Homo sapiens (human): 126129
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Entry
126129 CDS
T01001
Symbol
CPT1C, CATL1, CPT_I-C, CPT1-B, CPT1P, CPTI-B, CPTIC, SPG73
Name
(RefSeq) carnitine palmitoyltransferase 1C
KO
K19524
carnitine O-palmitoyltransferase 1, brain isoform [EC:
2.3.1.21
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00071
Fatty acid degradation
hsa01212
Fatty acid metabolism
hsa03320
PPAR signaling pathway
hsa04148
Efferocytosis
hsa04152
AMPK signaling pathway
hsa04714
Thermogenesis
hsa04920
Adipocytokine signaling pathway
hsa04922
Glucagon signaling pathway
hsa04936
Alcoholic liver disease
Network
nt06020
beta-Oxidation in mitochondria
Element
N00765
beta-Oxidation, acyl-CoA synthesis
Disease
H00266
Hereditary spastic paraplegia
Drug target
Oxfenicine:
D05292
Perhexiline (
DG00334
):
D05442
D08340
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00071 Fatty acid degradation
126129 (CPT1C)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
126129 (CPT1C)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
126129 (CPT1C)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
126129 (CPT1C)
09159 Environmental adaptation
04714 Thermogenesis
126129 (CPT1C)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
126129 (CPT1C)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
hsa03029
]
126129 (CPT1C)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.21 carnitine O-palmitoyltransferase
126129 (CPT1C)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
126129 (CPT1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Carn_acyltransf
CPT_N
PaaA2
Motif
Other DBs
NCBI-GeneID:
126129
NCBI-ProteinID:
NP_001186681
OMIM:
608846
HGNC:
18540
Ensembl:
ENSG00000169169
UniProt:
Q8TCG5
B3KU49
Structure
PDB
PDBj
LinkDB
All DBs
Position
19:49690662..49713731
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AA seq
803 aa
AA seq
DB search
MAEAHQAVGFRPSLTSDGAEVELSAPVLQEIYLSGLRSWKRHLSRFWNDFLTGVFPASPL
SWLFLFSAIQLAWFLQLDPSLGLMEKIKELLPDWGGQHHGLRGVLAAALFASCLWGALIF
TLHVALRLLLSYHGWLLEPHGAMSSPTKTWLALVRIFSGRHPMLFSYQRSLPRQPVPSVQ
DTVRKYLESVRPILSDEDFDWTAVLAQEFLRLQASLLQWYLRLKSWWASNYVSDWWEEFV
YLRSRNPLMVNSNYYMMDFLYVTPTPLQAARAGNAVHALLLYRHRLNRQEIPPTLLMGMR
PLCSAQYEKIFNTTRIPGVQKDYIRHLHDSQHVAVFHRGRFFRMGTHSRNSLLSPRALEQ
QFQRILDDPSPACPHEEHLAALTAAPRGTWAQVRTSLKTQAAEALEAVEGAAFFVSLDAE
PAGLTREDPAASLDAYAHALLAGRGHDRWFDKSFTLIVFSNGKLGLSVEHSWADCPISGH
MWEFTLATECFQLGYSTDGHCKGHPDPTLPQPQRLQWDLPDQIHSSISLALRGAKILSEN
VDCHVVPFSLFGKSFIRRCHLSSDSFIQIALQLAHFRDRGQFCLTYESAMTRLFLEGRTE
TVRSCTREACNFVRAMEDKEKTDPQCLALFRVAVDKHQALLKAAMSGQGVDRHLFALYIV
SRFLHLQSPFLTQVHSEQWQLSTSQIPVQQMHLFDVHNYPDYVSSGGGFGPADDHGYGVS
YIFMGDGMITFHISSKKSSTKTDSHRLGQHIEDALLDVASLFQAGQHFKRRFRGSGKENS
RHRCGFLSRQTGASKASMTSTDF
NT seq
2412 nt
NT seq
+upstream
nt +downstream
nt
atggctgaagcgcaccaggccgtgggcttccgaccctcgctgacctcggacggggctgaa
gtggaactcagtgcccctgtgctgcaggagatctacctctctggcctgcgctcctggaaa
aggcatctctcacgtttctggaatgactttctcaccggtgtgtttcctgccagccccctc
agttggcttttcctcttcagtgccatccagcttgcctggttcctccagctggatccttcc
ttaggactgatggagaagatcaaagagttgctgcctgactggggtggacaacaccacggg
ctccggggggtcctggcagccgcgctgtttgcctcgtgtttgtggggagccctgatcttc
acactgcacgtggccctgaggctgcttctgtcctaccacggctggcttcttgagccccac
ggagccatgtcctcccccaccaagacctggctggccctggtccgcatcttctctggccgc
cacccgatgctgttcagttaccagcgctccctgccacgccagcccgtgccctctgtgcag
gacaccgtgcgcaagtacctggagtcggtccggcccatcctctccgacgaggacttcgac
tggaccgcggtcctggcgcaggaattcctgaggctgcaggcgtcgctgctgcagtggtac
ctgcggctcaagtcctggtgggcgtccaattatgtcagtgactggtgggaggaatttgtg
tacctgcgctcccgaaatccgctgatggtgaacagcaactattacatgatggacttcctg
tatgtcacacccacgcctctgcaggcagctcgcgctgggaatgccgtccatgccctcctc
ctgtaccgccaccgcctgaaccgccaggagatacccccgactttgctgatgggaatgcgc
cccttatgctctgcccagtacgagaagatcttcaacaccacgcggattccaggggtccaa
aaagactacatccgccacctccatgacagccaacacgtggctgtcttccaccggggccga
ttcttccgcatggggacccactcccgaaacagcctgctttccccgagagccctggagcag
cagtttcagagaatcctggatgatccctcaccggcctgcccccacgaggaacatctggca
gctctgacagctgctcccaggggcacgtgggcccaggtgcggacatccctgaagacccag
gcagcggaggccctggaggcggtggaaggggccgctttctttgtgtcactggatgctgag
cccgcggggctcaccagggaggacccggcagcgtcgttggatgcctacgcccatgctctg
ctggccggccggggccatgatcgctggtttgacaaatccttcaccctaatcgtcttctct
aacgggaagctgggcctcagcgtggagcactcctgggccgactgccccatctcaggacac
atgtgggagttcactctggctacagaatgctttcagctgggctactcaacagacggccac
tgcaaggggcacccggaccccacactaccccagccccagcggctgcaatgggaccttcca
gaccagatccactcctccatctctctagccctgaggggagccaagatcttgtctgaaaat
gtcgactgccatgtcgttccattctccctatttggcaagagcttcatccgacgctgccac
ctctcttcagacagcttcatccagatcgccttgcaactggcccacttccgggacaggggt
caattctgcctgacttatgagtcggccatgactcgcttattcctggaaggccggacggag
acggtgcggtcttgcacgagggaggcctgcaactttgtcagggccatggaggacaaagag
aagacggacccacagtgcctcgccctgttccgcgtggcagtggacaagcaccaggctctg
ctgaaggcagccatgagcgggcagggagttgaccgccacctgtttgcgctgtacatcgtg
tcccgattcctccacctgcagtcgcccttcctgacccaggtccattcggagcagtggcag
ctgtccaccagccagatccctgttcagcaaatgcatctgtttgacgtccacaattacccg
gactatgtttcctcaggcggtggattcgggcctgctgatgaccatggttatggtgtttct
tatatcttcatgggggatggcatgatcaccttccacatctccagcaaaaaatcaagcaca
aaaacggattcccacaggctggggcagcacattgaggacgcactgctggatgtggcctcc
ctgttccaggcgggacagcattttaagcgccggttcagagggtcagggaaggagaactcc
aggcacaggtgtggatttctctcccgccagactggggcctccaaggcctcaatgacatcc
accgacttctga
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