Homo sapiens (human): 11060
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Entry
11060 CDS
T01001
Symbol
WWP2, AIP2, WWp2-like
Name
(RefSeq) WW domain containing E3 ubiquitin protein ligase 2
KO
K05630
NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:
2.3.2.26
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
11060 (WWP2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
11060 (WWP2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
11060 (WWP2)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
HECT type E3
11060 (WWP2)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
Motif
Other DBs
NCBI-GeneID:
11060
NCBI-ProteinID:
NP_001257383
OMIM:
602308
HGNC:
16804
Ensembl:
ENSG00000198373
Pharos:
O00308
(Tbio)
UniProt:
O00308
Structure
PDB
PDBj
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Position
16:69762332..69941739
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AA seq
870 aa
AA seq
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MASASSSRAGVALPFEKSQLTLKVVSAKPKVHNRQPRINSYVEVAVDGLPSETKKTGKRI
GSSELLWNEIIILNVTAQSHLDLKVWSCHTLRNELLGTASVNLSNVLKNNGGKMENMQLT
LNLQTENKGSVVSGGELTIFLDGPTVDLGNVPNGSALTDGSQLPSRDSSGTAVAPENRHQ
PPSTNCFGGRSRTHRHSGASARTTPATGEQSPGARSRHRQPVKNSGHSGLANGTVNDEPT
TATDPEEPSVVGVTSPPAAPLSVTPNPNTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPD
ALPAGWEQRELPNGRVYYVDHNTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQR
PTAEYVRNYEQWQSQRNQLQGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRV
YYVNHNTRTTQWEDPRTQGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFE
SGTKQGSPGAYDRSFRWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDL
RRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPD
HLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKE
NNLEECGLELYFIQDMEILGKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQ
TKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFW
QVVKEMDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDKVGKETWLPRSHTCFN
RLDLPPYKSYEQLREKLLYAIEETEGFGQE
NT seq
2613 nt
NT seq
+upstream
nt +downstream
nt
atggcatctgccagctctagccgggcaggagtggccctgccttttgagaagtctcagctc
actttgaaagtggtgtccgcaaagcccaaggtgcataatcgtcaacctcgaattaactcc
tacgtggaggtggcggtggatggactccccagtgagaccaagaagactgggaagcgcatt
gggagctctgagcttctctggaatgagatcatcattttgaatgtcacggcacagagtcat
ttagatttaaaggtctggagctgccataccttgagaaatgaactgctaggcaccgcatct
gtcaacctctccaacgtcttgaagaacaatgggggcaaaatggagaacatgcagctgacc
ctgaacctgcagacggagaacaaaggcagcgttgtctcaggcggagagctgacaattttc
ctggacgggccaactgttgatctgggaaatgtgcctaatggcagtgccctgacagatgga
tcacagctgccttcgagagactccagtggaacagcagtagctccagagaaccggcaccag
ccccccagcacaaactgctttggtggaagatcccggacgcacagacattcgggtgcttca
gccagaacaaccccagcaaccggcgagcaaagccccggtgctcggagccggcaccgccag
cccgtcaagaactcaggccacagtggcttggccaatggcacagtgaatgatgaacccaca
acagccactgatcccgaagaaccttccgttgttggtgtgacgtccccacctgctgcaccc
ttgagtgtgaccccgaatcccaacacgacttctctccctgccccagccacaccggctgaa
ggagaggaacccagcacttcgggtacacagcagctcccagcggctgcccaggcccccgac
gctctgcctgctggatgggaacagcgagagctgcccaacggacgtgtctattatgttgac
cacaataccaagaccaccacctgggagcggccccttcctccaggctgggaaaaacgcaca
gatccccgaggcaggttttactatgtggatcacaatactcggaccaccacctggcagcgt
ccgaccgcggagtacgtgcgcaactatgagcagtggcagtcgcagcggaatcagctccag
ggggccatgcagcacttcagccaaagattcctctaccagtcttcgagtgcttcgactgac
catgatcccctgggccccctccctcctggctgggagaagagacaggacaatggacgggtg
tattacgtgaaccataacactcgcacgacccagtgggaggatccccggacccaggggatg
atccaggaaccagctctgcccccaggatgggagatgaaatacaccagcgagggggtgcga
tactttgtggaccacaatacccgcaccaccacctttaaggatcctcgcccggggtttgag
tcggggacgaagcaaggttcccctggtgcttatgaccgcagttttcggtggaagtatcac
cagttccgtttcctctgccattcaaatgccctacctagccacgtgaagatcagcgtttcc
aggcagacgcttttcgaagattccttccaacagatcatgaacatgaaaccctatgacctg
cgccgccggctctacatcatcatgcgtggcgaggagggcctggactatgggggcatcgcc
agagagtggtttttcctcctgtctcatgaggtgctcaaccctatgtattgtttatttgaa
tatgccggaaagaacaattactgcctgcagatcaaccccgcctcctccatcaacccggac
cacctcacctactttcgctttataggcagattcatcgccatggcgctgtaccatggaaag
ttcatcgacacgggcttcaccctccctttctacaagcggatgctcaataagagaccaacc
ctgaaagacctggagtccattgaccctgagttctacaactccattgtctggatcaaagag
aacaacctggaagaatgtggcctggagctgtacttcatccaggacatggagatactgggc
aaggtgacgacccacgagctgaaggagggcggcgagagcatccgggtcacagaggagaac
aaggaagagtacatcatgctgctgactgactggcgtttcacccgaggcgtggaagagcag
accaaagccttcctggatggcttcaacgaggtggccccgctggagtggctgcgctacttt
gacgagaaagagctggagctgatgctgtgcggcatgcaggagatagacatgagcgactgg
cagaagagcaccatctaccggcactacaccaagaacagcaagcagatccagtggttctgg
caggtggtgaaggagatggacaacgagaagaggatccggctgctgcagtttgtcaccggt
acctgccgcctgcccgtcgggggatttgccgaactcatcggtagcaacggaccacagaag
ttttgcattgacaaagttggcaaggaaacctggctgcccagaagccacacctgcttcaac
cgtctggatcttccaccctacaagagctacgaacagctgagagagaagctgctgtatgcc
attgaggagaccgagggctttggacaggagtaa
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