Homo sapiens (human): 1191
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Entry
1191 CDS
T01001
Symbol
CLU, AAG4, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2
Name
(RefSeq) clusterin
KO
K17252
clusterin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
Network
nt06513
Complement cascade
Element
N01505
Regulation of complement cascade, MAC inhibition
Drug target
Custirsen sodium:
D09403
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
1191 (CLU)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
hsa03110
]
1191 (CLU)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
1191 (CLU)
Chaperones and folding catalysts [BR:
hsa03110
]
Other chaperones and cochaperones
Others
1191 (CLU)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of hepatic cells
1191 (CLU)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Clusterin
ApoLp-III
SOAR
Peptidase_M26_N
RPW8
CREPT
APG6_N
Motif
Other DBs
NCBI-GeneID:
1191
NCBI-ProteinID:
NP_001822
OMIM:
185430
HGNC:
2095
Ensembl:
ENSG00000120885
UniProt:
P10909
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(27596917..27614700)
Genome browser
AA seq
449 aa
AA seq
DB search
MMKTLLLFVGLLLTWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLI
EKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWEECKPCLKQT
CMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDRIDSLLENDRQQTHMLDVMQDHF
SRASSIIDELFQDRFFTREPQDTYHYLPFSLPHRRPHFFFPKSRIVRSLMPFSPYEPLNF
HAMFQPFLEMIHEAQQAMDIHFHSPAFQHPPTEFIREGDDDRTVCREIRHNSTGCLRMKD
QCDKCREILSVDCSTNNPSQAKLRRELDESLQVAERLTRKYNELLKSYQWKMLNTSSLLE
QLNEQFNWVSRLANLTQGEDQYYLRVTTVASHTSDSDVPSGVTEVVVKLFDSDPITVTVP
VEVSRKNPKFMETVAEKALQEYRKKHREE
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atgatgaagactctgctgctgtttgtggggctgctgctgacctgggagagtgggcaggtc
ctgggggaccagacggtctcagacaatgagctccaggaaatgtccaatcagggaagtaag
tacgtcaataaggaaattcaaaatgctgtcaacggggtgaaacagataaagactctcata
gaaaaaacaaacgaagagcgcaagacactgctcagcaacctagaagaagccaagaagaag
aaagaggatgccctaaatgagaccagggaatcagagacaaagctgaaggagctcccagga
gtgtgcaatgagaccatgatggccctctgggaagagtgtaagccctgcctgaaacagacc
tgcatgaagttctacgcacgcgtctgcagaagtggctcaggcctggttggccgccagctt
gaggagttcctgaaccagagctcgcccttctacttctggatgaatggtgaccgcatcgac
tccctgctggagaacgaccggcagcagacgcacatgctggatgtcatgcaggaccacttc
agccgcgcgtccagcatcatagacgagctcttccaggacaggttcttcacccgggagccc
caggatacctaccactacctgcccttcagcctgccccaccggaggcctcacttcttcttt
cccaagtcccgcatcgtccgcagcttgatgcccttctctccgtacgagcccctgaacttc
cacgccatgttccagcccttccttgagatgatacacgaggctcagcaggccatggacatc
cacttccatagcccggccttccagcacccgccaacagaattcatacgagaaggcgacgat
gaccggactgtgtgccgggagatccgccacaactccacgggctgcctgcggatgaaggac
cagtgtgacaagtgccgggagatcttgtctgtggactgttccaccaacaacccctcccag
gctaagctgcggcgggagctcgacgaatccctccaggtcgctgagaggttgaccaggaaa
tacaacgagctgctaaagtcctaccagtggaagatgctcaacacctcctccttgctggag
cagctgaacgagcagtttaactgggtgtcccggctggcaaacctcacgcaaggcgaagac
cagtactatctgcgggtcaccacggtggcttcccacacttctgactcggacgttccttcc
ggtgtcactgaggtggtcgtgaagctctttgactctgatcccatcactgtgacggtccct
gtagaagtctccaggaagaaccctaaatttatggagaccgtggcggagaaagcgctgcag
gaataccgcaaaaagcaccgggaggagtga
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