KEGG   Homo sapiens (human): 139189
Entry
139189            CDS       T01001                                 
Symbol
DGKK
Name
(RefSeq) diacylglycerol kinase kappa
  KO
K00901  diacylglycerol kinase (ATP) [EC:2.7.1.107]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa04072  Phospholipase D signaling pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    139189 (DGKK)
   00564 Glycerophospholipid metabolism
    139189 (DGKK)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    139189 (DGKK)
   04072 Phospholipase D signaling pathway
    139189 (DGKK)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    139189 (DGKK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.107  diacylglycerol kinase (ATP)
     139189 (DGKK)
SSDB
Motif
Pfam: DAGK_acc DGKD_4H DAGK_cat PH C1_1 Prok-RING_1 PH_3 YegS_C
Other DBs
NCBI-GeneID: 139189
NCBI-ProteinID: NP_001013764
OMIM: 300837
HGNC: 32395
Ensembl: ENSG00000274588
UniProt: Q5KSL6
LinkDB
Position
X:complement(50365409..50470825)
AA seq 1271 aa
MDRGAAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPE
LAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATE
SAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPC
LLQCPVDTRERGLKTSPSPSPSPSPRTPMSWSRIKKILKEGPMLKNCNSFKRWKLRYFLV
QGQKLYFAHHPAFAHFETIDLSQATVAESSCRNLCHSFCVITPQRKITLAAPNRKDMEEW
INIIKTIQQGEIYKIPAAENNPFLVGMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEV
CKVKSHRLCALRASKDCKWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCG
SYQRLQDFRCLWCNSTVHDDCRRRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSDFW
NLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFA
RFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLD
ILNRVEQASVRILDRWSVMIRETPRQTPLLKGQVEMDVPRFEAAAIQHLESAATELNKIL
KAKYPTEMIIATRFLCSAVEDFVVDIVKAWGQIKQNNTAIVSVILKSDLMYDRLSVLIDV
LAEEAAATSAEKSATEYADSSKADRKPFIPQIDHIAKCKLELATKAQSLQKSLKLIIFQV
EQALDEESRQTISVKNFSSTFFLEDDPEDINQTSPRRRSRRGTLSSISSLKSEDLDNLNL
DHLHFTPESIRFKEKCVMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGT
KELLQRSYRKLEERVHLECDGETISLPNLQGIVVLNITSYAGGINFWGSNTATTEYEAPA
IDDGKLEVVAIFGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPG
LIKIRYKNAAQMLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEEYAQMQH
LARLAENLISKLNDLSKIHQHVSVLMGSVNASANILNDIFYGQDSGNEMGAASCIPIETL
SRNDAVDVTFSLKGLYDDTTAFLDEKLLRSAEDETALQSALDAMNKEFKKLSEIDWMNPI
FVPEEKSSDTDSRSLRLKIKFPKLGKKKVEEERKPKSGQSVQSFIGNLWHRRHREDEAEG
DDPLTPSRSQL
NT seq 3816 nt   +upstreamnt  +downstreamnt
atggaccgcggagctgccgcagcccagggcactgccccgcctcaggatggagagcagccc
gctgagtctccagagcctccgccgccttggccgccgccgccaccaccaccggctccgccg
ccggctccgccgctgctctccgaggcttcgccagaacccataccagagccctgtccagag
cttgctccaggtccctgtccagaggcgacctcagaatcagccacagaactgtacacagaa
ccgaccccagaaccagccacagagccggcctcagaaccggccccagaacctgccacagag
ccggccccagaacctgccacagagccggccccagaaccggccccagaacctgccacagag
tctgccccagagccgactccagaacctgccctagagtcggtcccagagccggccccagag
ctgactccagaagttgccccagagctggccccagagccgaccccagaacctgtgacagag
ctggccccagagttctgccctgaggcggctccagagttccgtccaagtccagcaccatgt
ctattgcaatgtccggtggacactcgagagagaggtctaaagacctcgccatcgccatcg
ccatcgccatcgcccagaacgccaatgtcgtggtccagaataaagaaaatattgaaggaa
ggacctatgctgaagaactgtaactctttcaagagatggaagcttagatattttctggtt
caaggacagaagctctactttgcacaccatcccgcgtttgcacactttgaaacgattgat
ctgtctcaagccactgtggcagaaagcagctgtagaaacctttgccacagtttttgtgtt
attacaccacaacgaaaaatcactctggctgcacccaaccggaaagacatggaagaatgg
attaacatcataaaaaccatccaacagggagaaatttataagatacctgcagcagaaaac
aacccttttcttgttggaatgcattgttggtactccagttacagccaccggacccagcac
tgcaatgtttgtcgagagagcattcctgccttatctagagatgccatcatctgtgaagtg
tgcaaagtgaaatctcacagattgtgtgctttgagagcaagcaaagactgcaagtggaat
acattgtctatcactgatgacctccttctgcctgcagatgaagtaaacatgccccatcaa
tgggtagaaggaaacatgcctgtcagctctcagtgtgcagtgtgtcatgagagctgtggc
agttatcaaagacttcaagacttccgctgcctgtggtgtaattctacggtgcatgatgac
tgtaggagacggttttccaaggaatgttgcttcagaagccatcgctcatcagtcattcct
cccactgctctaagcgaccccaaaggcgatggccaattagtagtatcttcagacttctgg
aatcttgattggtcatcagcctgttcatgtcccttgctcatcttcatcaactccaaaagt
ggcgatcatcaggggatcgtcttcctccgaaaattcaagcaataccttaacccatctcaa
gtgttcgacttattgaagggtggacctgaagcagggctgtctatgttcaagaactttgct
cgctttcgcattctggtttgtggtggagatggcagcgtgagctgggtcttatctctgatt
gatgcctttggattacatgaaaagtgtcagttggcagtcatcccacttggaaccggcaat
gatctggctcgtgttctgggctggggtgcattctggaacaaaagcaagtcacctctggac
atcctcaacagagtggagcaggctagtgtgaggatcctagacagatggagtgtgatgatt
cgtgagactcccagacaaaccccgctgctaaaaggacaggttgaaatggatgtaccacga
tttgaggctgctgccatccaacacttagaatctgcagccaccgagttgaacaaaatcctg
aaggccaagtaccccacagagatgatcatcgcaaccagattcttgtgttcagctgtggaa
gattttgtggttgatattgtaaaggcctggggtcagataaaacagaacaacactgcaata
gtgtctgtgattttgaaaagtgacttaatgtatgataggctcagtgtcctgatcgatgtc
ctggctgaggaggcagcagctacttctgctgaaaaaagtgctacagaatatgcagacagc
agcaaggcagataggaagcccttcattcctcaaatagaccacatagccaagtgcaagttg
gagctggctacaaaggcccagagtctccagaaatccttgaaactcatcatatttcaagtt
gaacaagctctggatgaggaaagcagacagacaatatctgttaagaactttagttcaact
ttcttcctggaagatgacccagaagatattaaccagacaagcccacgacgccgttctcgt
cgtggcactttgtcttctatatcttctctcaaaagtgaggacctggacaaccttaacttg
gatcacttacattttacacctgaatctatacgcttcaaagaaaaatgtgtcatgaacaac
tacttcggaattggactggatgctaaaatttctctggacttcaacaccagaagagatgaa
cacccagggcaatacaatagccgccttaagaacaagatgtggtatggccttctgggaacc
aaagaacttttgcagcgctcttacaggaaactggaagaacgagtgcatttggagtgtgat
ggagaaaccatctccttgccaaacctgcaaggcattgtagtgctcaacattaccagctat
gctggaggtatcaacttctggggaagcaacacagcaaccacggaatatgaggctcctgca
atcgatgatgggaaactggaggtggtggcaatctttggttctgtgcagatggcaatgtcc
cgtatcatcaacctgcatcatcatcgcattgcccagtgccatgaggtgatgataaccatt
gatggtgaagaaggtatcccagtgcaggtggatggggaggcctggattcagagaccaggc
cttatcaaaattagatacaagaacgctgcccagatgctgacaagagatcgggactttgag
aactcaatgaaaatgtgggaatacaagcatactgaaattcaagctgcccctcaaccccag
ctggacttccaggactctcaagagagcctctctgacgaggagtatgcccagatgcagcac
ttagctcggcttgcagaaaacctcatcagcaaacttaatgacctgagcaagatccaccag
catgtgtctgtcctcatgggttctgtgaatgccagcgctaacatcctgaatgatatattt
tacggccaagacagtggcaatgagatgggtgcagcttcctgtattcccattgaaactcta
agcagaaatgatgccgtagatgttacatttagtcttaaaggtctctacgatgacaccaca
gctttcctggatgaaaagctgctgagaagtgctgaggatgagactgcactacaaagcgcc
ctggatgccatgaataaggagttcaaaaagctatctgagattgactggatgaatccaatc
tttgttccagaggaaaaatcttcggacactgacagtagaagcctcaggctgaaaattaag
ttccccaaattgggaaagaaaaaggtagaagaggaacgcaagcctaaatcaggccagagt
gtccagagttttattggcaatttatggcaccgcagacatcgtgaagatgaagcagagggt
gatgatcctctaacaccatcgagatctcaactgtag

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