Homo sapiens (human): 11112
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Entry
11112 CDS
T01001
Symbol
HIBADH, NS5ATP1
Name
(RefSeq) 3-hydroxyisobutyrate dehydrogenase
KO
K00020
3-hydroxyisobutyrate dehydrogenase [EC:
1.1.1.31
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00280
Valine, leucine and isoleucine degradation
hsa01100
Metabolic pathways
Network
nt06024
Valine, leucine and isoleucine degradation
Element
N00852
Valine degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
11112 (HIBADH)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.31 3-hydroxyisobutyrate dehydrogenase
11112 (HIBADH)
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GFIT
Motif
Pfam:
NAD_binding_2
NAD_binding_11
2-Hacid_dh_C
F420_oxidored
3HCDH_N
IlvN
TrkA_N
AnkX_ins
RS_preATP-grasp-like
Motif
Other DBs
NCBI-GeneID:
11112
NCBI-ProteinID:
NP_689953
OMIM:
608475
HGNC:
4907
Ensembl:
ENSG00000106049
UniProt:
P31937
A0A024RA75
Structure
PDB
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All DBs
Position
7:complement(27525442..27662883)
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AA seq
336 aa
AA seq
DB search
MAASLRLLGAASGLRYWSRRLRPAAGSFAAVCSRSVASKTPVGFIGLGNMGNPMAKNLMK
HGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAYSGANGIL
KKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLTFMVGGVED
EFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLL
AKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPI
LLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREEETF
NT seq
1011 nt
NT seq
+upstream
nt +downstream
nt
atggcagcctccttacggctcctcggagctgcctccggtctccggtactggagccggcgg
ctgcggccggcagccggcagctttgcagcggtgtgttctaggtcagtggcttcaaagact
ccagttggattcattggactgggcaacatggggaatccaatggcaaaaaatctcatgaaa
catggctatccacttattatttatgatgtgttccctgatgcctgcaaagagtttcaagat
gcaggtgaacaggtagtatcttccccagcagatgttgctgaaaaagctgacagaattatt
acaatgctgcccaccagtatcaatgcaatagaagcttattccggagcaaatgggattcta
aaaaaagtgaagaagggctcattattaatagattccagcactattgatcctgcagtttca
aaagaattggccaaagaagttgagaaaatgggagcagttttcatggatgcccctgtttct
ggtggtgtaggagctgcacgatctgggaacctcacgtttatggtgggaggagttgaagat
gaatttgctgctgcccaagagttgctggggtgcatgggctccaacgtggtgtactgtgga
gctgttgggactgggcaggcggcaaagatctgcaacaacatgctgttagctattagtatg
attggaactgctgaagctatgaatcttggaatcaggttagggcttgacccaaaactactg
gctaaaatcctaaatatgagctcaggacggtgttggtcaagtgacacttataatcctgta
cctggagtgatggatggcgttccctcggctaataactatcagggtggatttggaacaaca
ctcatggctaaggatctgggattggcacaagactctgctaccagcacaaagagcccaatc
cttcttggcagtctggcccatcagatctacaggatgatgtgtgcaaagggctactcaaag
aaagacttctcatccgtgttccagttcctacgagaggaggagaccttctga
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