KEGG T01001: 128

Homo sapiens (human): 128

Entry

128               CDS       T01001

Symbol

ADH5, ADH-3, ADHX, AMEDS, BMFS7, FALDH, FDH, GSH-FDH, GSNOR, HEL-S-60p

Name

(RefSeq) alcohol dehydrogenase 5 (class III), chi polypeptide

K00121

S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]

Organism

hsa Homo sapiens (human)

Pathway

hsa00010

Glycolysis / Gluconeogenesis

hsa00071

Fatty acid degradation

hsa00350

Tyrosine metabolism

hsa00620

Pyruvate metabolism

hsa00830

Retinol metabolism

hsa00980

Metabolism of xenobiotics by cytochrome P450

hsa00982

Drug metabolism - cytochrome P450

hsa01100

Metabolic pathways

hsa01200

Carbon metabolism

hsa04936

Alcoholic liver disease

Disease

H02529

Bone marrow failure syndrome

Brite

KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    128 (ADH5)
   00620 Pyruvate metabolism
    128 (ADH5)
  09103 Lipid metabolism
   00071 Fatty acid degradation
    128 (ADH5)
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    128 (ADH5)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    128 (ADH5)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    128 (ADH5)
   00982 Drug metabolism - cytochrome P450
    128 (ADH5)
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    128 (ADH5)
Enzymes [BR:hsa01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.1  alcohol dehydrogenase
     128 (ADH5)
    1.1.1.284  S-(hydroxymethyl)glutathione dehydrogenase
     128 (ADH5)

SSDB

Motif

Pfam:

ADH_zinc_N ADH_N Glu_dehyd_C ADH_zinc_N_2

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

4:complement(99070978..99088788)

AA seq 374 aa
MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGC
FPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGK
GLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGY
GAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATEC
INPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEE
IATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFE
LMHSGKSIRTVVKI

NT seq 1125 nt +upstreamnt +downstreamnt
atggcgaacgaggttatcaagtgcaaggctgcagttgcttgggaggctggaaagcctctc
tccatagaggagatagaggtggcacccccaaaggctcatgaagttcgaatcaagatcatt
gccactgcggtttgccacaccgatgcctataccctgagtggagctgatcctgagggttgt
tttccagtgatcttgggacatgaaggtgctggaattgtggaaagtgttggtgagggagtt
actaagctgaaggcgggtgacactgtcatcccactttacatcccacagtgtggagaatgc
aaattttgtctaaatcctaaaactaacctttgccagaagataagagtcactcaagggaaa
ggattaatgccagatggtaccagcagatttacttgcaaaggaaagacaattttgcattac
atgggaaccagcacattttctgaatacacagttgtggctgatatctctgttgctaaaata
gatcctttagcacctttggataaagtctgccttctaggttgtggcatttcaaccggttat
ggtgctgctgtgaacactgccaagttggagcctggctctgtttgtgccgtctttggtctg
ggaggagtcggattggcagttatcatgggctgtaaagtggctggtgcttcccggatcatt
ggtgtggacatcaataaagataaatttgcaagggccaaagagtttggagccactgaatgt
attaaccctcaggattttagtaaacccatccaggaagtgctcattgagatgaccgatgga
ggagtggactattcctttgaatgtattggtaatgtgaaggtcatgagagcagcacttgag
gcatgtcacaagggctggggcgtcagcgtcgtggttggagtagctgcttcaggtgaagaa
attgccactcgtccattccagctggtaacaggtcgcacatggaaaggcactgcctttgga
ggatggaagagtgtagaaagtgtcccaaagttggtgtctgaatatatgtccaaaaagata
aaagttgatgaatttgtgactcacaatctgtcttttgatgaaatcaacaaagcctttgaa
ctgatgcattctggaaagagcattcgaactgttgtaaagatttaa

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