Homo sapiens (human): 1431
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Entry
1431 CDS
T01001
Symbol
CS
Name
(RefSeq) citrate synthase
KO
K01647
citrate synthase [EC:
2.3.3.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00020
Citrate cycle (TCA cycle)
hsa00630
Glyoxylate and dicarboxylate metabolism
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
hsa01210
2-Oxocarboxylic acid metabolism
hsa01230
Biosynthesis of amino acids
Module
hsa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hsa_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Network
nt06031
Citrate cycle and pyruvate metabolism
Element
N01604
Citrate cycle, first carbon oxidation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
1431 (CS)
00630 Glyoxylate and dicarboxylate metabolism
1431 (CS)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.1 citrate (Si)-synthase
1431 (CS)
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Gene cluster
GFIT
Motif
Pfam:
Citrate_synt
PAS_3
Queuosine_synth
Motif
Other DBs
NCBI-GeneID:
1431
NCBI-ProteinID:
NP_004068
OMIM:
118950
HGNC:
2422
Ensembl:
ENSG00000062485
Pharos:
O75390
(Tbio)
UniProt:
O75390
Structure
PDB
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Position
12:complement(56271699..56300330)
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AA seq
466 aa
AA seq
DB search
MALLTAAARLLGTKNASCLVLAARHASASSTNLKDILADLIPKEQARIKTFRQQHGKTVV
GQITVDMMYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKAKGGEEPLPEGLF
WLLVTGHIPTEEQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESN
FARAYAQGISRTKYWELIYEDSMDLIAKLPCVAAKIYRNLYREGSGIGAIDSNLDWSHNF
TNMLGYTDHQFTELTRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPL
HGLANQEVLVWLTQLQKEVGKDVSDEKLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQ
REFALKHLPNDPMFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYY
TVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTEGLMKFVDSKSG
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctttacttactgcggccgcccggctcttgggaaccaagaatgcatcttgtcttgtt
cttgcagcccggcatgccagtgcttcctccacgaatttgaaagacatattggctgacctg
atacctaaggagcaggccagaattaagactttcaggcagcaacatggcaagacggtggtg
ggccaaatcactgtggacatgatgtatggtggcatgagaggcatgaagggattggtctat
gaaacatcagttcttgatcctgatgagggcatccgtttccgaggctttagtatccctgaa
tgccagaaactgctacccaaggctaagggtggggaagaacccctgcctgagggcttattt
tggctgctggtaactggacatatcccaacagaggaacaggtatcttggctctcaaaagag
tgggcaaagagggcagctctgccttcccatgtggtcaccatgctggacaactttcccacc
aatctacaccccatgtctcagctcagtgcagctgttacagccctcaacagtgaaagtaac
tttgcccgagcatatgcacagggtatcagccgaaccaagtactgggagttgatttatgaa
gactctatggatctaatcgcaaagctaccttgtgttgcagcaaagatctaccgaaatctc
tacagagaaggcagcggtattggggccattgactctaacctggactggtctcacaatttc
accaacatgttaggctatactgatcatcagttcactgagctcacgcgcctgtacctcacc
atccacagtgaccatgagggtggcaatgtaagtgcccataccagccatttggtgggcagt
gccctttccgacccttacctgtcctttgcagcagccatgaacgggctggcagggcctctc
catggactggcaaatcaggaagtgcttgtctggctaacacagctgcagaaggaagttggc
aaagatgtgtcagatgagaagttacgagactacatctggaacacactcaactcaggacgg
gttgttccaggctatggccatgcagtactaaggaagactgatccgcgatatacctgtcag
cgagagtttgctctgaaacacctgcctaatgaccccatgtttaagttggttgctcagctg
tacaagattgtgcccaatgtcctcttagagcagggtaaagccaagaatccttggcccaat
gtagatgctcacagtggggtgctgctccagtattatggcatgacggagatgaattactac
acggtcctgtttggggtgtcacgagcattgggtgtactggcacagctcatctggagccga
gccttaggcttccctctagaaaggcccaagtccatgagcacagagggtctgatgaagttt
gtggactctaagtcagggtaa
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