Homo sapiens (human): 11181
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Entry
11181 CDS
T01001
Symbol
TREH, TRE, TREA, TREHD
Name
(RefSeq) trehalase
KO
K01194
alpha,alpha-trehalase [EC:
3.2.1.28
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00500
Starch and sucrose metabolism
hsa01100
Metabolic pathways
Disease
H02090
Trehalase deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00500 Starch and sucrose metabolism
11181 (TREH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
11181 (TREH)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.28 alpha,alpha-trehalase
11181 (TREH)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
Enzymes
11181 (TREH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Trehalase
Glyco_hydro_63
Motif
Other DBs
NCBI-GeneID:
11181
NCBI-ProteinID:
NP_009111
OMIM:
275360
HGNC:
12266
Ensembl:
ENSG00000118094
UniProt:
O43280
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Position
11:complement(118657316..118679650)
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AA seq
583 aa
AA seq
DB search
MPGRTWELCLLLLLGLGLGSQEALPPPCESEIYCHGELLNQVQMAKLYQDDKQFVDMPLS
IAPEQVLQTFTELSRDHNHSIPREQLQAFVHEHFQAKGQELQPWTPADWKDSPQFLQKIS
DAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEHPFIVPGGRFVEFYYWDSYWV
MEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTND
TAFLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVPYGGPRPESYSKDVELADTL
PEGDREALWAELKAGAESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELM
SNFYSRLGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTP
LWAGCFSDPGVADKALKYLEDNRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLA
KAPLRRAQEVAFQLAQNWIRTNFDVYSQKSAMYEKYDVSNGGQPGGGGEYEVQEGFGWTN
GVVLMLLDRYGDRLTSGAKLAFLEPHCLAATLLPSLLLSLLPW
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgccagggaggacctgggagctgtgcctgctactgctgctggggctgggactggggtcc
caggaggccctacccccaccctgtgagagtgagatttactgccacggggagctcctaaac
caagttcaaatggccaagctctaccaggatgacaagcagtttgtggacatgccactgtct
atagctccagaacaagtcctgcagaccttcactgagctgtccagggaccacaatcacagc
atccccagggagcagctgcaggcgtttgtccacgaacacttccaggccaaggggcaggag
ctgcagccctggacccctgcagactggaaagacagcccccagttcctgcagaagatttca
gatgccaaactgcgtgcctgggcagggcagctgcatcagctctggaagaagctggggaag
aagatgaagccagaggttctcagccaccctgagcggttctctctcatctactcagaacat
cccttcattgtgcctggcggtcgctttgttgagttctactactgggactcctactgggtc
atggagggtctgctcctctcagagatggctgagacggtgaagggcatgctgcagaacttc
ttggacctggtgaaaacctatgggcatgtccccaatggtgggcgcgtgtactacctgcag
cggagccagcccccactcttgaccctcatgatggattgctacttgactcacaccaatgac
accgcctttctacaggaaaacattgaaacactagccttggaattggacttttggaccaag
aacaggactgtctctgtgagcttggagggaaagaactacctcctgaatcgctattatgtc
ccttatgggggacccaggcctgagtcctacagcaaagatgtggagttggctgacaccttg
ccagaaggagaccgggaggctctgtgggctgagctcaaggctggggctgagtctggctgg
gacttctcttcacgctggctcattggaggcccaaaccccaactcgcttagcggcatccga
acaagcaaactggtgcctgttgacctgaatgccttcctatgccaagcagaggagctgatg
agcaacttctattccaggctggggaacgactcccaggccacgaagtacagaatcctgcgg
tcgcagcgcttggccgccctgaacacagtcctgtgggatgagcagaccggagcctggttc
gattacgaccttgagaagaagaagaaaaaccgggagttttacccatccaacctcactcca
ctctgggccgggtgtttctctgaccctggcgtggcggacaaggctctgaaatacctggag
gacaaccggatcctgacttaccagtatgggatcccgacctctctccagaagacaggccag
cagtgggatttccccaatgcctgggcccccctgcaggacctggtcatcagaggcctggcc
aaggcacctttacgtcgggcccaggaagtggctttccagctggctcagaattggatccga
accaattttgatgtctactcgcagaagtcagccatgtatgagaagtatgacgtcagcaac
ggtggacagcccggtgggggaggagaatatgaagttcaggagggatttggctggacgaat
ggcgtggtcctgatgctgctggaccgctatggtgaccggctgacctcaggggccaagctg
gctttcctggagccccactgcctggcggccacccttctgcccagcctcctgctcagcctc
ctgccatggtga
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