Homo sapiens (human): 144193
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Entry
144193 CDS
T01001
Symbol
AMDHD1, HMFT1272
Name
(RefSeq) amidohydrolase domain containing 1
KO
K01468
imidazolonepropionase [EC:
3.5.2.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00340
Histidine metabolism
hsa01100
Metabolic pathways
Module
hsa_M00045
Histidine degradation, histidine => N-formiminoglutamate => glutamate
Network
nt06037
Histidine metabolism
Element
N01727
Histidine degradation 1
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
144193 (AMDHD1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.7 imidazolonepropionase
144193 (AMDHD1)
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Gene cluster
GFIT
Motif
Pfam:
Amidohydro_3
Amidohydro_1
Motif
Other DBs
NCBI-GeneID:
144193
NCBI-ProteinID:
NP_689648
HGNC:
28577
Ensembl:
ENSG00000139344
UniProt:
Q96NU7
B3KVC5
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All DBs
Position
12:95943331..95968720
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AA seq
426 aa
AA seq
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MASGHSLLLENAQQVVLVCARGERFLARDALRSLAVLEGASLVVGKDGFIKAIGPADVIQ
RQFSGETFEEIIDCSGKCILPGLVDAHTHPVWAGERVHEFAMKLAGATYMEIHQAGGGIH
FTVERTRQATEEELFRSLQQRLQCMMRAGTTLVECKSGYGLDLETELKMLRVIERARREL
DIGISATYCGAHSVPKGKTATEAADDIINNHLPKLKELGRNGEIHVDNIDVFCEKGVFDL
DSTRRILQRGKDIGLQINFHGDELHPMKAAELGAELGAQAISHLEEVSDEGIVAMATARC
SAILLPTTAYMLRLKQPRARKMLDEGVIVALGSDFNPNAYCFSMPMVMHLACVNMRMSMP
EALAAATINAAYALGKSHTHGSLEVGKQGDLIIINSSRWEHLIYQFGGHHELIEYVIAKG
KLIYKT
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atggcaagcggccacagcctcctgctggagaacgcgcagcaagtggtgctggtgtgcgcc
cgcggcgagcgcttcctggcgcgggatgcgctgcgcagcctggcggtgctggaaggcgcc
agcctggtggtgggcaaagatggatttataaaagctattggtcctgctgatgttattcaa
agacagttttctggagaaacttttgaagaaataattgactgctctgggaaatgtattcta
ccaggtttggtggatgcacacacacatccagtatgggctggtgaaagagttcacgaattt
gcaatgaagttggcaggagccacctacatggaaattcaccaggccggaggagggatccac
tttaccgtggagcgcacgcgccaagccacagaggaggagctgttccgctccttgcagcaa
cggctccagtgcatgatgagggctggcaccacgctggtggagtgcaagagtggatatggc
ctcgacctggagaccgagctcaagatgctgcgcgtgattgagcgcgcccggcgggagctg
gacatcggcatctcggctacctactgcggggctcattcagtgcctaaaggaaaaactgct
actgaagctgctgatgacatcatcaataaccacctcccaaagctgaaggaacttggcaga
aatggggaaatacacgtggacaatatagacgtattttgtgagaaaggtgtctttgatctc
gattccaccagaaggattcttcaacgtggaaaagatatagggttacagattaacttccat
ggggatgaactccacccgatgaaggctgctgagcttggggctgaactgggagcgcaggca
atcagccacctggaagaagtgagtgatgaaggcatcgttgccatggcaacggccaggtgc
tctgccatccttctgcccaccacagcctacatgctgagactgaaacaacctcgagccagg
aagatgttagatgaaggagtaatagttgctctgggaagtgatttcaaccccaatgcatat
tgcttttcaatgccaatggtcatgcatctggcctgtgtaaacatgagaatgtccatgcct
gaggccttggccgctgccaccatcaatgcagcttatgcactgggaaagtctcacacacac
ggatcgttggaagttggcaaacagggagatctcattatcatcaattcatcccgatgggag
catttgatttaccagttcggaggccatcatgaattaattgaatatgttatagctaaagga
aaactcatctataaaacatga
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