| Entry |
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| Symbol |
CPT1B, CPT1-M, CPT1M, CPTI, CPTI-M, M-CPT1, MCCPT1, MCPT1
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| Name |
(RefSeq) carnitine O-palmitoyltransferase 1, muscle isoform isoform a
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| KO |
| K19523 | carnitine O-palmitoyltransferase 1, muscle isoform [EC:2.3.1.21] |
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| Organism |
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| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
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| Network |
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| Element |
| N00765 | beta-Oxidation, acyl-CoA synthesis |
| N01777 | Efferocytosis-induced NAD production |
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| Drug target |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09100 Metabolism
09103 Lipid metabolism
00071 Fatty acid degradation
1375 (CPT1B)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
1375 (CPT1B)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
1375 (CPT1B)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
1375 (CPT1B)
04920 Adipocytokine signaling pathway
1375 (CPT1B)
03320 PPAR signaling pathway
1375 (CPT1B)
09159 Environmental adaptation
04714 Thermogenesis
1375 (CPT1B)
09160 Human Diseases
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
1375 (CPT1B)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
1375 (CPT1B)
04931 Insulin resistance
1375 (CPT1B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:hsa03029]
1375 (CPT1B)
Enzymes [BR:hsa01000]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.21 carnitine O-palmitoyltransferase
1375 (CPT1B)
Mitochondrial biogenesis [BR:hsa03029]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
1375 (CPT1B)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22:complement(50568861..50578612)
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| AA seq |
772 aa
MAEAHQAVAFQFTVTPDGVDFRLSREALKHVYLSGINSWKKRLIRIKNGILRGVYPGSPT
SWLVVIMATVGSSFCNVDISLGLVSCIQRCLPQGCGPYQTPQTRALLSMAIFSTGVWVTG
IFFFRQTLKLLLCYHGWMFEMHGKTSNLTRIWAMCIRLLSSRHPMLYSFQTSLPKLPVPR
VSATIQRYLESVRPLLDDEEYYRMELLAKEFQDKTAPRLQKYLVLKSWWASNYVSDWWEE
YIYLRGRSPLMVNSNYYVMDLVLIKNTDVQAARLGNIIHAMIMYRRKLDREEIKPVMALG
IVPMCSYQMERMFNTTRIPGKDTDVLQHLSDSRHVAVYHKGRFFKLWLYEGARLLKPQDL
EMQFQRILDDPSPPQPGEEKLAALTAGGRVEWAQARQAFFSSGKNKAALEAIERAAFFVA
LDEESYSYDPEDEASLSLYGKALLHGNCYNRWFDKSFTLISFKNGQLGLNAEHAWADAPI
IGHLWEFVLGTDSFHLGYTETGHCLGKPNPALAPPTRLQWDIPKQCQAVIESSYQVAKAL
ADDVELYCFQFLPFGKGLIKKCRTSPDAFVQIALQLAHFRDRGKFCLTYEASMTRMFREG
RTETVRSCTSESTAFVQAMMEGSHTKADLRDLFQKAAKKHQNMYRLAMTGAGIDRHLFCL
YLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGY
GVSYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS |
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| NT seq |
2319 nt +upstreamnt +downstreamnt
atggcggaagctcaccaggccgtggccttccagttcacggtgaccccagacggggtcgac
ttccggctcagtcgggaggccctgaaacacgtctacctgtctgggatcaactcctggaag
aaacgcctgatccgcatcaagaatggcatcctcaggggcgtgtaccctggcagccccacc
agctggctggtcgtcatcatggcaacagtgggttcctccttctgcaacgtggacatctcc
ttggggctggtcagttgcatccagagatgcctccctcaggggtgtggcccctaccagacc
ccgcagacccgggcacttctcagcatggccatcttctccacgggcgtctgggtgacgggc
atcttcttcttccgccaaaccctgaagctgcttctctgctaccatgggtggatgtttgag
atgcatggcaagaccagcaacttgaccaggatctgggctatgtgtatccgccttctatcc
agccggcaccctatgctctacagcttccagacatctctgcccaagcttcctgtgcccagg
gtgtcagccacaattcagcggtacctagagtctgtgcgccccttgttggatgatgaggaa
tattaccgcatggagttgctggccaaagaattccaggacaagactgcccccaggctgcag
aaatacctggtgctcaagtcatggtgggcaagtaactatgtgagtgactggtgggaagag
tacatctaccttcgaggcaggagccctctcatggtgaacagcaactattatgtcatggac
cttgtgctcatcaagaatacagacgtgcaggcagcccgcctgggaaacatcatccacgcc
atgatcatgtatcgccgtaaactggaccgtgaagaaatcaagcctgtgatggcactgggc
atagtgcctatgtgctcctaccagatggagaggatgttcaacaccactcggatcccgggc
aaggacacagatgtgctacagcacctctcagacagccggcacgtggctgtctaccacaag
ggacgcttcttcaagctgtggctctatgagggcgcccgtctgctcaagcctcaggatctg
gagatgcagttccagaggatcctggacgacccctccccacctcagcctggggaggagaag
ctggcagccctcactgcaggaggaagggtggagtgggcgcaggcacgccaggccttcttt
agctctggaaagaataaggctgccttggaggccatcgagcgtgccgctttcttcgtggcc
ctggatgaggaatcctactcctatgaccccgaagatgaggccagcctcagcctctatggc
aaggccctgctacatggcaactgctacaacaggtggtttgacaaatccttcactctcatt
tccttcaagaatggccagttgggtctcaatgcagagcatgcgtgggcagatgctcccatc
attgggcacctctgggagtttgtcctgggcacagacagcttccacctgggctacacggag
accgggcactgcctgggcaaaccgaaccctgcgctcgcacctcctacacggctgcagtgg
gacattccaaaacagtgccaggcggtcatcgagagttcctaccaggtggccaaggcgttg
gcagacgacgtggagttgtactgcttccagttcctgccctttggcaaaggcctcatcaag
aagtgccggaccagccctgatgcctttgtgcagatcgcgctgcagctggctcacttccgg
gacaggggtaagttctgcctgacctatgaggcctcaatgaccagaatgttccgggaggga
cggactgagactgtgcgttcctgtaccagcgagtccacagcctttgtgcaggccatgatg
gaggggtcccacacaaaagcagacctgcgagatctcttccagaaggctgctaagaagcac
cagaatatgtaccgcctggccatgaccggggcagggatcgacaggcacctcttctgcctt
tacttggtctccaagtacctaggagtcagctctcctttccttgctgaggtgctctcggaa
ccctggcgtctctccaccagccagatcccccaatcccagatccgcatgttcgacccagag
cagcaccccaatcacctgggcgctggaggtggctttggccctgtagcagatgatggctat
ggagtttcctacatgattgcaggcgagaacacgatcttcttccacatctccagcaagttc
tcaagctcagagacgaacgcccagcgctttggaaaccacatccgcaaagccctgctggac
attgctgatcttttccaagttcccaaggcctacagctga |
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