KEGG   Homo sapiens (human): 1392
Entry
1392              CDS       T01001                                 

Gene name
CRH, CRF, CRH1
Definition
(RefSeq) corticotropin releasing hormone
  KO
K05256  corticotropin-releasing hormone
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04730  Long-term depression
hsa04934  Cushing syndrome
hsa05034  Alcoholism
Network
nt06234  cAMP signaling
nt06310  CRH-ACTH-cortisol signaling
nt06360  Cushing syndrome
  Element
N00324  CRHR-PKA-ACTH signaling pathway
N00327  Mutation-inactivated PRKAR1A to CRHR-PKA-ACTH signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    1392 (CRH)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    1392 (CRH)
 09150 Organismal Systems
  09156 Nervous system
   04730 Long-term depression
    1392 (CRH)
 09160 Human Diseases
  09165 Substance dependence
   05034 Alcoholism
    1392 (CRH)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    1392 (CRH)
SSDB
Motif
Pfam: CRF
Other DBs
NCBI-GeneID: 1392
NCBI-ProteinID: NP_000747
OMIM: 122560
HGNC: 2355
Ensembl: ENSG00000147571
Vega: OTTHUMG00000164474
Pharos: P06850(Tbio)
CPD: C16079
UniProt: P06850 A0A0S2Z478
LinkDB
Structure
PDB: 
1GO9 1GOE

Position
8q13.1
AA seq 196 aa
MRLPLLVSAGVLLVALLPCPPCRALLSRGPVPGARQAPQHPQPLDFFQPPPQSEQPQQPQ
ARPVLLRMGEEYFLRLGNLNKSPAAPLSPASSLLAGGSGSRPSPEQATANFFRVLLQQLL
LPRRSLDSPAALAERGARNALGGHQEAPERERRSEEPPISLDLTFHLLREVLEMARAEQL
AQQAHSNRKLMEIIGK
NT seq 591 nt   +upstreamnt  +downstreamnt
atgcggctgccgctgcttgtgtccgcgggagtcctgctggtggctctcctgccctgcccg
ccatgcagggcgctcctgagccgcgggccggtcccgggagctcggcaggcgccgcagcac
cctcagcccttggatttcttccagccgccgccgcagtccgagcagccccagcagccgcag
gctcggccggtcctgctccgcatgggagaggagtacttcctccgcctggggaacctcaac
aagagcccggccgctcccctttcgcccgcctcctcgctcctcgccggaggcagcggcagc
cgcccttcgccggaacaggcgaccgccaactttttccgcgtgttgctgcagcagctgctg
ctgcctcggcgctcgctcgacagccccgcggctctcgcggagcgcggcgctaggaatgcc
ctcggcggccaccaggaggcaccggagagagaaaggcggtccgaggagcctcccatctcc
ctggatctcaccttccacctcctccgggaagtcttggaaatggccagggccgagcagtta
gcacagcaagctcacagcaacaggaaactcatggagattattgggaaataa

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