaatatgggccactcc aacacagaaatcgatgtgaccagcctccgcactccggagctgacgtgggagcgagtacgt tctcaggtggaccatgtcatctggccagatggcaaacgagttgtcctcctggcagagggt cgtctactcaatttgagctgctccacagttcccacctttgttctgtccatcacagccaca acacaggctttggcactgatagaactctataatgcacccgaggggcgatacaagcaggat gtgtacttgcttcctaagaaaatggatgaatacgttgccagcttgcatctgccatcattt gatgcccaccttacagagctgacagatgaccaagcaaaatatctgggactcaacaaaaat gggccattcaaacctaattattacagatactaa

Homo sapiens (human): 191 Help Entry 191               CDS       T01001                                  Symbol AHCY, SAHH, adoHcyase Name (RefSeq) adenosylhomocysteinase   KO K01251   adenosylhomocysteinase [EC:3.13.2.1] Organism hsa  Homo sapiens (human) Pathway hsa00270   Cysteine and methionine metabolism hsa00670   One carbon pool by folate hsa01100   Metabolic pathways Module hsa_M00035   Methionine degradation Network nt06030  Methionine metabolism   Element N01607   Methionine degradation Disease H00184   Hypermethioninemia Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     191 (AHCY)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     191 (AHCY)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hsa01009]     191 (AHCY)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     191 (AHCY) Enzymes [BR:hsa01000]  3. Hydrolases   3.13  Acting on carbon-sulfur bonds    3.13.2  Thioether and trialkylsulfonium hydrolases     3.13.2.1  adenosylhomocysteinase      191 (AHCY) Protein phosphatases and associated proteins [BR:hsa01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      191 (AHCY) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    191 (AHCY) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C KARI_N TrkA_N ELFV_dehydrog 3HCDH_N Motif Other DBs NCBI-GeneID:  191 NCBI-ProteinID:  NP_000678 OMIM:  180960 HGNC:  343 Ensembl:  ENSG00000101444 UniProt:  P23526 A0A384MTQ3 Structure PDBPDBj LinkDB All DBs Position 20:complement(34231981..34311836) Genome browser AA seq 432 aa AA seqDB search MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS CDGPFKPDHYRY NT seq 1299 nt NT seq  +upstreamnt  +downstreamnt atgtctgacaaactgccctacaaagtcgccgacatcggcctggctgcctggggacgcaag gccctggacattgctgagaacgagatgccgggcctgatgcgtatgcgggagcggtactcg gcctccaagccactgaagggcgcccgcatcgctggctgcctgcacatgaccgtggagacg gccgtcctcattgagaccctcgtcaccctgggtgctgaggtgcagtggtccagctgcaac atcttctccacccaggaccatgcggcggctgccattgccaaggctggcattccggtgtat gcctggaagggcgaaacggacgaggagtacctgtggtgcattgagcagaccctgtacttc aaggacgggcccctcaacatgattctggacgacgggggcgacctcaccaacctcatccac accaagtacccgcagcttctgccaggcatccgaggcatctctgaggagaccacgactggg gtccacaacctctacaagatgatggccaatgggatcctcaaggtgcctgccatcaatgtc aatgactccgtcaccaagagcaagtttgacaacctctatggctgccgggagtccctcata gatggcatcaagcgggccacagatgtgatgattgccggcaaggtagcggtggtagcaggc tatggtgatgtgggcaagggctgtgcccaggccctgcggggtttcggagcccgcgtcatc atcaccgagattgaccccatcaacgcactgcaggctgccatggagggctatgaggtgacc accatggatgaggcctgtcaggagggcaacatctttgtcaccaccacaggctgtattgac atcatccttggccggcactttgagcagatgaaggatgatgccattgtgtgtaacattgga cactttgacgtggagatcgatgtcaagtggctcaacgagaacgccgtggagaaggtgaac atcaagccgcaggtggaccggtatcggttgaagaatgggcgccgcatcatcctgctggcc gagggtcggctggtcaacctgggttgtgccatgggccaccccagcttcgtgatgagtaac tccttcaccaaccaggtgatggcgcagatcgagctgtggacccatccagacaagtacccc gttggggttcatttcctgcccaagaagctggatgaggcagtggctgaagcccacctgggc aagctgaatgtgaagttgaccaagctaactgagaagcaagcccagtacctgggcatgtcc tgtgatggccccttcaagccggatcactaccgctactga

Homo sapiens (human): 23382 Help Entry 23382             CDS       T01001                                  Symbol AHCYL2, ADOHCYASE3, IRBIT2 Name (RefSeq) adenosylhomocysteinase like 2   KO K01251   adenosylhomocysteinase [EC:3.13.2.1] Organism hsa  Homo sapiens (human) Pathway hsa00270   Cysteine and methionine metabolism hsa00670   One carbon pool by folate hsa01100   Metabolic pathways Module hsa_M00035   Methionine degradation Network nt06030  Methionine metabolism   Element N01607   Methionine degradation Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09105 Amino acid metabolism    00270 Cysteine and methionine metabolism     23382 (AHCYL2)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     23382 (AHCYL2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hsa01009]     23382 (AHCYL2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     23382 (AHCYL2) Enzymes [BR:hsa01000]  3. Hydrolases   3.13  Acting on carbon-sulfur bonds    3.13.2  Thioether and trialkylsulfonium hydrolases     3.13.2.1  adenosylhomocysteinase      23382 (AHCYL2) Protein phosphatases and associated proteins [BR:hsa01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      23382 (AHCYL2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    23382 (AHCYL2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AdoHcyase AdoHcyase_NAD 2-Hacid_dh_C Shikimate_DH THF_DHG_CYH_C NAD_binding_7 KARI_N TrkA_N AlaDh_PNT_C SR-25 Motif Other DBs NCBI-GeneID:  23382 NCBI-ProteinID:  NP_056143 OMIM:  616520 HGNC:  22204 Ensembl:  ENSG00000158467 UniProt:  Q96HN2 Structure PDBPDBj LinkDB All DBs Position 7:129225030..129430211 Genome browser AA seq 611 aa AA seqDB search MSVQVVSAAAAAKVPEVELKDLSPSEAESQLGLSTAAVGAMAPPAGGGDPEAPAPAAERP PVPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK KQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNS KGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTA VLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVE GWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVN DSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYV TEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGH SNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITA TTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNK NGPFKPNYYRY NT seq 1836 nt NT seq  +upstreamnt  +downstreamnt atgtcggtgcaggttgtgtcagccgcggctgccgccaaggtgcctgaggtggagctgaag gacctgagcccctccgaggcggagtcgcaactaggactgagcacggccgccgtgggcgcc atggcccccccggcgggcggtggagaccctgaggctccagctcccgccgcggagcggccc ccggtccccggcccgggctcggggcccgccgccgctctcagccccgccgccgggaaggtg cctcaggcgtcggccatgaagcggagcgacccacatcaccagcaccagcggcaccgcgac ggcggcgaggccctggtcagccccgacggcaccgtcaccgaggcgccgcgcacagtcaag aagcagatccagtttgctgaccagaagcaagaattcaacaaacgtcccaccaaaattgga cgtcgctctttgtctcgttccatttctcagtcatctactgacagctacagctcagcggct tcatatacagatagctctgatgatgagacatcgcccagggacaagcagcaaaagaactct aagggaagcagtgacttctgtgttaagaacatcaaacaggcagagtttggacgaagagaa attgaaattgctgaacaagaaatgcctgcattgatggctttgaggaagagagctcaagga gaaaagcctttggctggagccaaaatcgtgggttgcacacacatcactgctcagactgct gtgcttatggaaactctgggtgctctgggggcccagtgccgatgggctgcctgcaacatc tattccactctcaatgaagtggctgctgctctagcagaaagtggatttcctgtttttgcc tggaagggagagtcagaagatgacttttggtggtgtatcgatagatgtgtgaatgtggag ggctggcagccaaacatgatcttggatgatggaggggatcttacccactggatttataaa aagtatcccaacatgtttaagaaaatcaagggcatagtagaggagagtgttactggagtt cacaggctgtaccaactgtccaaagctgggaagctgtgtgttccagccatgaatgtcaat gactcagtcaccaaacagaaatttgacaacctctactgttgccgtgaatcaattcttgat ggacttaaaaggacaacagacatgatgtttggtggaaagcaagtggtagtctgtggctat ggagaggtggggaaagggtgctgtgctgccctgaaagccatgggctccattgtgtatgta actgaaattgaccccatctgtgccctgcaagcctgtatggatggatttcgactggtgaaa ttaaatgaggtcatccgacaagtggacattgttattacctgtacaggtaacaagaatgtg gtaaccagagagcacttggaccgtatgaagaatagctgcatcgtttgtaacatgggacat tccaacacagagattgacgtggcgagtctgcggacaccagaactgacctgggagcgagtg agatctcaagttgaccatgtgatatggcctgatggcaagaggatagtactgctggcagag ggccgcctgctgaaccttagctgctccacagtgcctacatttgtgctctcaatcactgct actactcaggctcttgccttgatagagctttacaatgctcctgagggtcgctataagcag gatgtctacctgttgcccaagaagatggatgagtatgtggccagcctacacctgcctacc tttgatgcccacttgacagagctgacagatgaacaggccaagtatctgggactcaacaag aatgggcccttcaagcctaattactacaggtattaa

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