Homo sapiens (human): 146057
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Entry
146057 CDS
T01001
Symbol
TTBK2, SCA11, TTBK
Name
(RefSeq) tau tubulin kinase 2
KO
K08815
tau tubulin kinase [EC:
2.7.11.26
]
Organism
hsa
Homo sapiens (human)
Disease
H00063
Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
146057 (TTBK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.26 tau-protein kinase
146057 (TTBK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CK1 group
TTBK family
146057 (TTBK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
146057
NCBI-ProteinID:
NP_775771
OMIM:
611695
HGNC:
19141
Ensembl:
ENSG00000128881
UniProt:
Q6IQ55
Q8IWY7
Structure
PDB
PDBj
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All DBs
Position
15:complement(42738730..42921000)
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AA seq
1244 aa
AA seq
DB search
MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQV
LKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLR
LGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPP
RAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKE
RYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKT
GNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIP
VGVSPDKLPGSLGHPRPQEKDVWEEMDANKNKIKLGICKAATEEENSHGQANGLLNAPSL
GSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCLEKMQKDTSA
GKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASKPASANTPEQADGGGSNGFIAVNL
SSCKQEIDSKEWVIVDKEQDLQDFRTNEAVGHKTTGSPSDEEPEVLQVLEASPQDEKLQL
GPWAENDHLKKETSGVVLALSAEGPPTAASEQYTDRLELQPGAASQFIAATPTSLMEAQA
EGPLTAITIPRPSVASTQSTSGSFHCGQQPEKKDLQPMEPTVELYSPRENFSGLVVTEGE
PPSGGSRTDLGLQIDHIGHDMLPNIRESNKSQDLGPKELPDHNRLVVREFENLPGETEEK
SILLESDNEDEKLSRGQHCIEISSLPGDLVIVEKDHSATTEPLDVTKTQTFSVVPNQDKN
NEIMKLLTVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFL
HQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEIDSTLESSS
PVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPAPFCEEEVL
TPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPG
KPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTP
PKSPVVPRRSPSASPRSSSLPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSS
RRSCQQEHCKPSKNGLKGSGSLHHHSASTKTPQGKSKPASKLSR
NT seq
3735 nt
NT seq
+upstream
nt +downstream
nt
atgagtgggggaggagagcagctggatatcctgagtgttggaatcctagtgaaagaaaga
tggaaagtgttgagaaagattgggggtgggggctttggagaaatttacgatgccttggac
atgctcaccagggaaaatgttgcactgaaggtggaatcagctcaacaaccaaaacaagtt
ctgaaaatggaagttgctgttttgaaaaagctgcaagggaaagaccatgtttgtagattt
attggctgtgggaggaatgatcgattcaactatgtggtcatgcagttgcagggtcggaat
ctggcagatcttcgccgtagccagtcccgaggcacattcaccattagtaccactctccgg
ctgggtagacagattttggagtctattgaaagcattcattctgtgggattcttgcatcga
gacatcaaaccgtcgaacttcgctatgggtcgctttcctagtacatgtaggaaatgttac
atgcttgattttggcttggctcgacaatttaccaattcctgtggtgacgtcagaccacct
cgagctgtggcaggttttcgagggacagttcgttatgcatcaatcaacgcacatcggaac
agggaaatgggaagacatgatgacctttggtccttattctacatgttggtggagtttgtg
gttggtcagctgccctggagaaaaataaaggacaaggagcaagtaggctctattaaggag
agatatgaccacaggctcatgttgaaacatctccctccagaattcagcatctttctagac
catatctcttctttggattattttacaaaaccagactaccagcttcttacatccgtgttt
gacaatagcatcaagacttttggagtaattgagagtgacccttttgactgggagaagact
ggaaatgatggctccctaacaaccaccactacttctaccacccctcagttgcacactcgc
ttgacccctgctgcaattggaattgccaatgctactcccatccctggagacttgcttcga
gaaaatacagatgaggtatttccagatgaacagcttagcgatggagaaaatggcatccct
gttggtgtgtcaccagataaattgcctggatctctgggacacccccgtccccaggagaag
gatgtttgggaagagatggatgccaacaaaaacaagataaagcttggaatttgtaaggct
gctactgaagaggagaacagccatggccaggcaaatggtcttctcaatgctccaagcctt
gggtcaccaattcgtgtccgctcagagattactcagccagacagagatattccactggtg
cgaaagttacgttccattcacagctttgagctggaaaaacgtctgaccctggagccaaag
ccagacactgacaagttccttgagacctgcctggagaaaatgcagaaagataccagtgca
ggaaaagaatctattctccctgctctgctgcataagccttgcgttcctgctgtgtcccgt
actgaccacatctggcactatgatgaagaatatcttccagatgcctccaagcctgcttct
gccaacacccctgagcaggcagatggtggtggcagcaatggatttatagctgttaacctg
agctcttgcaagcaagaaattgattccaaagaatgggtgattgtggacaaggagcaggac
cttcaggattttaggacaaatgaggctgtaggacataaaacaactggaagtccttctgat
gaggagcctgaagtacttcaagtcctggaggcatcacctcaagatgaaaagctccagtta
ggtccttgggcagaaaatgatcatttaaagaaggaaacctcaggtgtggtcttagcactt
tctgcagagggtcctcctactgctgcttcagaacaatatacagataggctggaactccag
cctggagctgctagtcagtttattgcagcgacgcccacaagtctaatggaggcgcaggca
gaaggaccccttacagcgattacaattcctagaccttctgtggcatctacacagtcaact
tcaggaagctttcactgtggtcagcagccagagaagaaagatcttcagcccatggagccc
actgtggaactttactctccaagggaaaacttctctggcttggttgtgacagagggtgaa
cctcctagtggaggaagcagaacagatttggggcttcagatagatcacattggtcatgac
atgttacccaacattagagaaagtaacaaatctcaagacctgggaccaaaagaacttcct
gatcataatagactggttgtgagagaatttgaaaatctccctggggaaactgaagagaaa
agcatccttttagagtcagataatgaagatgagaagttaagtagagggcagcattgtatt
gagatctcctctctcccaggagatttggtaattgtggaaaaggatcactcagctactact
gaacctcttgatgtgacaaaaacacagacttttagtgtggtgccaaatcaagacaaaaat
aatgagataatgaagcttctgacagttggaacttcagaaatttcttccagagacattgac
ccacatgttgaaggtcagataggccaagtggcagaaatgcaaaaaaataagatatctaag
gatgatgacatcatgagtgaagacttgccaggtcatcaaggagacctctctacttttttg
caccaagagggcaagagagagaaaatcacccctagaaatggagaactatttcattgtgtt
tcagagaatgaacatggtgccccaacccggaaggatatggttaggtcatcctttgtaact
agacacagccgaatccctgttttagcacaagagatagactcaactttggaatcatcctct
ccagtttctgcaaaagaaaagctcctccaaaagaaagcctatcagccagacctagtcaag
cttctggtggaaaaaagacaattcaagtccttccttggcgacctctcaagtgcctctgat
aaattgctagaggagaaactagctactgttcctgctcccttttgtgaggaggaagtgctc
actcccttttcaagactgacagtagattctcacctgagtaggtcagctgaagatagcttt
ctgtcacccatcatctcccagtctagaaagagcaaaattccaaggccagtttcatgggtc
aacacagatcaggtcaatagctcaacttcgtctcagttctttcctcggccaccaccagga
aagccacccacgaggcctggagtagaagccaggctacgcagatataaagtcctagggagt
agtaactccgactcagaccttttctcccgcctggcccaaattcttcaaaatggatctcag
aaaccccggagcactactcagtgcaagagtccaggatctcctcacaatccaaaaacacca
cccaagagtccagttgtccctcgcaggagtcccagtgcctctcctcgaagctcatccttg
cctcgcacgtctagttcctcaccatctagggctggacggccccaccatgaccagaggagt
tcgtccccacatctggggagaagcaagtcacctcccagccactcaggatcttcctcctcc
aggaggtcctgccaacaggagcattgcaaacccagcaagaatggcctgaaaggatccggc
agcctccaccaccactcagccagcactaaaaccccccaagggaagagtaagccagccagt
aaactcagcagatag
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integrated database retrieval system
