KEGG   Homo sapiens (human): 144811
Entry
144811            CDS       T01001                                 
Symbol
LACC1, C13orf31, FAMIN, JUVAR
Name
(RefSeq) purine nucleoside phosphorylase LACC1 isoform 1
  KO
K05810  purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa00270  Cysteine and methionine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Module
hsa_M00034  Methionine salvage pathway
hsa_M00958  Adenine ribonucleotide degradation, AMP => Urate
hsa_M00959  Guanine ribonucleotide degradation, GMP => Urate
Network
nt06027  Purine salvage pathway
  Element
N01418  Purine salvage pathway, adenine to AMP
N01421  Purine salvage pathway, hypoxanthine/guanine to IMP/GMP
Disease
H01672  Juvenile idiopathic arthritis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    144811 (LACC1)
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    144811 (LACC1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.1  purine-nucleoside phosphorylase
     144811 (LACC1)
    2.4.2.28  S-methyl-5'-thioadenosine phosphorylase
     144811 (LACC1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.4  adenosine deaminase
     144811 (LACC1)
SSDB
Motif
Pfam: Cu-oxidase_4
Other DBs
NCBI-GeneID: 144811
NCBI-ProteinID: NP_001121775
OMIM: 613409
HGNC: 26789
UniProt: Q8IV20
LinkDB
Position
13:43879178..43893932
AA seq 430 aa
MAEAVLIDLFGLKLNSQKNCHQTLLKTLNAVQYHHAAKAKFLCIMCCSNISYERDGEQDN
CEIETSNGLSALLEEFEIVSCPSMAATLYTIKQKIDEKNLSSIKVIVPRHRKTLMKAFID
QLFTDVYNFEFEDLQVTFRGGLFKQSIEINVITAQELRGIQNEIETFLRSLPALRGKLTI
ITSSLIPDIFIHGFTTRTGGISYIPTLSSFNLFSSSKRRDPKVVVQENLRRLANAAGFNV
EKFYRIKTHHSNDIWIMGRKEPDSYDGITTNQRGVTIAALGADCIPIVFADPVKKACGVA
HAGWKGTLLGVAMATVNAMIAEYGCSLEDIVVVLGPSVGPCCFTLPRESAEAFHNLHPAC
VQLFDSPNPCIDIRKATRILLEQGGILPQNIQDQNQDLNLCTSCHPDKFFSHVRDGLNFG
TQIGFISIKE
NT seq 1293 nt   +upstreamnt  +downstreamnt
atggcagaagctgttttgattgatctttttggtttgaaattgaactctcaaaaaaactgc
catcagacattactgaagactttgaatgctgtccaataccaccatgctgccaaggccaag
tttctctgtataatgtgttgcagtaacatcagctatgaaagggatggagaacaagataat
tgtgaaatagaaacaagcaatggattatcagctctcttggaagaatttgagattgttagc
tgtcccagcatggctgccactttgtataccattaaacagaaaattgatgaaaaaaatctg
agcagcattaaggtaattgtacccaggcacaggaagacattaatgaaagcttttattgat
caactcttcactgatgtttacaattttgaatttgaagatttgcaagtgacttttagggga
gggctttttaaacagtccattgaaataaacgtaatcacagctcaagaactaagaggaatt
cagaatgaaatagaaacatttttgagaagtctgccagcactgagaggaaaattaactatt
atcacttcttctttgatcccagatattttcatacatggatttactacaagaacaggtggg
atatcttatataccaactcttagctcattcaatctcttcagtagttccaaacggagagat
cccaaggtagtggttcaagaaaatctgcgtaggttggcgaatgctgcaggatttaatgtg
gagaaattttaccgaataaagactcatcattccaatgacatctggattatgggaagaaag
gagcctgactcttatgatggaataaccacaaatcagagaggagtcacaatagcagctctt
ggtgcagactgtataccgatagtttttgcagatccagtcaaaaaagcatgtggggttgct
cacgctggttggaaaggtactttgttgggtgttgctatggctacagtgaatgctatgata
gcagaatatggctgcagtttggaagacattgttgttgtacttggaccttcagtaggacct
tgctgttttactcttccaagggaatcagcagaggcatttcataatcttcatcctgcatgt
gtacaactatttgattcaccaaatccctgtatcgacatccgtaaagccacaaggattctt
ctagaacagggaggaattcttccacagaatattcaggaccagaaccaagatctcaacctc
tgtacatcttgccatcctgacaagtttttctcccatgtccgagatggccttaattttggt
acacagattggcttcatatcaattaaagaatga

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