Homo sapiens (human): 122618
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Entry
122618 CDS
T01001
Symbol
PLD4, C14orf175
Name
(RefSeq) 5'-3' exonuclease PLD4 isoform 2
KO
K16860
phospholipase D3/4 [EC:
3.1.4.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00564
Glycerophospholipid metabolism
hsa00565
Ether lipid metabolism
hsa01100
Metabolic pathways
Disease
H00080
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
122618 (PLD4)
00565 Ether lipid metabolism
122618 (PLD4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
122618 (PLD4)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.4 phospholipase D
122618 (PLD4)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
122618 (PLD4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLDc_3
PLDc_2
DUF7436
PLDc
Motif
Other DBs
NCBI-GeneID:
122618
NCBI-ProteinID:
NP_620145
OMIM:
618488
HGNC:
23792
Ensembl:
ENSP00000376372.5
UniProt:
Q96BZ4
B4DI07
B4DJQ6
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:104924879..104937785
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AA seq
506 aa
AA seq
DB search
MLKPLWKAAVAPTWPCSMPPRRPWDREAGTLQVLGALAVLWLGSVALICLLWQVPRPPTW
GQVQPKDVPRSWEHGSSPAWEPLEAEARQQRDSCQLVLVESIPQDLPSAAGSPSAQPLGQ
AWLQLLDTAQESVHVASYYWSLTGPDIGVNDSSSQLGEALLQKLQQLLGRNISLAVATSS
PTLARTSTDLQVLAARGAHVRQVPMGRLTRGVLHSKFWVVDGRHIYMGSANMDWRSLTQV
KELGAVIYNCSHLAQDLEKTFQTYWVLGVPKAVLPKTWPQNFSSHFNRFQPFHGLFDGVP
TTAYFSASPPALCPQGRTRDLEALLAVMGSAQEFIYASVMEYFPTTRFSHPPRYWPVLDN
ALRAAAFGKGVRVRLLVGCGLNTDPTMFPYLRSLQALSNPAANVSVDVKVFIVPVGNHSN
IPFSRVNHSKFMVTEKAAYIGTSNWSEDYFSSTAGVGLVVTQSPGAQPAGATVQEQLRQL
FERDWSSRYAVGLDGQAPGQDCVWQG
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atgctgaagcctctttggaaagcagcagtggcccccacatggccatgctccatgccgccc
cgccgcccgtgggacagagaggctggcacgttgcaggtcctgggagcgctggctgtgctg
tggctgggctccgtggctcttatctgcctcctgtggcaagtgccccgtcctcccacctgg
ggccaggtgcagcccaaggacgtgcccaggtcctgggagcatggctccagcccagcttgg
gagcccctggaagcagaggccaggcagcagagggactcctgccagcttgtccttgtggaa
agcatcccccaggacctgccatctgcagccggcagcccctctgcccagcctctgggccag
gcctggctgcagctgctggacactgcccaggagagcgtccacgtggcttcatactactgg
tccctcacagggcctgacatcggggtcaacgactcgtcttcccagctgggagaggctctt
ctgcagaagctgcagcagctgctgggcaggaacatttccctggctgtggccaccagcagc
ccgacactggccaggacatccaccgacctgcaggttctggctgcccgaggtgcccatgta
cgacaggtgcccatggggcggctcaccaggggtgttttgcactccaaattctgggttgtg
gatggacggcacatatacatgggcagtgccaacatggactggcggtctctgacgcaggtg
aaggagcttggcgctgtcatctataactgcagccacctggcccaagacctggagaagacc
ttccagacctactgggtactgggggtgcccaaggctgtcctccccaaaacctggcctcag
aacttctcatctcacttcaaccgtttccagcccttccacggcctctttgatggggtgccc
accactgcctacttctcagcgtcgccaccagcactctgtccccagggccgcacccgggac
ctggaggcgctgctggcggtgatggggagcgcccaggagttcatctatgcctccgtgatg
gagtatttccccaccacgcgcttcagccaccccccgaggtactggccggtgctggacaac
gcgctgcgggcggcagccttcggcaagggcgtgcgcgtgcgcctgctggtcggctgcgga
ctcaacacggaccccaccatgttcccctacctgcggtccctgcaggcgctcagcaacccc
gcggccaacgtctctgtggacgtgaaagtcttcatcgtgccggtggggaaccattccaac
atcccattcagcagggtgaaccacagcaagttcatggtcacggagaaggcagcctacata
ggcacctccaactggtcggaggattacttcagcagcacggcgggggtgggcttggtggtc
acccagagccctggcgcgcagcccgcgggggccacggtgcaggagcagctgcggcagctc
tttgagcgggactggagttcgcgctacgccgtcggcctggacggacaggctccgggccag
gactgcgtttggcagggctga
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