KEGG   Homo sapiens (human): 11060
Entry
11060             CDS       T01001                                 
Symbol
WWP2, AIP2, WWp2-like
Name
(RefSeq) WW domain containing E3 ubiquitin protein ligase 2
  KO
K05630  NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    11060 (WWP2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    11060 (WWP2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     11060 (WWP2)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   11060 (WWP2)
SSDB
Motif
Pfam: HECT WW
Other DBs
NCBI-GeneID: 11060
NCBI-ProteinID: NP_001257383
OMIM: 602308
HGNC: 16804
Ensembl: ENSG00000198373
Pharos: O00308(Tbio)
UniProt: O00308
Structure
LinkDB
Position
16:69762332..69941739
AA seq 870 aa
MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
RLDLPPYKSYEQLREKLLYAIEETEGFGQE
NT seq 2613 nt   +upstreamnt  +downstreamnt
atggcatctgccagctctagccgggcaggagtggccctgccttttgagaagtctcagctc
actttgaaagtggtgtccgcaaagcccaaggtgcataatcgtcaacctcgaattaactcc
tacgtggaggtggcggtggatggactccccagtgagaccaagaagactgggaagcgcatt
gggagctctgagcttctctggaatgagatcatcattttgaatgtcacggcacagagtcat
ttagatttaaaggtctggagctgccataccttgagaaatgaactgctaggcaccgcatct
gtcaacctctccaacgtcttgaagaacaatgggggcaaaatggagaacatgcagctgacc
ctgaacctgcagacggagaacaaaggcagcgttgtctcaggcggagagctgacaattttc
ctggacgggccaactgttgatctgggaaatgtgcctaatggcagtgccctgacagatgga
tcacagctgccttcgagagactccagtggaacagcagtagctccagagaaccggcaccag
ccccccagcacaaactgctttggtggaagatcccggacgcacagacattcgggtgcttca
gccagaacaaccccagcaaccggcgagcaaagccccggtgctcggagccggcaccgccag
cccgtcaagaactcaggccacagtggcttggccaatggcacagtgaatgatgaacccaca
acagccactgatcccgaagaaccttccgttgttggtgtgacgtccccacctgctgcaccc
ttgagtgtgaccccgaatcccaacacgacttctctccctgccccagccacaccggctgaa
ggagaggaacccagcacttcgggtacacagcagctcccagcggctgcccaggcccccgac
gctctgcctgctggatgggaacagcgagagctgcccaacggacgtgtctattatgttgac
cacaataccaagaccaccacctgggagcggccccttcctccaggctgggaaaaacgcaca
gatccccgaggcaggttttactatgtggatcacaatactcggaccaccacctggcagcgt
ccgaccgcggagtacgtgcgcaactatgagcagtggcagtcgcagcggaatcagctccag
ggggccatgcagcacttcagccaaagattcctctaccagtcttcgagtgcttcgactgac
catgatcccctgggccccctccctcctggctgggagaagagacaggacaatggacgggtg
tattacgtgaaccataacactcgcacgacccagtgggaggatccccggacccaggggatg
atccaggaaccagctctgcccccaggatgggagatgaaatacaccagcgagggggtgcga
tactttgtggaccacaatacccgcaccaccacctttaaggatcctcgcccggggtttgag
tcggggacgaagcaaggttcccctggtgcttatgaccgcagttttcggtggaagtatcac
cagttccgtttcctctgccattcaaatgccctacctagccacgtgaagatcagcgtttcc
aggcagacgcttttcgaagattccttccaacagatcatgaacatgaaaccctatgacctg
cgccgccggctctacatcatcatgcgtggcgaggagggcctggactatgggggcatcgcc
agagagtggtttttcctcctgtctcatgaggtgctcaaccctatgtattgtttatttgaa
tatgccggaaagaacaattactgcctgcagatcaaccccgcctcctccatcaacccggac
cacctcacctactttcgctttataggcagattcatcgccatggcgctgtaccatggaaag
ttcatcgacacgggcttcaccctccctttctacaagcggatgctcaataagagaccaacc
ctgaaagacctggagtccattgaccctgagttctacaactccattgtctggatcaaagag
aacaacctggaagaatgtggcctggagctgtacttcatccaggacatggagatactgggc
aaggtgacgacccacgagctgaaggagggcggcgagagcatccgggtcacagaggagaac
aaggaagagtacatcatgctgctgactgactggcgtttcacccgaggcgtggaagagcag
accaaagccttcctggatggcttcaacgaggtggccccgctggagtggctgcgctacttt
gacgagaaagagctggagctgatgctgtgcggcatgcaggagatagacatgagcgactgg
cagaagagcaccatctaccggcactacaccaagaacagcaagcagatccagtggttctgg
caggtggtgaaggagatggacaacgagaagaggatccggctgctgcagtttgtcaccggt
acctgccgcctgcccgtcgggggatttgccgaactcatcggtagcaacggaccacagaag
ttttgcattgacaaagttggcaaggaaacctggctgcccagaagccacacctgcttcaac
cgtctggatcttccaccctacaagagctacgaacagctgagagagaagctgctgtatgcc
attgaggagaccgagggctttggacaggagtaa

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