Homo sapiens (human): 143686 Help Entry 143686            CDS       T01001                                  Symbol SESN3, SEST3 Name (RefSeq) sestrin 3   KO K10141   sestrin 1/3 Organism hsa  Homo sapiens (human) Pathway hsa04115   p53 signaling pathway hsa04211   Longevity regulating pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04115 p53 signaling pathway     143686 (SESN3)  09150 Organismal Systems   09149 Aging    04211 Longevity regulating pathway     143686 (SESN3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PA26 CMD PEX11 Motif Other DBs NCBI-GeneID:  143686 NCBI-ProteinID:  NP_653266 OMIM:  607768 HGNC:  23060 Ensembl:  ENSG00000149212 Pharos:  P58005(Tbio) UniProt:  P58005 LinkDB All DBs Position 11:complement(95165513..95232475) Genome browser AA seq 492 aa AA seqDB search MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTN FLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQ CSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKT GENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLAND NNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFV VSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHG FSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDY DYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAEL LYALRAITRHLT NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgaaccggggcggcggcagcccgtcggccgccgccaactacctgctctgtaccaactgc cggaaagtgctgcggaaggataaaagaatcagagtgtctcaacccttgacaagaggacca agtgcctttattccagagaaggaagttgtccaagcaaacacagtggatgaacgtactaac tttcttgtggaagaatactctacatccggtcgtctggacaacatcacacaggtcatgagt ttacacactcagtacctggagtctttcttgcggagccagttttacatgttgcgcatggat ggtccccttcctctaccatacaggcactatattgcaataatggctgcagctagacatcag tgttcttacttaataaacatgcatgtggatgaatttttaaagactggaggtattgctgag tggttgaatggtttggaatatgtgccacaaagactgaaaaatcttaatgaaattaataag ctgctagcacatcgaccttggctgatcacaaaagagcacattcagaaacttgtcaaaact ggagaaaataattggtctctgcctgaactggtacatgctgtggtcctcctggcacattat catgctttggcaagctttgtttttggtagtggtatcaatccagagagagatccagaaatc tccaatggattcaggctaatatcagtcaacaatttctgcgtttgtgatcttgctaatgac aacaacatagagaatgcatctctttcaggcagcaactttgggattgtggattctctaagt gagctagaggccttaatggaaaggatgaaaagacttcaagaagaaagggaagatgaagag gcgtctcaagaagaaatgagcactcgttttgaaaaggagaagaaagaaagtctttttgtg gtctctggagatacttttcattcatttcctcattcagattttgaggatgacatgattata acatctgatgtctctcgatatattgaagaccctggttttgggtatgaagactttgccaga cgaggagaagagcatttgccaacattccgagctcaggactatacctgggaaaatcatggg ttctccctggtgaacagactttattctgacattggacatcttcttgatgaaaagtttcgg atggtctacaatctcacatataacactatggccacccatgaggatgttgacacaaccatg ctgcgcagagctttatttaactatgttcactgtatgtttggaatcaggtatgatgactat gattatggagaagttaatcaattacttgaaagaagcctgaaggtttacattaagacagtg acctgctatcctgagagaactacaaaacgcatgtatgatagttactggcggcagttcaaa cactcagaaaaagttcatgtcaatctacttttaatggaagcacgaatgcaagctgaactt ctttatgctcttcgtgccataactcggcatttgacctga

Homo sapiens (human): 27244 Help Entry 27244             CDS       T01001                                  Symbol SESN1, PA26, SEST1 Name (RefSeq) sestrin 1   KO K10141   sestrin 1/3 Organism hsa  Homo sapiens (human) Pathway hsa04115   p53 signaling pathway hsa04211   Longevity regulating pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09143 Cell growth and death    04115 p53 signaling pathway     27244 (SESN1)  09150 Organismal Systems   09149 Aging    04211 Longevity regulating pathway     27244 (SESN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PA26 CMD Motif Other DBs NCBI-GeneID:  27244 NCBI-ProteinID:  NP_001186862 OMIM:  606103 HGNC:  21595 Ensembl:  ENSG00000080546 Pharos:  Q9Y6P5(Tbio) UniProt:  Q9Y6P5 LinkDB All DBs Position 6:complement(108984309..109094846) Genome browser AA seq 492 aa AA seqDB search MRLAAAANEAYTAPLAVSGLLGCKQCGGGRDQDEELGIRIPRPLGQGPSRFIPEKEILQV GSEDAQMHALFADSFAALGRLDNITLVMVFHPQYLESFLKTQHYLLQMDGPLPLHYRHYI GIMAAARHQCSYLVNLHVNDFLHVGGDPKWLNGLENAPQKLQNLGELNKVLAHRPWLITK EHIEGLLKAEEHSWSLAELVHAVVLLTHYHSLASFTFGCGISPEIHCDGGHTFRPPSVSN YCICDITNGNHSVDEMPVNSAENVSVSDSFFEVEALMEKMRQLQECRDEEEASQEEMASR FEIEKRESMFVFSSDDEEVTPARAVSRHFEDTSYGYKDFSRHGMHVPTFRVQDYCWEDHG YSLVNRLYPDVGQLIDEKFHIAYNLTYNTMAMHKDVDTSMLRRAIWNYIHCMFGIRYDDY DYGEINQLLDRSFKVYIKTVVCTPEKVTKRMYDSFWRQFKHSEKVHVNLLLIEARMQAEL LYALRAITRYMT NT seq 1479 nt NT seq  +upstreamnt  +downstreamnt atgcgcttggccgccgccgcgaacgaggcgtacacggcccctttggcggtctcggggctg ctgggctgcaagcagtgcggcgggggccgcgaccaggacgaggaacttggcattagaatt cctcgaccactaggacagggaccaagcagattcatcccagaaaaggagatcctccaagtg gggagtgaagacgcacagatgcatgctttatttgcagattcttttgctgctttgggccgt ttggataacattacgttagtgatggttttccacccacaatatttagaaagtttcttaaaa actcagcactatctactgcaaatggatgggccgttacccctacattatcgtcactacatt ggaataatggctgcggcaagacatcagtgctcctacttagtgaacctgcatgtaaatgat ttccttcatgttggtggggaccccaagtggctcaatggtttagagaatgctcctcaaaaa ctacagaatttaggagaacttaacaaagtgttagcccatagaccttggcttattaccaaa gaacacattgagggacttttaaaagctgaagagcacagctggtcccttgcggaattggta catgcagtagttttactcacacactatcattctcttgcctcattcacattcggctgtgga atcagtccagaaattcattgtgatggtggccacacattcagacctccttctgttagcaac tactgcatctgtgacattacaaatggcaatcacagtgtggatgagatgccggtcaactca gcagaaaatgtttctgtaagtgattctttctttgaggttgaagccctcatggaaaagatg aggcagttacaggaatgtcgagatgaagaagaggcaagtcaggaagagatggcttcacgt tttgaaatagaaaaaagagagagtatgtttgtcttctcttcagatgatgaagaagttaca ccagcaagagctgtatctcgtcattttgaggatactagttatggctataaagatttctct agacatgggatgcatgttccaacatttcgtgtccaggactattgctgggaagatcatggt tattctttggtaaatcgcctttatccagatgtgggacagttgattgatgaaaaatttcac attgcttacaatcttacttataatacaatggcaatgcacaaagatgttgatacctcaatg cttagacgggcaatttggaactatattcactgcatgtttggaataagatatgatgattat gactatggtgaaattaaccagctattggatcgtagctttaaagtttatatcaaaactgtt gtttgcactcctgaaaaggttaccaaaagaatgtatgatagcttctggaggcagttcaag cactctgagaaggttcatgttaatctgcttcttatagaagctaggatgcaagcagaactc ctttatgctctgagagccattacccgctatatgacctga

Homo sapiens (human): 83667 Help Entry 83667             CDS       T01001                                  Symbol SESN2, HI95, SES2, SEST2 Name (RefSeq) sestrin 2   KO K20394   sestrin 2 Organism hsa  Homo sapiens (human) Pathway hsa04115   p53 signaling pathway hsa04150   mTOR signaling pathway hsa04211   Longevity regulating pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04150 mTOR signaling pathway     83667 (SESN2)  09140 Cellular Processes   09143 Cell growth and death    04115 p53 signaling pathway     83667 (SESN2)  09150 Organismal Systems   09149 Aging    04211 Longevity regulating pathway     83667 (SESN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PA26 CMD Motif Other DBs NCBI-GeneID:  83667 NCBI-ProteinID:  NP_113647 OMIM:  607767 HGNC:  20746 Ensembl:  ENSG00000130766 Pharos:  P58004(Tbio) UniProt:  P58004 Structure PDB LinkDB All DBs Position 1:28259518..28282491 Genome browser AA seq 480 aa AA seqDB search MIVADSECRAELKDYLRFAPGGVGDSGPGEEQRESRARRGPRGPSAFIPVEEVLREGAES LEQHLGLEALMSSGRVDNLAVVMGLHPDYFTSFWRLHYLLLHTDGPLASSWRHYIAIMAA ARHQCSYLVGSHMAEFLQTGGDPEWLLGLHRAPEKLRKLSEINKLLAHRPWLITKEHIQA LLKTGEHTWSLAELIQALVLLTHCHSLSSFVFGCGILPEGDADGSPAPQAPTPPSEQSSP PSRDPLNNSGGFESARDVEALMERMQQLQESLLRDEGTSQEEMESRFELEKSESLLVTPS ADILEPSPHPDMLCFVEDPTFGYEDFTRRGAQAPPTFRAQDYTWEDHGYSLIQRLYPEGG QLLDEKFQAAYSLTYNTIAMHSGVDTSVLRRAIWNYIHCVFGIRYDDYDYGEVNQLLERN LKVYIKTVACYPEKTTRRMYNLFWRHFRHSEKVHVNLLLLEARMQAALLYALRAITRYMT NT seq 1443 nt NT seq  +upstreamnt  +downstreamnt atgatcgtggcggactccgagtgccgcgcagagctcaaggactacctgcggttcgccccg ggcggcgtcggcgactcgggccccggagaggagcagagggagagccgggctcggcgaggc cctcgagggcccagcgccttcatccccgtggaggaggtccttcgggagggggctgagagc ctcgagcagcacctggggctggaggcactgatgtcctctgggcgagtagacaacctggca gtggtgatgggcctgcaccctgactactttaccagcttctggcgcctgcactacctgctg ctgcacacggatggtcccttggccagctcctggcgccactacattgccatcatggctgcc gcccgccatcagtgttcttacctggtaggctcccacatggccgagtttctgcagactggt ggtgaccctgagtggctgctgggcctccaccgggcccccgagaagctgcgcaaactcagc gagatcaacaagttgctggcgcatcggccatggctcatcaccaaggaacacatccaggcc ttgctgaagaccggcgagcacacttggtccctggccgagctcattcaggctctggtcctg ctcacccactgccactcgctctcctccttcgtgtttggctgtggcatcctccctgagggg gatgcagatggcagccctgccccccaggcacctacaccccctagtgaacagagcagcccc ccaagcagggacccgttgaacaactctgggggctttgagtctgcccgcgacgtggaggcg ctgatggagcgcatgcagcagctgcaggagagcctgctgcgggatgaggggacgtcccag gaggagatggagagccgctttgagctggagaagtcagagagcctgctggtgaccccctca gctgacatcctggagccctctccacacccagacatgctgtgctttgtggaagaccctact ttcggatatgaggacttcactcggagaggggctcaggcaccccctaccttccgggcccag gattatacctgggaagaccatggctactcgctgatccagcggctttaccctgagggtggg cagctgctggatgagaagttccaggcagcctatagcctcacctacaataccatcgccatg cacagtggtgtggacacctccgtgctccgcagggccatctggaactatatccactgcgtc tttggcatcagatatgatgactatgattatggggaggtgaaccagctcctggagcggaac ctcaaggtctatatcaagacagtggcctgctacccagagaagaccacccgaagaatgtac aacctcttctggaggcacttccgccactcagagaaggtccacgtgaacttgctgctcctg gaggcgcgcatgcaagccgctctgctgtacgccctccgtgccatcacccgctacatgacc tga

DBGET integrated database retrieval system