Homo sapiens (human): 11096
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Entry
11096 CDS
T01001
Symbol
ADAMTS5, ADAM-TS_11, ADAM-TS_5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2
Name
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 5
KO
K08620
a disintegrin and metalloproteinase with thrombospondin motifs 5 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Drug target
Aldumastat:
D11995
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
11096 (ADAMTS5)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
11096 (ADAMTS5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ADAMTS_spacer1
Reprolysin
ADAMTS_CR_2
Reprolysin_5
Reprolysin_3
TSP1_ADAMTS
ADAMTS_CR_3
TSP_1
Reprolysin_2
Reprolysin_4
TSP1_spondin
Peptidase_M10
Pep_M12B_propep
TSP1_CCN
DUF4953
Toprim_Crpt
CxC6
Motif
Other DBs
NCBI-GeneID:
11096
NCBI-ProteinID:
NP_008969
OMIM:
605007
HGNC:
221
Ensembl:
ENSG00000154736
UniProt:
Q9UNA0
Structure
PDB
PDBj
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All DBs
Position
21:complement(26917922..26967088)
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AA seq
930 aa
AA seq
DB search
MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGH
PHPLAQRRRSKGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGT
SAPWRHRSHCFYRGTVDGSPRSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGR
VYGDGSARILHVYTREGFSFEALPPRASCETPASTPEAHEHAPAHSNPSGRAALASQLLD
QSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRGLQHYLLTLASIANR
LYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQLGDDHEEHYD
AAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSH
DDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQI
LGPEELPGQTYDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGT
PCGKGRICLQGKCVDKTKKKYYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPR
NNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNGYQSDAKGVKTFVEWVPKYAGVL
PADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVCVRGKCVRTGCDGIIGSKLQYDK
CGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTRFTAYLALKKK
NGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPT
KPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTV
QCQDGNRKLAKGCPLSQRPSAFKQCLLKKC
NT seq
2793 nt
NT seq
+upstream
nt +downstream
nt
atgctgctcgggtgggcgtccctgctgctgtgcgcgttccgcctgcccctggccgcggtc
ggccccgccgcgacacctgcccaggataaagccgggcagcctccgactgctgcagcagcc
gcccagccccgccggcggcagggggaggaggtgcaggagcgagccgagcctcccggccac
ccgcaccccctggcgcagcggcgcaggagcaaggggctggtgcagaacatcgaccaactc
tactccggcggcggcaaggtgggctacctcgtctacgcgggcggccggaggttcctcttg
gacctggagcgagatggttcggtgggcattgctggcttcgtgcccgcaggaggcgggacg
agtgcgccctggcgccaccggagccactgcttctatcggggcacagtggacggtagtccc
cgctctctggctgtctttgacctctgtgggggtctcgacggcttcttcgcggtcaagcac
gcgcgctacaccctaaagccactgctgcgcggaccctgggcggaggaagaaaaggggcgc
gtgtacggggatgggtccgcacggatcctgcacgtctacacccgcgagggcttcagcttc
gaggccctgccgccgcgcgccagctgcgaaacccccgcgtccacaccggaggcccacgag
catgctccggcgcacagcaacccgagcggacgcgcagcactggcctcgcagctcttggac
cagtccgctctctcgcccgctgggggctcaggaccgcagacgtggtggcggcggcggcgc
cgctccatctcccgggcccgccaggtggagctgcttctggtggctgacgcgtccatggcg
cggttgtatggccggggcctgcagcattacctgctgaccctggcctccatcgccaatagg
ctgtacagccatgctagcatcgagaaccacatccgcctggccgtggtgaaggtggtggtg
ctaggcgacaaggacaagagcctggaagtgagcaagaacgctgccaccacactcaagaac
ttttgcaagtggcagcaccaacacaaccagctgggagatgaccatgaggagcactacgat
gcagctatcctgtttactcgggaggatttatgtgggcatcattcatgtgacaccctggga
atggcagacgttgggaccatatgttctccagagcgcagctgtgctgtgattgaagacgat
ggcctccacgcagccttcactgtggctcacgaaatcggacatttacttggcctctcccat
gacgattccaaattctgtgaagagacctttggttccacagaagataagcgcttaatgtct
tccatccttaccagcattgatgcatctaagccctggtccaaatgcacttcagccaccatc
acagaattcctggatgatggccatggtaactgtttgctggacctaccacgaaagcagatc
ctgggccccgaagaactcccaggacagacctacgatgccacccagcagtgcaacctgaca
ttcgggcctgagtactccgtgtgtcccggcatggatgtctgtgctcgcctgtggtgtgct
gtggtacgccagggccagatggtctgtctgaccaagaagctgcctgcggtggaagggacg
ccttgtggaaaggggagaatctgcctgcagggcaaatgtgtggacaaaaccaagaaaaaa
tattattcaacgtcaagccatggcaactggggatcttggggatcctggggccagtgttct
cgctcatgtggaggaggagtgcagtttgcctatcgtcactgtaataaccctgctcccaga
aacaacggacgctactgcacagggaagagggccatctaccgctcctgcagtctcatgccc
tgcccacccaatggtaaatcatttcgtcatgaacagtgtgaggccaaaaatggctatcag
tctgatgcaaaaggagtcaaaacttttgtggaatgggttcccaaatatgcaggtgtcctg
ccagcggatgtgtgcaagctgacctgcagagccaagggcactggctactatgtggtattt
tctccaaaggtgaccgatggcactgaatgtaggctgtacagtaattccgtctgcgtccgg
gggaagtgtgtgagaactggctgtgacggcatcattggctcaaagctgcagtatgacaag
tgcggagtatgtggaggagacaactccagctgtacaaagattgttggaacctttaataag
aaaagtaagggttacactgacgtggtgaggattcctgaaggggcaacccacataaaagtt
cgacagttcaaagccaaagaccagactagattcactgcctatttagccctgaaaaagaaa
aacggtgagtaccttatcaatggaaagtacatgatctccacttcagagactatcattgac
atcaatggaacagtcatgaactatagcggttggagccacagggatgacttcctgcatggc
atgggctactctgccacgaaggaaattctaatagtgcagattcttgcaacagaccccact
aaaccattagatgtccgttatagcttttttgttcccaagaagtccactccaaaagtaaac
tctgtcactagtcatggcagcaataaagtgggatcacacacttcgcagccgcagtgggtc
acgggcccatggctcgcctgctctaggacctgtgacacaggttggcacaccagaacggtg
cagtgccaggatggaaaccggaagttagcaaaaggatgtcctctctcccaaaggccttct
gcgtttaagcaatgcttgttgaagaaatgttag
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