Homo sapiens (human): 10891
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Entry
10891 CDS
T01001
Symbol
PPARGC1A, LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1
Name
(RefSeq) PPARG coactivator 1 alpha
KO
K07202
alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha
Organism
hsa
Homo sapiens (human)
Pathway
hsa04152
AMPK signaling pathway
hsa04211
Longevity regulating pathway
hsa04371
Apelin signaling pathway
hsa04714
Thermogenesis
hsa04910
Insulin signaling pathway
hsa04920
Adipocytokine signaling pathway
hsa04922
Glucagon signaling pathway
hsa04931
Insulin resistance
hsa04936
Alcoholic liver disease
hsa05016
Huntington disease
Network
nt06461
Huntington disease
Element
N00981
Mutation-caused aberrant Htt to CREB-mediated transcription
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
10891 (PPARGC1A)
04152 AMPK signaling pathway
10891 (PPARGC1A)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
10891 (PPARGC1A)
04922 Glucagon signaling pathway
10891 (PPARGC1A)
04920 Adipocytokine signaling pathway
10891 (PPARGC1A)
09149 Aging
04211 Longevity regulating pathway
10891 (PPARGC1A)
09159 Environmental adaptation
04714 Thermogenesis
10891 (PPARGC1A)
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
10891 (PPARGC1A)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
10891 (PPARGC1A)
04931 Insulin resistance
10891 (PPARGC1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
hsa03029
]
10891 (PPARGC1A)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Coactivators
10891 (PPARGC1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RRM_1
Tox-ODYAM1
Motif
Other DBs
NCBI-GeneID:
10891
NCBI-ProteinID:
NP_037393
OMIM:
604517
HGNC:
9237
Ensembl:
ENSG00000109819
UniProt:
Q9UBK2
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:complement(23792021..24472905)
Genome browser
AA seq
798 aa
AA seq
DB search
MAWDMCNQDSESVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSD
QSEIISNQYNNEPSNIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTD
NEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHNHRIRTNP
AIVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCTSKK
KSHTQSQSQHLQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTP
PHKANQDNPFRASPKLKSSCKTVVPPPSKKPRYSESSGTQGNNSTKKGPEQSELYAQLSK
SSVLTGGHEERKTKRPSLRLFGDHDYCQSINSKTEILINISQELQDSRQLENKDVSSDWQ
GQICSSTDSDQCYLRETLEASKQVSPCSTRKQLQDQEIRAELNKHFGHPSQAVFDDEADK
TGELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLSYPWDGTQSYSLFNVSPSC
SSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSC
YYYESSHYRHRTHRNSPLYVRSRSRSPYSRRPRYDSYEEYQHERLKREEYRREYEKRESE
RAKQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFI
TYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKY
DSLDFDSLLKEAQRSLRR
NT seq
2397 nt
NT seq
+upstream
nt +downstream
nt
atggcgtgggacatgtgcaaccaggactctgagtctgtatggagtgacatcgagtgtgct
gctctggttggtgaagaccagcctctttgcccagatcttcctgaacttgatctttctgaa
ctagatgtgaacgacttggatacagacagctttctgggtggactcaagtggtgcagtgac
caatcagaaataatatccaatcagtacaacaatgagccttcaaacatatttgagaagata
gatgaagagaatgaggcaaacttgctagcagtcctcacagagacactagacagtctccct
gtggatgaagacggattgccctcatttgatgcgctgacagatggagacgtgaccactgac
aatgaggctagtccttcctccatgcctgacggcacccctccaccccaggaggcagaagag
ccgtctctacttaagaagctcttactggcaccagccaacactcagctaagttataatgaa
tgcagtggtctcagtacccagaaccatgcaaatcacaatcacaggatcagaacaaaccct
gcaattgttaagactgagaattcatggagcaataaagcgaagagtatttgtcaacagcaa
aagccacaaagacgtccctgctcggagcttctcaaatatctgaccacaaacgatgaccct
cctcacaccaaacccacagagaacagaaacagcagcagagacaaatgcacctccaaaaag
aagtcccacacacagtcgcagtcacaacacttacaagccaaaccaacaactttatctctt
cctctgaccccagagtcaccaaatgaccccaagggttccccatttgagaacaagactatt
gaacgcaccttaagtgtggaactctctggaactgcaggcctaactccacccaccactcct
cctcataaagccaaccaagataacccttttagggcttctccaaagctgaagtcctcttgc
aagactgtggtgccaccaccatcaaagaagcccaggtacagtgagtcttctggtacacaa
ggcaataactccaccaagaaagggccggagcaatccgagttgtatgcacaactcagcaag
tcctcagtcctcactggtggacacgaggaaaggaagaccaagcggcccagtctgcggctg
tttggtgaccatgactattgccagtcaattaattccaaaacagaaatactcattaatata
tcacaggagctccaagactctagacaactagaaaataaagatgtctcctctgattggcag
gggcagatttgttcttccacagattcagaccagtgctacctgagagagactttggaggca
agcaagcaggtctctccttgcagcacaagaaaacagctccaagaccaggaaatccgagcc
gagctgaacaagcacttcggtcatcccagtcaagctgtttttgacgacgaagcagacaag
accggtgaactgagggacagtgatttcagtaatgaacaattctccaaactacctatgttt
ataaattcaggactagccatggatggcctgtttgatgacagcgaagatgaaagtgataaa
ctgagctacccttgggatggcacgcaatcctattcattgttcaatgtgtctccttcttgt
tcttcttttaactctccatgtagagattctgtgtcaccacccaaatccttattttctcaa
agaccccaaaggatgcgctctcgttcaaggtccttttctcgacacaggtcgtgttcccga
tcaccatattccaggtcaagatcaaggtctccaggcagtagatcctcttcaagatcctgc
tattactatgagtcaagccactacagacaccgcacgcaccgaaattctcccttgtatgtg
agatcacgttcaagatcgccctacagccgtcggcccaggtatgacagctacgaggaatat
cagcacgagaggctgaagagggaagaatatcgcagagagtatgagaagcgagagtctgag
agggccaagcaaagggagaggcagaggcagaaggcaattgaagagcgccgtgtgatttat
gtcggtaaaatcagacctgacacaacacggacagaactgagggaccgttttgaagttttt
ggtgaaattgaggagtgcacagtaaatctgcgggatgatggagacagctatggtttcatt
acctaccgttatacctgtgatgcttttgctgctcttgaaaatggatacactttgcgcagg
tcaaacgaaactgactttgagctgtacttttgtggacgcaagcaatttttcaagtctaac
tatgcagacctagattcaaactcagatgactttgaccctgcttccaccaagagcaagtat
gactctctggattttgatagtttactgaaagaagctcagagaagcttgcgcaggtaa
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integrated database retrieval system
