Homo sapiens (human): 11040
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Entry
11040 CDS
T01001
Symbol
PIM2
Name
(RefSeq) Pim-2 proto-oncogene, serine/threonine kinase
KO
K08806
proto-oncogene serine/threonine-protein kinase Pim-2 [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa05200
Pathways in cancer
hsa05221
Acute myeloid leukemia
Network
nt06219
JAK-STAT signaling (cancer)
nt06275
Acute myeloid leukemia
Element
N00054
Duplication or mutation-activated FLT3 to Jak-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
11040 (PIM2)
09162 Cancer: specific types
05221 Acute myeloid leukemia
11040 (PIM2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
11040 (PIM2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
11040 (PIM2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
PIM family [OT]
11040 (PIM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
11040
NCBI-ProteinID:
NP_006866
OMIM:
300295
HGNC:
8987
Ensembl:
ENSG00000102096
UniProt:
Q9P1W9
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:complement(48913182..48919024)
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AA seq
311 aa
AA seq
DB search
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAI
KVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPL
PAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKL
IDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFER
DQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKG
GPAPLAWSLLP
NT seq
936 nt
NT seq
+upstream
nt +downstream
nt
atgttgaccaagcctctacaggggcctcccgcgccccccgggacccccacgccgccgcca
ggaggcaaggatcgggaagcgttcgaggccgagtatcgactcggccccctcctgggtaag
gggggctttggcaccgtcttcgcaggacaccgcctcacagatcgactccaggtggccatc
aaagtgattccccggaatcgtgtgctgggctggtcccccttgtcagactcagtcacatgc
ccactcgaagtcgcactgctatggaaagtgggtgcaggtggtgggcaccctggcgtgatc
cgcctgcttgactggtttgagacacaggagggcttcatgctggtcctcgagcggcctttg
cccgcccaggatctctttgactatatcacagagaagggcccactgggtgaaggcccaagc
cgctgcttctttggccaagtagtggcagccatccagcactgccattcccgtggagttgtc
catcgtgacatcaaggatgagaacatcctgatagacctacgccgtggctgtgccaaactc
attgattttggttctggtgccctgcttcatgatgaaccctacactgactttgatgggaca
agggtgtacagccccccagagtggatctctcgacaccagtaccatgcactcccggccact
gtctggtcactgggcatcctcctctatgacatggtgtgtggggacattccctttgagagg
gaccaggagattctggaagctgagctccacttcccagcccatgtctccccagactgctgt
gccctaatccgccggtgcctggcccccaaaccttcttcccgaccctcactggaagagatc
ctgctggacccctggatgcaaacaccagccgaggatgtacccctcaacccctccaaagga
ggccctgcccctttggcctggtccttgctaccctaa
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