KEGG   Homo sapiens (human): 1431
Entry
1431              CDS       T01001                                 
Symbol
CS
Name
(RefSeq) citrate synthase
  KO
K01647  citrate synthase [EC:2.3.3.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00020  Citrate cycle (TCA cycle)
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Module
hsa_M00009  Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031  Citrate cycle and pyruvate metabolism
  Element
N01604  Citrate cycle, first carbon oxidation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    1431 (CS)
   00630 Glyoxylate and dicarboxylate metabolism
    1431 (CS)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.1  citrate (Si)-synthase
     1431 (CS)
SSDB
Motif
Pfam: Citrate_synt PAS_3 Queuosine_synth
Other DBs
NCBI-GeneID: 1431
NCBI-ProteinID: NP_004068
OMIM: 118950
HGNC: 2422
Ensembl: ENSG00000062485
Pharos: O75390(Tbio)
UniProt: O75390
Structure
LinkDB
Position
12:complement(56271699..56300330)
AA seq 466 aa
MALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVV
GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLF
WLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESN
FARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNF
TNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPL
HGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQ
REFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYY
TVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG
NT seq 1401 nt   +upstreamnt  +downstreamnt
atggctttacttactgcggccgcccggctcttgggaaccaagaatgcatcttgtcttgtt
cttgcagcccggcatgccagtgcttcctccacgaatttgaaagacatattggctgacctg
atacctaaggagcaggccagaattaagactttcaggcagcaacatggcaagacggtggtg
ggccaaatcactgtggacatgatgtatggtggcatgagaggcatgaagggattggtctat
gaaacatcagttcttgatcctgatgagggcatccgtttccgaggctttagtatccctgaa
tgccagaaactgctacccaaggctaagggtggggaagaacccctgcctgagggcttattt
tggctgctggtaactggacatatcccaacagaggaacaggtatcttggctctcaaaagag
tgggcaaagagggcagctctgccttcccatgtggtcaccatgctggacaactttcccacc
aatctacaccccatgtctcagctcagtgcagctgttacagccctcaacagtgaaagtaac
tttgcccgagcatatgcacagggtatcagccgaaccaagtactgggagttgatttatgaa
gactctatggatctaatcgcaaagctaccttgtgttgcagcaaagatctaccgaaatctc
tacagagaaggcagcggtattggggccattgactctaacctggactggtctcacaatttc
accaacatgttaggctatactgatcatcagttcactgagctcacgcgcctgtacctcacc
atccacagtgaccatgagggtggcaatgtaagtgcccataccagccatttggtgggcagt
gccctttccgacccttacctgtcctttgcagcagccatgaacgggctggcagggcctctc
catggactggcaaatcaggaagtgcttgtctggctaacacagctgcagaaggaagttggc
aaagatgtgtcagatgagaagttacgagactacatctggaacacactcaactcaggacgg
gttgttccaggctatggccatgcagtactaaggaagactgatccgcgatatacctgtcag
cgagagtttgctctgaaacacctgcctaatgaccccatgtttaagttggttgctcagctg
tacaagattgtgcccaatgtcctcttagagcagggtaaagccaagaatccttggcccaat
gtagatgctcacagtggggtgctgctccagtattatggcatgacggagatgaattactac
acggtcctgtttggggtgtcacgagcattgggtgtactggcacagctcatctggagccga
gccttaggcttccctctagaaaggcccaagtccatgagcacagagggtctgatgaagttt
gtggactctaagtcagggtaa

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