Homo sapiens (human): 1119 Help Entry 1119              CDS       T01001                                  Symbol CHKA, CHK, CK, CKI, EK, NEDMIMS Name (RefSeq) choline kinase alpha   KO K14156   choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa01100   Metabolic pathways hsa05231   Choline metabolism in cancer Module hsa_M00090   Phosphatidylcholine (PC) biosynthesis, choline => PC hsa_M00092   Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE Disease H02461   Neurodevelopmental disorder with microcephaly Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     1119 (CHKA)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     1119 (CHKA) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.32  choline kinase      1119 (CHKA)     2.7.1.82  ethanolamine kinase      1119 (CHKA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Choline_kinase APH EcKL Kdo Pkinase_fungal Motif Other DBs NCBI-GeneID:  1119 NCBI-ProteinID:  NP_001268 OMIM:  118491 HGNC:  1937 Ensembl:  ENSG00000110721 UniProt:  P35790 Structure PDBPDBj LinkDB All DBs Position 11:complement(68052859..68121388) Genome browser AA seq 457 aa AA seqDB search MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPP PPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGL SNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLE SVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKM PFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPV VFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYP FFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLW GLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV NT seq 1374 nt NT seq  +upstreamnt  +downstreamnt atgaaaaccaaattctgcaccgggggcgaggcggagccctcgccgctcgggctgctgctg agctgcggtagcggcagcgcggccccggcgcccggcgtggggcagcagcgcgacgccgcc agcgacctcgagtccaagcagctgggcggccaacagccgccgctcgcgctgccccctccg ccgccgctgccgctgccgctgccgctgccccagcccccgccgccgcagccgcccgcagac gagcagccggagccccggacgcggcgcagggcctatctgtggtgcaaggagttcctgccc ggcgcctggcggggcctccgcgaggacgagttccacatcagtgtcatcagaggcggcctt agcaacatgctgttccagtgctccctacctgacaccacagccacccttggtgatgagcct cggaaagtgctcctgcggctgtatggagcgattttgcagatgaggtcctgtaataaagag ggatccgaacaagctcagaaagaaaatgaatttcaaggggctgaggccatggttctggag agcgttatgtttgccattctcgcagagaggtcacttgggccaaaactctatggcatcttt ccccaaggccgactggagcagttcatcccgagccggcgattagatactgaagaattaagt ttgccagatatttctgcagaaatcgccgagaaaatggctacatttcatggtatgaaaatg ccattcaataaggaaccaaaatggctttttggcacaatggaaaagtatctaaaggaagtg ctgagaattaaatttactgaggaatccagaattaaaaagctccacaaattgctcagttac aatctgcccttggaactggaaaacctgagatcattgcttgaatctactccatctccagtt gtattttgtcataatgactgtcaagaaggtaatatcttgttgctggaaggccgagagaat tctgaaaaacagaaactgatgctcattgatttcgaatacagcagttacaattacagggga ttcgacattggaaatcacttctgtgagtggatgtatgattatagctatgaaaaataccct tttttcagagcaaacatccggaagtatcccaccaagaaacaacagctccattttatttcc agttacttgcctgcattccaaaatgactttgaaaacctcagtactgaagaaaaatccatt ataaaagaagaaatgttgcttgaagttaataggtttgcccttgcatctcatttcctctgg ggactgtggtccattgtacaagccaagatttcatctattgaatttgggtacatggactac gcccaagcaaggtttgatgcctatttccaccagaagaggaagcttggggtgtga

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