Homo sapiens (human): 131890
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Entry
131890 CDS
T01001
Symbol
GRK7, GPRK7
Name
(RefSeq) G protein-coupled receptor kinase 7
KO
K00909
rhodopsin kinase [EC:
2.7.11.14
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
hsa04144
Endocytosis
hsa04744
Phototransduction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
131890 (GRK7)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
131890 (GRK7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
131890 (GRK7)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.14 rhodopsin kinase
131890 (GRK7)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
131890 (GRK7)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
131890
NCBI-ProteinID:
NP_631948
OMIM:
606987
HGNC:
17031
Ensembl:
ENSG00000114124
UniProt:
Q8WTQ7
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Position
3:141749984..141819352
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AA seq
553 aa
AA seq
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MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC
EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG
NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL
FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK
EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI
ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE
ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT
EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA
KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE
EGNSSKSGVCLLL
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atggtggacatgggggccctggacaacctgatcgccaacaccgcctacctgcaggcccgg
aagccctcggactgcgacagcaaagagctgcagcggcggcggcgtagcctggccctgccc
gggctgcagggctgcgcggagctccgccagaagctgtccctgaacttccacagcctgtgt
gagcagcagcccatcggtcgccgcctcttccgtgacttcctagccacagtgcccacgttc
cgcaaggcggcaaccttcctagaggacgtgcagaactgggagctggccgaggagggaccc
accaaagacagcgcgctgcaggggctggtggccacttgtgcgagtgcccctgccccgggg
aacccgcaacccttcctcagccaggccgtggccaccaagtgccaagcagccaccactgag
gaagagcgagtggctgcagtgacgctggccaaggctgaggccatggctttcttgcaagag
cagccctttaaggatttcgtgaccagcgccttctacgacaagtttctgcagtggaaactc
ttcgagatgcaaccagtgtcagacaagtacttcactgagttcagagtgctggggaaaggt
ggttttggggaggtatgtgccgtccaggtgaaaaacactgggaagatgtatgcctgtaag
aaactggacaagaagcggctgaagaagaaaggtggcgagaagatggctctcttggaaaag
gaaatcttggagaaggtcagcagccctttcattgtctctctggcctatgcctttgagagc
aagacccatctctgccttgtcatgagcctgatgaatgggggagacctcaagttccacatc
tacaacgtgggcacgcgtggcctggacatgagccgggtgatcttttactcggcccagata
gcctgtgggatgctgcacctccatgaactcggcatcgtctatcgggacatgaagcctgag
aatgtgcttctggatgacctcggcaactgcaggttatctgacctggggctggccgtggag
atgaagggtggcaagcccatcacccagagggctggaaccaatggttacatggctcctgag
atcctaatggaaaaggtaagttattcctatcctgtggactggtttgccatgggatgcagc
atttatgaaatggttgctggacgaacaccattcaaagattacaaggaaaaggtcagtaaa
gaggatctgaagcaaagaactctgcaagacgaggtcaaattccagcatgataacttcaca
gaggaagcaaaagatatttgcaggctcttcttggctaagaaaccagagcaacgcttagga
agcagagaaaagtctgatgatcccaggaaacatcatttctttaaaacgatcaactttcct
cgcctggaagctggcctaattgaacccccatttgtgccagacccttcagtggtttatgcc
aaagacatcgctgaaattgatgatttctctgaggttcggggggtggaatttgatgacaaa
gataagcagttcttcaaaaactttgcgacaggtgctgttcctatagcatggcaggaagaa
attatagaaacgggactgtttgaggaactgaatgaccccaacagacctacgggttgtgag
gagggtaattcatccaagtctggcgtgtgtttgttattgtaa
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