| Entry |
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| Symbol |
ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP
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| Name |
(RefSeq) ATP binding cassette subfamily C member 2
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| KO |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
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| Organism |
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| Pathway |
| hsa04981 | Folate transport and metabolism |
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| Disease |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
1244 (ABCC2)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
1244 (ABCC2)
04981 Folate transport and metabolism
1244 (ABCC2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
1244 (ABCC2)
01523 Antifolate resistance
1244 (ABCC2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:hsa02000]
1244 (ABCC2)
Transporters [BR:hsa02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
1244 (ABCC2)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
10:99782640..99852594
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| AA seq |
1545 aa
MLEKFCNSTFWNSSFLDSPEADLPLCFEQTVLVWIPLGYLWLLAPWQLLHVYKSRTKRSS
TTKLYLAKQVFVGFLLILAAIELALVLTEDSGQATVPAVRYTNPSLYLGTWLLVLLIQYS
RQWCVQKNSWFLSLFWILSILCGTFQFQTLIRTLLQGDNSNLAYSCLFFISYGFQILILI
FSAFSENNESSNNPSSIASFLSSITYSWYDSIILKGYKRPLTLEDVWEVDEEMKTKTLVS
KFETHMKRELQKARRALQRRQEKSSQQNSGARLPGLNKNQSQSQDALVLEDVEKKKKKSG
TKKDVPKSWLMKALFKTFYMVLLKSFLLKLVNDIFTFVSPQLLKLLISFASDRDTYLWIG
YLCAILLFTAALIQSFCLQCYFQLCFKLGVKVRTAIMASVYKKALTLSNLARKEYTVGET
VNLMSVDAQKLMDVTNFMHMLWSSVLQIVLSIFFLWRELGPSVLAGVGVMVLVIPINAIL
STKSKTIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFRDQVQNLRKKELKNLLAFS
QLQCVVIFVFQLTPVLVSVVTFSVYVLVDSNNILDAQKAFTSITLFNILRFPLSMLPMMI
SSMLQASVSTERLEKYLGGDDLDTSAIRHDCNFDKAMQFSEASFTWEHDSEATVRDVNLD
IMAGQLVAVIGPVGSGKSSLISAMLGEMENVHGHITIKGTTAYVPQQSWIQNGTIKDNIL
FGTEFNEKRYQQVLEACALLPDLEMLPGGDLAEIGEKGINLSGGQKQRISLARATYQNLD
IYLLDDPLSAVDAHVGKHIFNKVLGPNGLLKGKTRLLVTHSMHFLPQVDEIVVLGNGTIV
EKGSYSALLAKKGEFAKNLKTFLRHTGPEEEATVHDGSEEEDDDYGLISSVEEIPEDAAS
ITMRRENSFRRTLSRSSRSNGRHLKSLRNSLKTRNVNSLKEDEELVKGQKLIKKEFIETG
KVKFSIYLEYLQAIGLFSIFFIILAFVMNSVAFIGSNLWLSAWTSDSKIFNSTDYPASQR
DMRVGVYGALGLAQGIFVFIAHFWSAFGFVHASNILHKQLLNNILRAPMRFFDTTPTGRI
VNRFAGDISTVDDTLPQSLRSWITCFLGIISTLVMICMATPVFTIIVIPLGIIYVSVQMF
YVSTSRQLRRLDSVTRSPIYSHFSETVSGLPVIRAFEHQQRFLKHNEVRIDTNQKCVFSW
ITSNRWLAIRLELVGNLTVFFSALMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTS
EIETNIVAVERITEYTKVENEAPWVTDKRPPPDWPSKGKIQFNNYQVRYRPELDLVLRGI
TCDIGSMEKIGVVGRTGAGKSSLTNCLFRILEAAGGQIIIDGVDIASIGLHDLREKLTII
PQDPILFSGSLRMNLDPFNNYSDEEIWKALELAHLKSFVASLQLGLSHEVTEAGGNLSIG
QRQLLCLGRALLRKSKILVLDEATAAVDLETDNLIQTTIQNEFAHCTVITIAHRLHTIMD
SDKVMVLDNGKIIECGSPEELLQIPGPFYFMAKEAGIENVNSTKF |
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| NT seq |
4638 nt +upstreamnt +downstreamnt
atgctggagaagttctgcaactctactttttggaattcctcattcctggacagtccggag
gcagacctgccactttgttttgagcaaactgttctggtgtggattcccttgggctaccta
tggctcctggccccctggcagcttctccacgtgtataaatccaggaccaagagatcctct
accaccaaactctatcttgctaagcaggtattcgttggttttcttcttattctagcagcc
atagagctggcccttgtactcacagaagactctggacaagccacagtccctgctgttcga
tataccaatccaagcctctacctaggcacatggctcctggttttgctgatccaatacagc
agacaatggtgtgtacagaaaaactcctggttcctgtccctattctggattctctcgata
ctctgtggcactttccaatttcagactctgatccggacactcttacagggtgacaattct
aatctagcctactcctgcctgttcttcatctcctacggattccagatcctgatcctgatc
ttttcagcattttcagaaaataatgagtcatcaaataatccatcatccatagcttcattc
ctgagtagcattacctacagctggtatgacagcatcattctgaaaggctacaagcgtcct
ctgacactcgaggatgtctgggaagttgatgaagagatgaaaaccaagacattagtgagc
aagtttgaaacgcacatgaagagagagctgcagaaagccaggcgggcactccagagacgg
caggagaagagctcccagcagaactctggagccaggctgcctggcttgaacaagaatcag
agtcaaagccaagatgcccttgtcctggaagatgttgaaaagaaaaaaaagaagtctggg
accaaaaaagatgttccaaaatcctggttgatgaaggctctgttcaaaactttctacatg
gtgctcctgaaatcattcctactgaagctagtgaatgacatcttcacgtttgtgagtcct
cagctgctgaaattgctgatctcctttgcaagtgaccgtgacacatatttgtggattgga
tatctctgtgcaatcctcttattcactgcggctctcattcagtctttctgccttcagtgt
tatttccaactgtgcttcaagctgggtgtaaaagtacggacagctatcatggcttctgta
tataagaaggcattgaccctatccaacttggccaggaaggagtacaccgttggagaaaca
gtgaacctgatgtctgtggatgcccagaagctcatggatgtgaccaacttcatgcacatg
ctgtggtcaagtgttctacagattgtcttatctatcttcttcctatggagagagttggga
ccctcagtcttagcaggtgttggggtgatggtgcttgtaatcccaattaatgcgatactg
tccaccaagagtaagaccattcaggtcaaaaatatgaagaataaagacaaacgtttaaag
atcatgaatgagattcttagtggaatcaagatcctgaaatattttgcctgggaaccttca
ttcagagaccaagtacaaaacctccggaagaaagagctcaagaacctgctggcctttagt
caactacagtgtgtagtaatattcgtcttccagttaactccagtcctggtatctgtggtc
acattttctgtttatgtcctggtggatagcaacaatattttggatgcacaaaaggccttc
acctccattaccctcttcaatatcctgcgctttcccctgagcatgcttcccatgatgatc
tcctccatgctccaggccagtgtttccacagagcggctagagaagtacttgggaggggat
gacttggacacatctgccattcgacatgactgcaattttgacaaagccatgcagttttct
gaggcctcctttacctgggaacatgattcggaagccacagtccgagatgtgaacctggac
attatggcaggccaacttgtggctgtgataggccctgtcggctctgggaaatcctccttg
atatcagccatgctgggagaaatggaaaatgtccacgggcacatcaccatcaagggcacc
actgcctatgtcccacagcagtcctggattcagaatggcaccataaaggacaacatcctt
tttggaacagagtttaatgaaaagaggtaccagcaagtactggaggcctgtgctctcctc
ccagacttggaaatgctgcctggaggagatttggctgagattggagagaagggtataaat
cttagtgggggtcagaagcagcggatcagcctggccagagctacctaccaaaatttagac
atctatcttctagatgaccccctgtctgcagtggatgctcatgtaggaaaacatattttt
aataaggtcttgggccccaatggcctgttgaaaggcaagactcgactcttggttacacat
agcatgcactttcttcctcaagtggatgagattgtagttctggggaatggaacaattgta
gagaaaggatcctacagtgctctcctggccaaaaaaggagagtttgctaagaatctgaag
acatttctaagacatacaggccctgaagaggaagccacagtccatgatggcagtgaagaa
gaagacgatgactatgggctgatatccagtgtggaagagatccccgaagatgcagcctcc
ataaccatgagaagagagaacagctttcgtcgaacacttagccgcagttctaggtccaat
ggcaggcatctgaagtccctgagaaactccttgaaaactcggaatgtgaatagcctgaag
gaagacgaagaactagtgaaaggacaaaaactaattaagaaggaattcatagaaactgga
aaggtgaagttctccatctacctggagtacctacaagcaataggattgttttcgatattc
ttcatcatccttgcgtttgtgatgaattctgtggcttttattggatccaacctctggctc
agtgcttggaccagtgactctaaaatcttcaatagcaccgactatccagcatctcagagg
gacatgagagttggagtctacggagctctgggattagcccaaggtatatttgtgttcata
gcacatttctggagtgcctttggtttcgtccatgcatcaaatatcttgcacaagcaactg
ctgaacaatatccttcgagcacctatgagattttttgacacaacacccacaggccggatt
gtgaacaggtttgccggcgatatttccacagtggatgacaccctgcctcagtccttgcgc
agctggattacatgcttcctggggataatcagcacccttgtcatgatctgcatggccact
cctgtcttcaccatcatcgtcattcctcttggcattatttatgtatctgttcagatgttt
tatgtgtctacctcccgccagctgaggcgtctggactctgtcaccaggtccccaatctac
tctcacttcagcgagaccgtatcaggtttgccagttatccgtgcctttgagcaccagcag
cgatttctgaaacacaatgaggtgaggattgacaccaaccagaaatgtgtcttttcctgg
atcacctccaacaggtggcttgcaattcgcctggagctggttgggaacctgactgtcttc
ttttcagccttgatgatggttatttatagagataccctaagtggggacactgttggcttt
gttctgtccaatgcactcaatatcacacaaaccctgaactggctggtgaggatgacatca
gaaatagagaccaacattgtggctgttgagcgaataactgagtacacaaaagtggaaaat
gaggcaccctgggtgactgataagaggcctccgccagattggcccagcaaaggcaagatc
cagtttaacaactaccaagtgcggtaccgacctgagctggatctggtcctcagagggatc
acttgtgacatcggtagcatggagaagattggtgtggtgggcaggacaggagctggaaag
tcatccctcacaaactgcctcttcagaatcttagaggctgccggtggtcagattatcatt
gatggagtagatattgcttccattgggctccacgacctccgagagaagctgaccatcatc
ccccaggaccccatcctgttctctggaagcctgaggatgaatctcgaccctttcaacaac
tactcagatgaggagatttggaaggccttggagctggctcacctcaagtcttttgtggcc
agcctgcaacttgggttatcccacgaagtgacagaggctggtggcaacctgagcataggc
cagaggcagctgctgtgcctgggcagggctctgcttcggaaatccaagatcctggtcctg
gatgaggccactgctgcggtggatctagagacagacaacctcattcagacgaccatccaa
aacgagttcgcccactgcacagtgatcaccatcgcccacaggctgcacaccatcatggac
agtgacaaggtaatggtcctagacaacgggaagattatagagtgcggcagccctgaagaa
ctgctacaaatccctggacccttttactttatggctaaggaagctggcattgagaatgtg
aacagcacaaaattctag |
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