Homo sapiens (human): 10785
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Entry
10785 CDS
T01001
Symbol
WDR4, GAMOS6, MIGSB, TRM82, TRMT82, Wuho, hWH
Name
(RefSeq) WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit
KO
K15443
tRNA (guanine-N(7)-)-methyltransferase subunit TRM82
Organism
hsa
Homo sapiens (human)
Disease
H01722
Galloway-Mowat syndrome
H02132
Microcephaly syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
10785 (WDR4)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
tRNA modification factors
Methyltransferases
10785 (WDR4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Beta-prop_THOC3
WD40_WDHD1_1st
WD40
Beta-prop_WDR3_1st
Beta-prop_WDR5
WD40_Prp19
Beta-prop_TEP1_2nd
WD40_CDC20-Fz
Beta-prop_EML_2
WDR55
EIF3I
Beta-prop_CAF1B_HIR1
Beta-prop_WDR75_1st
Beta-prop_WDR3_2nd
Beta-prop_WDR36-Utp21_2nd
WD40_MABP1-WDR62_2nd
Beta-prop_TEP1_C
WD40_Gbeta
Beta-prop_EIPR1
Motif
Other DBs
NCBI-GeneID:
10785
NCBI-ProteinID:
NP_061139
OMIM:
605924
HGNC:
12756
Ensembl:
ENSG00000160193
UniProt:
P57081
Structure
PDB
PDBj
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All DBs
Position
21:complement(42843094..42892998)
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AA seq
412 aa
AA seq
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MAGSVGLALCGQTLVVRGGSRFLATSIASSDDDSLFIYDCSAAEKKSQENKGEDAPLDQG
SGAILASTFSKSGSYFALTDDSKRLILFRTKPWQCLSVRTVARRCTALTFIASEEKVLVA
DKSGDVYSFSVLEPHGCGRLELGHLSMLLDVAVSPDDRFILTADRDEKIRVSWAAAPHSI
ESFCLGHTEFVSRISVVPTQPGLLLSSSGDGTLRLWEYRSGRQLHCCHLASLQELVDPQA
PQKFAASRIAFWCQENCVALLCDGTPVVYIFQLDARRQQLVYRQQLAFQHQVWDVAFEET
QGLWVLQDCQEAPLVLYRPVGDQWQSVPESTVLKKVSGVLRGNWAMLEGSAGADASFSSL
YKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHAKKMRPGEATLSC
NT seq
1239 nt
NT seq
+upstream
nt +downstream
nt
atggcgggctctgtgggactggcgttgtgcgggcagacgttggtggtgcggggcggcagc
cgattcctggccacctccatagcaagcagtgatgatgacagcctcttcatctatgactgc
agtgctgcagaaaagaagtcacaagaaaataaaggggaggacgcgcccttggaccagggg
agcggtgcgattctggcgtccaccttctccaagtctggcagctattttgctttaaccgat
gacagtaagcgtctgattcttttccgtacaaaaccatggcaatgtctgagtgtcaggacc
gtggcaaggaggtgtacagccctgactttcatagcctcggaggagaaggtcttggtggcc
gacaagtctggagacgtctactccttttcggtgctggagccacacgggtgtggccgtcta
gagctggggcacctgtctatgctgttagatgtggctgtgagtcctgatgaccgcttcatc
ctcactgccgaccgggacgagaagatccgagtcagctgggccgcggcgccccatagcatc
gagtccttctgcttggggcacacagagtttgtgagccgtatctccgtggtgccaactcag
cccgggctgcttctgtcctcctctggggacggcaccctgaggctctgggagtacaggagc
ggccgccagctgcactgctgtcacctggccagtctgcaggagctggtggacccccaggcc
ccccagaagtttgccgcgtccaggattgcattctggtgccaggagaactgcgtggcgctc
ctgtgcgacggcactcctgtggtctacatcttccagctggacgcccgcagacagcagttg
gtgtacaggcagcagctggcgttccagcaccaagtgtgggacgtggctttcgaggagacc
caggggctgtgggtgctccaggactgccaggaagcccccctggtgctctacaggcctgtg
ggcgaccagtggcagtctgttcctgagagcaccgtgttaaagaaagtctctggtgttctt
cgtgggaactgggccatgctggaaggctctgccggcgcagacgccagcttcagcagtctc
tacaaggccacgttcgacaacgtgacctcctacctgaagaagaaagaggagagactgcag
cagcagctagagaagaagcagcggcgccggagtcccccgcctgggcccgacgggcatgcc
aagaagatgagaccgggggaggcgacgctaagttgctga
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