Homo sapiens (human): 1108
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Entry
1108 CDS
T01001
Symbol
CHD4, CHD-4, Mi-2b, Mi2-BETA, SIHIWES
Name
(RefSeq) chromodomain helicase DNA binding protein 4
KO
K11643
chromodomain-helicase-DNA-binding protein 4 [EC:5.6.2.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03082
ATP-dependent chromatin remodeling
hsa05165
Human papillomavirus infection
hsa05203
Viral carcinogenesis
Network
nt06166
Human papillomavirus (HPV)
nt06516
TNF signaling
Element
N00375
HPV E7 to TNF-IRF1 signaling pathway
Disease
H02328
Sifrim-Hitz-Weiss syndrome
H02616
Neurodevelopmental disorder with macrocephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09126 Chromosome
03082 ATP-dependent chromatin remodeling
1108 (CHD4)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
1108 (CHD4)
09172 Infectious disease: viral
05165 Human papillomavirus infection
1108 (CHD4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
1108 (CHD4)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Heterochromatin formation proteins
Other heterochromatin formation proteins
1108 (CHD4)
Chromatin remodeling factors
NuRD complex
1108 (CHD4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SNF2-rel_dom
CHDCT2
CHDII_SANT-like
Helicase_C
CHDNT
DUF1087
PHD
Chromo
ResIII
HDA2-3
PHD-1st_NSD
PHDvar_NSD
PHD_2
DEAD
Motif
Other DBs
NCBI-GeneID:
1108
NCBI-ProteinID:
NP_001264
OMIM:
603277
HGNC:
1919
Ensembl:
ENSG00000111642
Pharos:
Q14839
(Tbio)
UniProt:
Q14839
Structure
PDB
LinkDB
All DBs
Position
12:complement(6570082..6607379)
Genome browser
AA seq
1912 aa
AA seq
DB search
MASGLGSPSPCSAGSEEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKP
RDPKIPKSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKL
GPKKEKKSKSKRKEEEEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKA
FSQFVRPLIAAKNPKIAVSKMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESM
VTATEVAPPPPPVEVPIRKAKTKEGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIKLGG
FGSKRKRSSSEDDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVT
AVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEKEGIQ
WEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPL
PEIPNGEWLCPRCTCPALKGKVQKILIWKWGQPPSPTPVPRPPDADPNTPSPKPLEGRPE
RQFFVKWQGMSYWHCSWVSELQLELHCQVMFRNYQRKNDMDEPPSGDFGGDEEKSRKRKN
KDPKFAEMEERFYRYGIKPEWMMIHRILNHSVDKKGHVHYLIKWRDLPYDQASWESEDVE
IQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRKLERPPETPTVDPTVKYERQPEYLD
ATGGTLHPYQMEGLNWLRFSWAQGTDTILADEMGLGKTVQTAVFLYSLYKEGHSKGPFLV
SAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAIIRENEFSFEDNAIRGGKKASRMKKE
ASVKFHVLLTSYELITIDMAILGSIDWACLIVDEAHRLKNNQSKFFRVLNGYSLQHKLLL
TGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFADIAKEDQIKKLHDMLGPHMLRRLKA
DVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFEALNARGGGNQVSLLNVVMDLKKCCN
HPYLFPVAAMEAPKMPNGMYDGSALIRASGKLLLLQKMLKNLKEGGHRVLIFSQMTKMLD
LLEDFLEHEGYKYERIDGGITGNMRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADT
VIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKKKMMLTHLVVR
PGLGSKTGSMSKQELDDILKFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDR
NQDETEDTELQGMNEYLSSFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRH
HYEQQQEDLARNLGKGKRIRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDER
SEAPRRPSRKGLRNDKDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYGMPPQDAFT
TQWLVRDLRGKSEKEFKAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMS
LIRKKVQEFEHVNGRWSMPELAEVEENKKMSQPGSPSPKTPTPSTPGDTQPNTPAPVPPA
EDGIKIEENSLKEEESIEGEKEVKSTAPETAIECTQAPAPASEDEKVVVEPPEGEEKVEK
AEVKERTEEPMETEPKGAADVEKVEEKSAIDLTPIVVEDKEEKKEEEEKKEVMLQNGETP
KDLNDEKQKKNIKQRFMFNIADGGFTELHSLWQNEERAATVTKKTYEIWHRRHDYWLLAG
IINHGYARWQDIQNDPRYAILNEPFKGEMNRGNFLEIKNKFLARRFKLLEQALVIEEQLR
RAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKESMAGNKPANAVLHKVLKQLEEL
LSDMKADVTRLPATIARIPPVAVRLQMSERNILSRLANRAPEPTPQQVAQQQ
NT seq
5739 nt
NT seq
+upstream
nt +downstream
nt
atggcgtcgggcctgggctccccgtccccctgctcggcgggcagtgaggaggaggatatg
gatgcacttttgaacaacagcctgcccccaccccacccagaaaatgaagaggacccagaa
gaggatttgtcagaaacagagactccaaagctcaagaagaagaaaaagcctaagaaacct
cgggaccctaaaatccctaagagcaagcgccaaaaaaaggagcgtatgctcttatgccgg
cagctgggggacagctctggggaggggccagagtttgtggaggaggaggaagaggtggct
ctgcgctcagacagtgagggcagcgactatactcctggcaagaagaagaagaagaagctt
ggacctaagaaagagaagaagagcaaatccaagcggaaggaggaggaggaggaggaggat
gatgatgatgattcaaaggagcctaaatcatctgctcagctcctggaagactggggcatg
gaagacattgaccacgtgttctcagaggaggattatcgaaccctcaccaactacaaggcc
ttcagccagtttgtcagacccctcattgctgccaaaaatcccaagattgctgtctccaag
atgatgatggttttgggtgcaaaatggcgggagttcagtaccaataaccccttcaaaggc
agttctggggcatcagtggcagctgcggcagcagcagcggtagctgtggtggagagcatg
gtgacagccactgaggttgcaccaccacctccccctgtggaggtgcctatccgcaaggcc
aagaccaaggagggcaaaggtcccaatgctcggaggaagcccaagggcagccctcgtgta
cctgatgccaagaagcctaaacccaagaaagtagctcccctgaaaatcaagctgggaggt
tttggttccaagcgtaagagatcctcgagtgaggatgatgacttagatgtggaatctgac
ttcgatgatgccagtatcaatagctattctgtttctgatggttccaccagccgtagtagc
cgcagccgcaagaaactccgaaccactaaaaagaaaaagaaaggcgaggaggaggtgact
gctgtggatggttatgagacagaccaccaggactattgcgaggtgtgccagcaaggcggt
gagatcatcctgtgtgatacctgtccccgtgcttaccacatggtctgcctggatcccgac
atggagaaggctcccgagggcaagtggagctgcccacactgcgagaaggaaggcatccag
tgggaagctaaagaggacaattcggagggtgaggagatcctggaagaggttgggggagac
ctcgaagaggaggatgaccaccatatggaattctgtcgggtctgcaaggatggtggggaa
ctgctctgctgtgatacctgtccttcttcctaccacatccactgcctgaatcccccactt
ccagagatccccaacggtgaatggctctgtccccgttgtacgtgtccagctctgaagggc
aaagtgcagaagatcctaatctggaagtggggtcagccaccatctcccacaccagtgcct
cggcctccagatgctgatcccaacacgccctccccaaagcccttggaggggcggccagag
cggcagttctttgtgaaatggcaaggcatgtcttactggcactgctcctgggtttctgaa
ctgcagctggagctgcactgtcaggtgatgttccgaaactatcagcggaagaatgatatg
gatgagccaccttctggggactttggtggtgatgaagagaaaagccgaaagcgaaagaac
aaggaccctaaatttgcagagatggaggaacgcttctatcgctatgggataaaacccgag
tggatgatgatccaccgaatcctcaaccacagtgtggacaagaagggccacgtccactac
ttgatcaagtggcgggacttaccttacgatcaggcttcttgggagagtgaggatgtggag
atccaggattacgacctgttcaagcagagctattggaatcacagggagttaatgaggggt
gaggaaggccgaccaggcaagaagctcaagaaggtgaagcttcggaagttggagaggcct
ccagaaacgccaacagttgatccaacagtgaagtatgagcgacagccagagtacctggat
gctacaggtggaaccctgcacccctatcaaatggagggcctgaattggttgcgcttctcc
tgggctcagggcactgacaccatcttggctgatgagatgggccttgggaaaactgtacag
acagcagtcttcctgtattccctttacaaggagggtcattccaaaggccccttcctagtg
agcgcccctctttctaccatcatcaactgggagcgggagtttgaaatgtgggctccagac
atgtatgtcgtaacctatgtgggtgacaaggacagccgtgccatcatccgagagaatgag
ttctcctttgaagacaatgccattcgtggtggcaagaaggcctcccgcatgaagaaagag
gcatctgtgaaattccatgtgctgctgacatcctatgaattgatcaccattgacatggct
attttgggctctattgattgggcctgcctcatcgtggatgaagcccatcggctgaagaac
aatcagtctaagttcttccgggtattgaatggttactcactccagcacaagctgttgctg
actgggacaccattacaaaacaatctggaagagttgtttcatctgctcaactttctcacc
cccgagaggttccacaatttggaaggttttttggaggagtttgctgacattgccaaggag
gaccagataaaaaaactgcatgacatgctggggccgcacatgttgcggcggctcaaagcc
gatgtgttcaagaacatgccctccaagacagaactaattgtgcgtgtggagctgagccct
atgcagaagaaatactacaagtacatcctcactcgaaattttgaagcactcaatgcccga
ggtggtggcaaccaggtgtctctgctgaatgtggtgatggatcttaagaagtgctgcaac
catccatacctcttccctgtggctgcaatggaagctcctaagatgcctaatggcatgtat
gatggcagtgccctaatcagagcatctgggaaattattgctgctgcagaaaatgctcaag
aaccttaaggagggtgggcatcgtgtactcatcttttcccagatgaccaagatgctagac
ctgctagaggatttcttggaacatgaaggttataaatacgaacgcatcgatggtggaatc
actgggaacatgcggcaagaggccattgaccgcttcaatgcaccgggtgctcagcagttc
tgcttcttgctttccactcgagctgggggccttggaatcaatctggccactgctgacaca
gttattatctatgactctgactggaacccccataatgacattcaggcctttagcagagct
caccggattgggcaaaataaaaaggtaatgatctaccggtttgtgacccgtgcgtcagtg
gaggagcgcatcacgcaggtggcaaagaagaaaatgatgctgacgcatctagtggtgcgg
cctgggctgggctccaagactggatctatgtccaaacaggagcttgatgatatcctcaaa
tttggcactgaggaactattcaaggatgaagccactgatggaggaggagacaacaaagag
ggagaagatagcagtgttatccactacgatgataaggccattgaacggctgctagaccgt
aaccaggatgagactgaagacacagaattgcagggcatgaatgaatatttgagctcattc
aaagtggcccagtatgtggtacgggaagaagaaatgggggaggaagaggaggtagaacgg
gaaatcattaaacaggaagaaagtgtggatcctgactactgggagaaattgctgcggcac
cattatgagcagcagcaagaagatctagcccgaaatctgggcaaaggaaaaagaatccgt
aaacaggtcaactacaatgatggctcccaggaggaccgagattggcaggacgaccagtcc
gacaaccagtccgattactcagtggcttcagaggaaggtgatgaagactttgatgaacgt
tcagaagctccccgtaggcccagtcgtaagggcctgcggaatgataaagataagccattg
cctcctctgttggcccgtgttggtgggaatattgaagtacttggttttaatgctcgtcag
cgaaaagcctttcttaatgcaattatgcgatatggtatgccacctcaggatgcttttact
acccagtggcttgtaagagacctgcgaggcaaatcagagaaagagttcaaggcatatgtc
tctcttttcatgcggcatttatgtgagccgggggcagatggggctgagacctttgctgat
ggtgtcccccgagaaggcctgtctcgccagcatgtccttactagaattggtgttatgtct
ttgattcgcaagaaggttcaggagtttgaacatgttaatgggcgctggagcatgcctgaa
ctggctgaggtggaggaaaacaagaagatgtcccagccagggtcaccctccccaaaaact
cctacaccctccactccaggggacacgcagcccaacactcctgcacctgtcccacctgct
gaagatgggataaaaatagaggaaaatagcctcaaagaagaagagagcatagaaggagaa
aaggaggttaaatctacagcccctgagactgccattgagtgtacacaggcccctgcccct
gcctcagaggatgaaaaggtcgttgttgaaccccctgagggagaggagaaagtggaaaag
gcagaggtgaaggagagaacagaggaacctatggagacagagcccaaaggtgctgctgat
gtagagaaggtggaggaaaagtcagcaatagatctgacccctattgtggtagaagacaaa
gaagagaagaaagaagaagaagagaaaaaagaggtgatgcttcagaatggagagaccccc
aaggacctgaatgatgagaaacagaagaaaaatattaaacaacgtttcatgtttaacatt
gcagatggtggttttactgagttgcactccctttggcagaatgaagagcgggcagccaca
gttaccaagaagacttatgagatctggcatcgacggcatgactactggctgctagccggc
attataaaccatggctatgcccggtggcaagacatccagaatgacccacgctatgccatc
ctcaatgagcctttcaagggtgaaatgaaccgtggcaatttcttagagatcaagaataaa
tttctagctcgaaggtttaagctcttagaacaagctctggtgattgaggaacagctgcgc
cgggctgcttacttgaacatgtcagaagacccttctcacccttccatggccctcaacacc
cgctttgctgaggtggagtgtttggcggaaagtcatcagcacctgtccaaggagtcaatg
gcaggaaacaagccagccaatgcagtcctgcacaaagttctgaaacagctggaagaactg
ctgagtgacatgaaagctgatgtgactcgactcccagctaccattgcccgaattccccca
gttgctgtgaggttacagatgtcagagcgtaacattctcagccgcctggcaaaccgggca
cccgaacctaccccacagcaggtagcccagcagcagtga
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integrated database retrieval system