Homo sapiens (human): 1179
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Entry
1179 CDS
T01001
Symbol
CLCA1, CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1
Name
(RefSeq) chloride channel accessory 1
KO
K05027
calcium-activated chloride channel regulator 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04924
Renin secretion
hsa04972
Pancreatic secretion
Drug target
Crofelemer:
D03605
<US>
Niflumic acid:
D08275
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
1179 (CLCA1)
09154 Digestive system
04972 Pancreatic secretion
1179 (CLCA1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
1179 (CLCA1)
Ion channels [BR:
hsa04040
]
Chloride channels
Chloride channel, calcium-activated (CaCC)
1179 (CLCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CLCA
VWA_2
VWA
VWA_CoxE
DUF444
Motif
Other DBs
NCBI-GeneID:
1179
NCBI-ProteinID:
NP_001276
OMIM:
603906
HGNC:
2015
Ensembl:
ENSG00000016490
UniProt:
A8K7I4
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:86468927..86500259
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AA seq
914 aa
AA seq
DB search
MGPFKSSVFILILHLLEGALSNSLIQLNNNGYEGIVVAIDPNVPEDETLIQQIKDMVTQA
SLYLLEATGKRFYFKNVAILIPETWKTKADYVRPKLETYKNADVLVAESTPPGNDEPYTE
QMGNCGEKGERIHLTPDFIAGKKLAEYGPQGRAFVHEWAHLRWGVFDEYNNDEKFYLSNG
RIQAVRCSAGITGTNVVKKCQGGSCYTKRCTFNKVTGLYEKGCEFVLQSRQTEKASIMFA
QHVDSIVEFCTEQNHNKEAPNKQNQKCNLRSTWEVIRDSEDFKKTTPMTTQPPNPTFSLL
QIGQRIVCLVLDKSGSMATGNRLNRLNQAGQLFLLQTVELGSWVGMVTFDSAAHVQNELI
QINSGSDRDTLAKRLPAAASGGTSICSGLRSAFTVIRKKYPTDGSEIVLLTDGEDNTISG
CFNEVKQSGAIIHTVALGPSAAQELEELSKMTGGLQTYASDQVQNNGLIDAFGALSSGNG
AVSQRSIQLESKGLTLQNSQWMNGTVIVDSTVGKDTLFLITWTMQPPQILLWDPSGQKQG
GFVVDKNTKMAYLQIPGIAKVGTWKYSLQASSQTLTLTVTSRASNATLPPITVTSKTNKD
TSKFPSPLVVYANIRQGASPILRASVTALIESVNGKTVTLELLDNGAGADATKDDGVYSR
YFTTYDTNGRYSVKVRALGGVNAARRRVIPQQSGALYIPGWIENDEIQWNPPRPEINKDD
VQHKQVCFSRTSSGGSFVASDVPNAPIPDLFPPGQITDLKAEIHGGSLINLTWTAPGDDY
DHGTAHKYIIRISTSILDLRDKFNESLQVNTTALIPKEANSEEVFLFKPENITFENGTDL
FIAIQAVDKVDLKSEISNIARVSLFIPPQTPPETPSPDETSAPCPNIHINSTIPGIHILK
IMWKWIGELQLSIA
NT seq
2745 nt
NT seq
+upstream
nt +downstream
nt
atggggccatttaagagttctgtgttcatcttgattcttcaccttctagaaggggccctg
agtaattcactcattcagctgaacaacaatggctatgaaggcattgtcgttgcaatcgac
cccaatgtgccagaagatgaaacactcattcaacaaataaaggacatggtgacccaggca
tctctgtatctgcttgaagctacaggaaagcgattttatttcaaaaatgttgccattttg
attcctgaaacatggaagacaaaggctgactatgtgagaccaaaacttgagacctacaaa
aatgctgatgttctggttgctgagtctactcctccaggtaatgatgaaccctacactgag
cagatgggcaactgtggagagaagggtgaaaggatccacctcactcctgatttcattgca
ggaaaaaagttagctgaatatggaccacaaggtagggcatttgtccatgagtgggctcat
ctacgatggggagtatttgacgagtacaataatgatgagaaattctacttatccaatgga
agaatacaagcagtaagatgttcagcaggtattactggtacaaatgtagtaaagaagtgt
cagggaggcagctgttacaccaaaagatgcacattcaataaagtaacaggactctatgaa
aaaggatgtgagtttgttctccaatcccgccagacggagaaggcttctataatgtttgca
caacatgttgattctatagttgaattctgtacagaacaaaaccacaacaaagaagctcca
aacaagcaaaatcaaaaatgcaatctccgaagcacatgggaagtgatccgtgattctgag
gactttaagaaaaccactcctatgacaacacagccaccaaatcccaccttctcattgctg
cagattggacaaagaattgtgtgtttagtccttgacaaatctggaagcatggcgactggt
aaccgcctcaatcgactgaatcaagcaggccagcttttcctgctgcagacagttgagctg
gggtcctgggttgggatggtgacatttgacagtgctgcccatgtacaaaatgaactcata
cagataaacagtggcagtgacagggacacactcgccaaaagattacctgcagcagcttca
ggagggacgtccatctgcagcgggcttcgatcggcatttactgtgattaggaagaaatat
ccaactgatggatctgaaattgtgctgctgacggatggggaagacaacactataagtggg
tgctttaacgaggtcaaacaaagtggtgccatcatccacacagtcgctttggggccctct
gcagctcaagaactagaggagctgtccaaaatgacaggaggtttacagacatatgcttca
gatcaagttcagaacaatggcctcattgatgcttttggggccctttcatcaggaaatgga
gctgtctctcagcgctccatccagcttgagagtaagggattaaccctccagaacagccag
tggatgaatggcacagtgatcgtggacagcaccgtgggaaaggacactttgtttcttatc
acctggacaatgcagcctccccaaatccttctctgggatcccagtggacagaagcaaggt
ggctttgtagtggacaaaaacaccaaaatggcctacctccaaatcccaggcattgctaag
gttggcacttggaaatacagtctgcaagcaagctcacaaaccttgaccctgactgtcacg
tcccgtgcgtccaatgctaccctgcctccaattacagtgacttccaaaacgaacaaggac
accagcaaattccccagccctctggtagtttatgcaaatattcgccaaggagcctcccca
attctcagggccagtgtcacagccctgattgaatcagtgaatggaaaaacagttaccttg
gaactactggataatggagcaggtgctgatgctactaaggatgacggtgtctactcaagg
tatttcacaacttatgacacgaatggtagatacagtgtaaaagtgcgggctctgggagga
gttaacgcagccagacggagagtgataccccagcagagtggagcactgtacatacctggc
tggattgagaatgatgaaatacaatggaatccaccaagacctgaaattaataaggatgat
gttcaacacaagcaagtgtgtttcagcagaacatcctcgggaggctcatttgtggcttct
gatgtcccaaatgctcccatacctgatctcttcccacctggccaaatcaccgacctgaag
gcggaaattcacgggggcagtctcattaatctgacttggacagctcctggggatgattat
gaccatggaacagctcacaagtatatcattcgaataagtacaagtattcttgatctcaga
gacaagttcaatgaatctcttcaagtgaatactactgctctcatcccaaaggaagccaac
tctgaggaagtctttttgtttaaaccagaaaacattacttttgaaaatggcacagatctt
ttcattgctattcaggctgttgataaggtcgatctgaaatcagaaatatccaacattgca
cgagtatctttgtttattcctccacagactccgccagagacacctagtcctgatgaaacg
tctgctccttgtcctaatattcatatcaacagcaccattcctggcattcacattttaaaa
attatgtggaagtggataggagaactgcagctgtcaatagcctag
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