KEGG   Homo sapiens (human): 146754
Entry
146754            CDS       T01001                                 
Symbol
DNAH2, DNAHC2, DNHD3, SPGF45
Name
(RefSeq) dynein axonemal heavy chain 2
  KO
K10408  dynein axonemal heavy chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
Network
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160  Mutation-caused aberrant SOD1 to retrograde axonal transport
Disease
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    146754 (DNAH2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    146754 (DNAH2)
   05016 Huntington disease
    146754 (DNAH2)
   05022 Pathways of neurodegeneration - multiple diseases
    146754 (DNAH2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    146754 (DNAH2)
   04812 Cytoskeleton proteins [BR:hsa04812]
    146754 (DNAH2)
Cilium and associated proteins [BR:hsa03037]
 Motile cilia and associated proteins
  Dynein arm
   146754 (DNAH2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     146754 (DNAH2)
SSDB
Motif
Pfam: AAA_6 DHC_N2 DHC_N1 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 DYN_lid AAA AAA_22 AAA_16 Mg_chelatase Sigma54_activat nSTAND3 NB-ARC HrcA Sigma54_activ_2 DUF3452 AAA_2 Bac_DnaA ATP_bind_1 ResIII Guanylate_kin
Other DBs
NCBI-GeneID: 146754
NCBI-ProteinID: NP_065928
OMIM: 603333
HGNC: 2948
Ensembl: ENSG00000183914
Pharos: Q9P225(Tdark)
UniProt: Q9P225
Structure
LinkDB
Position
17:7717744..7833742
AA seq 4427 aa
MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLE
GPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDP
CFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFA
PQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKE
LVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGV
KHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSK
LPKLISLIRIIWVNSPHYNTRERLTSLFRKVCDCQYHFARWEDGKQGPLPCFFGAQGPQI
TRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFE
LVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPY
VAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQ
EWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVN
VAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALK
GASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEED
QREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNV
KWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHL
FSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWD
MYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHL
KFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDA
LKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKK
HKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEE
NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETM
ETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVR
DEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQL
DIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVI
EMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHP
GLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLK
KCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVT
LRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILK
VMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWL
SQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGS
PKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRI
NIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLK
SMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRAL
TSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVID
YGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQAS
LSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPD
EKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVS
RCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPE
YSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSY
LREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNY
LVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIES
RVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIK
YIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEE
VKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSI
TRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEP
KVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLL
VGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFV
DTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIE
RVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLG
TQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQEL
LAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQ
KAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPP
AQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPD
FQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEK
LREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGL
EEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCN
PTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQ
MSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTN
FRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVIN
IAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINT
DLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRID
YLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREG
QMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWE
NACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFI
LSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSL
SWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRL
YQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENL
LSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSA
LETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQI
TPTRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLM
QTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMR
VEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSN
LVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYS
CPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS
NT seq 13284 nt   +upstreamnt  +downstreamnt
atgtccagcaaagctgagaagaagcagcgattgagtggccgaggaagctcccaggcaagc
tggtcagggcgggccactcgggctgctgtggccacacaggagcaggggaatgccccggct
gtcagtgagccagagctgcaggctgagctccccaaggaggagcctgagccacggttggag
ggacctcaagcacagagtgaagaatcagtggagcccgaggcagatgtgaagcccctcttc
ctttcccgagctgcgctgacaggactggcggatgcagtgtggacacaggagcatgatgcc
attctggaacactttgcccaggaccctacagaatccatcctcaccatcttcattgaccct
tgttttgggctgaagctagagctgggcatgcctgtacagacccagaaccagcttgtctac
ttcattcgccaagcaccagttcccatcacctgggagaacttcgaggcaactgtgcagttt
gggacggtgcggggcccctatatcccggccctgcttcggctgctcggtggagtctttgcc
cctcagatctttgcaaacacaggctggcctgagagcattagaaatcattttgcttctcat
ctgcacaagttcttggcctgcctgacagacactcggtacaaactggaggggcacacggtc
ctctacatccctgcagaggccatgaacatgaagcctgagatggtgataaaggacaaagag
ctggtgcaacggctagagacctccatgatccactggacccggcagataaaggagatgctc
agtgcccaggagactgtggagacaggagaaaatttaggtcctctggaggagattgagttc
tggcgcaaccgatgcatggacctgtctggcatcagtaagcagctggtgaagaagggagtg
aagcacgttgaatccatcctgcaccttgccaagtcgtcctacttggcgccctttatgaaa
ctggcacagcagatccaggatggctctcgtcaagcacagtcaaacctgacctttttgtca
atcctgaaggaaccttaccaggagttggctttcatgaagcccaaggacatctctagcaag
ctccctaagctgatcagtctcatccgcatcatctgggtcaactctccccactacaacact
cgggagagactgacctcgctcttccgaaaggtatgtgactgtcagtatcacttcgcccgc
tgggaagatggcaagcagggtccccttccttgcttctttggtgcccaggggccacagata
acacggaacttgctggagattgaggacatctttcataaaaatctgcacacgctgcgagcc
gttcgcgggggtatcctggatgtcaagaacacctgttggcatgaagactacaataagttc
cgtgccggaatcaaggacctggaggtgatgacccagaacctgatcacctcagccttcgag
ttggtgcgggacgtgccgcacggcgtgcttctgctggacaccttccacaggcttgcctcc
cgcgaggctatcaagcggacttatgacaagaaggcggtggatctctacatgctgttcaat
agcgagctggccctggtgaaccgtgaacggaacaagaaatggccagacctggagccctac
gtggcccagtattccggaaaggcgcgctgggtgcacatcctccggcgtcgcatcgacaga
gtcatgacctgccttgctggtgctcatttcctgccccgtattgggactggaaaggagagt
gtgcacacctatcagcagatggtccaggccattgatgagctggttcgaaaaaccttccaa
gagtggacatcaagtctggacaaggattgcattcggcggttggataccccattgctgcga
atcagccaggagaaggcgggcatgctggatgtcaactttgacaagtcccttctgattctc
tttgcggaaattgactactgggagcggctgctgtttgagacgccccattacgtggtgaac
gtagctgagcgagccgaggacctgcgcattctgcgtgaaaatctgctactcgttgctaga
gactacaataggattattgccatgctgtccccagatgagcaggccctattcaaagagcgt
attcggctcctggataagaagatccacccgggactcaagaaactgcactgggccttgaag
ggggccagtgccttcttcatcacggagtgccgtatacatgccagcaaggtgcagatgatt
gtgaatgagttcaaggcatccactctgaccattggctggcgagcccaagagatgtcagag
aagctgctggtacgcattagtggcaaacgggtatacagggacctggaatttgaagaggac
caaagagagcatcgggcagctgtacagcagaaattgatgaacctgcaccaggatgtggtg
accatcatgaccaactcctatgaggtcttcaagaatgatggtcctgagattcagcagcag
tggatgctgtacatgattcggctggaccgcatgatggaggatgccctgcgcctgaatgtg
aagtggtcactgctagaactatccaaggctatcaacggggatggaaagaccagcccaaac
ccactcttccaagtccttgtcattttgaagaatgatctgcaaggaagtgtggcacaggtg
gaattctcacccactctgcagactttggcaggtgtggtcaatgacattggcaaccacctc
ttttccaccatctctgtcttctgccacctccctgacattctcaccaagcgcaagttacat
cgtgaacccatccaaacagttgtggagcaagatgaggacatcaagaagatccagacccaa
atcagcagcggcatgactaacaacgcaagcctgctgcagaactacctcaagacctgggac
atgtaccgggagatctgggagatcaacaaggactccttcattcatcgctaccagcgcctc
aaccctcctgtctcttcttttgttgccgacattgcccgctacacggaagttgctaataac
gtgcagaaggaggagacagtcaccaacatccagtttgtgctgctggactgttcgcacctc
aagttctccctggtgcagcactgcaatgaatggcagaacaagttcgcgactctgctcagg
gagatggctgctgggcgcctcctggagctgcacacctacctgaaggagaacgcagagaaa
atcagccgccctccgcagacactggaggaactgggggtcagcttgcagctcgtggatgcc
ctgaagcacgacttggccaacgtggagactcagatccctcccatacacgagcaatttgcc
attcttgaaaagtacgaggtgccagtcgaggacagtgtcctggagatgctggacagtctc
aacggggagtgggttgtcttccaacaaactctgctggacagtaagcaaatgctgaagaaa
cacaaggagaaattcaagacaggcctgatccactcggcagatgacttcaagaagaaagca
catacacttctggaagatttcgaattcaaaggccatttcaccagcaacgtgggatacatg
tctgccttagaccagattacacaagtgcgggccatgctgatggccatgcgggaagaggaa
aatagtctccgagccaacctgggcatcttcaagatcgagcagccaccctccaaggacctt
cagaacctggagaaggagctcgatgccctccagcaaatctgggagatcgcacgagactgg
gaggagaactggaatgagtggaagactggccggttcctgatcctgcagacggaaaccatg
gagaccacggcccacgggctgtttcgtcgcctcacaaaattagccaaagagtataaggac
cgaaactgggaaattattgaaaccactcgctcaaaaatagagcagttcaagaggaccatg
cctctcatctcagacctgcggaaccctgcccttagagagaggcactgggaccaggtccgg
gatgagatccagcgggagtttgatcaggaatctgaaagcttcaccttggagcagattgtg
gagcttgggatggatcagcatgtggagaaaattggggagatctctgcttcagcaactaaa
gagctggctatagaagtggctttacaaaacattgccaagacctgggatgtgactcagctc
gacatagtaccctacaaggataagggccatcatcggctcagaggtacagaagaagtattc
caggcactggaagataaccaggtagctctgtctaccatgaaggcatcacgctttgtcaag
gcctttgagaaggatgtggaccactgggaacgctgcctctccctcattttggaggttatt
gagatgattctcacagtgcagcgtcagtggatgtacttagagaatatcttcctaggagaa
gacatccgcaagcagctgcccaatgaatcgaccttatttgaccaggtcaacagcaactgg
aaagccatcatggacaggatgaacaaggacaacaatgctctccggagcacccatcaccca
ggcctcctggacacattgatagaaatgaatacaatcctggaagatattcagaaatctctg
gatatgtatttagagaccaagcgacatattttcccccgcttctacttcttgtccaatgat
gacctgctggagattctgggccagtcccgaaacccagaggctgtgcagccacacctcaaa
aaatgctttgacaacatcaagttgctgagaatccagaaggttggagggcccagcagcaaa
tgggaagctgtggggatgttctcgggcgacggcgagtacattgacttcctccactcagta
tttttagaaggccctgtggagtcctggcttggcgatgtggaacagaccatgagggtgacc
ctgcgggaccttctccggaactgccacctggccctcaggaagttcctcaacaagagggac
aaatgggtgaaggagtgggctggccaggtggtgatcactgccagtcagatccagtggacg
gctgatgtcaccaagtgcctgctgacagcgaaggagcgggcagacaagaaaatcctcaag
gtcatgaagaagaaccaggtgtcaatcctgaataagtattcagaagccatcagggggaac
ttgaccaagatcatgcggcttaaaattgtggctctggtgacgatagaaattcatgcccgg
gatgtgttggagaagctttacaagagtggcctcatggatgtcaattcctttgactggctc
agccaacttcggttctactgggagaaggatcttgatgactgtgtcatccgccagaccaac
acgcaatttcagtataattatgagtacttgggtaactcgggccggctcgtcatcaccccc
ctgacggacaggtgttacatgacactgaccacggcattgcacctgcaccgagggggctcc
cccaaaggccctgcaggcacaggcaagaccgagaccgtcaaggacctgggcaaggccctg
ggcatatatgtcattgtggtcaactgctctgagggcctggactacaagtccatgggccga
atgtactcaggtctggcccagactggagcttggggctgctttgatgagtttaaccgcatc
aacatcgaggtgctgtcagtggtggcccaccagatcctgtgcatcctgtctgccctggct
gccggcctcacccatttccattttgatggctttgaaataaatctggtgtggtcctgtggg
atcttcattaccatgaatcctggctatgctggccgcacagagcttcccgaaaatcttaaa
tccatgttccgcccaattgccatggtggtgcctgactccaccctcattgcagaaatcatt
ctctttggagagggctttggcaactgcaagattctggccaagaaggtgtacacactctac
tcactggctgtgcagcagctgtccagacaggaccactatgactttggcctgcgtgccctc
acctcccttctgcgctatgctggcaagaagcgccgcctacagccggatctgactgatgaa
gaggttctgctgctctcaatgagagatatgaacatcgccaagctcacttcagttgatgca
cccctgttcaatgccatcgtgcaagatctgtttcccaacattgagctgcctgtcattgac
tatggcaagctgcgggagaccgttgagcaggagattcgagacatgggcctgcaaagcacg
ccgttcaccctcaccaaggttttccagttgtatgaaaccaagaactcccgccactccacc
atgatcgtgggctgcacgggcagcggcaagactgcctcatggcgcattctacaggcctcc
ctgtcctctctgtgccgcgccggagaccctaacttcaacattgttagagagttccctttg
aaccccaaggcattgtccctaggggaactgtatggggaatatgacctcagcaccaatgaa
tggacagatggcatcttgtccagtgtcatgcggacggcatgtgcagatgagaaacccgac
gagaagtggatcctgttcgatggccccgtggacacactgtggatcgagaacatgaactcc
gtcatggacgataacaaggtgttgaccctcatcaacggcgagcgcatcgcgatgcccgag
caggtgtctctcctgtttgaagtggaggacctggcaatggcctctccggccactgtatcc
cgctgcgggatggtctacactgactacgctgacctgggctggaagccctatgttcagtca
tggctggagaagaggccaaaggctgaggtggagccccttcaacgcatgttcgaaaagctc
atcaacaagatgctggcctttaagaaggacaactgcaaggagctggtgcccctgcccgag
tacagcggtatcacctccctctgcaagctgtactctgccctggccacgccagagaatggg
gtgaacccagctgacggcgagaactatgtcaccatggtagagatgacatttgtgttcagc
atgatctggtctgtgtgtgcctctgtggatgaggagggccggaagaggatcgacagctac
ctccgagagatcgagggctcctttcccaataaggacacggtatatgagtattttgtggac
cccaaaatacggagttggacatcatttgaggacaagctccctaagagttggcgctaccct
ccaaacgcccccttctataagatcatggtgcccaccgtcgacactgttcgctacaactac
ctggtgagcagcttggtggccaaccagaatcccattctgctggtgggtcccgtggggact
gggaagacctccatcgcccagagcgttctgcagtccctgccctccagccagtggtcggtg
ctcgttgtcaacatgtccgcacagaccacatccaataacgtgcagagcatcattgagagc
agggttgagaagcgaaccaagggtgtctacgtgccattcgggggcaaaagcatgatcacc
tttatggatgacctaaatatgcccgctaaggacatgtttgggtcccagccacccctggag
ctgatccgcctctggattgactatggcttctggtatgaccgtacgaagcagaccatcaag
tacattcgagaaatgttcctgatggctgccatgggcccccctgggggtggacggactgtc
atctccccaaggctacggagtcgcttcaacattatcaacatgaccttccccacaaagtcc
cagatcatccgcatattcggcaccatgatcaatcagaagcttcaggactttgaggaagag
gtgaagcccattgggaacgtggtgacagaggccaccctggacatgtacaacaccgtggta
cagcgcttcctgcccacgcccaccaagatgcattacctcttcaaccttcgagacatctcc
aaggtgttccagggcatgcttagagccaacaaggacttccatgataccaagtccagcatc
acacggctctggatccatgaatgtttcagagtcttctctgaccggctggttgatgcggca
gacacagaagccttcatgggcatcataagcgacaagctcggctccttctttgacctcaca
tttcatcatctctgtcccagcaagcgtcctcctatctttggggatttcctgaaggagccc
aaggtgtatgaagacctcacggatctgacagtgctgaagacagtcatggagacagctcta
aatgagtataacctgtcaccctctgtcgtgcccatgcagctagtgctcttccgagaggct
attgaacacatcacacggatcgtgcgggtcattggacagcctcggggcaacatgctcctg
gtgggtatcgggggcagcggacgccagagtctggcccgcctggcttcatccatctgcgac
tacaccaccttccagatcgaggtcaccaaacattatcggaagcaggagttccgagatgat
atcaagcgtctgtatcgccaggctggggtggagctcaagaccacgtccttcatttttgtg
gacacccaaatagctgatgagtccttcctagaggacatcaacaacatcctcagctcaggc
gaggtgcccaatctctacaagcctgatgaatttgaagagatccagtcgcatatcatagac
caggcccgggtggagcaggtgcctgagtcatcggacagcctcttcgcctacctcattgaa
cgcgtgcagaacaacctgcacatcgtgctctgcctcagccccatgggggatcccttcagg
aactggatccgccagtacccagccttggtgaactgcacaaccatcaactggttctcagag
tggccccaagaggccctgctcgaggtggctgagaagtgcctcataggagtagacctggga
actcaggagaatatccacaggaaggtggcccagatctttgtcactatgcactggtcagta
gctcagtattcccagaagatgctgttggaactgcggagacacaactatgtcacacccacc
aaatacctggaactcctgtctggatataagaagttgctgggagaaaaacggcaggagctg
ctggcccaagccaataaactgcggacaggcttgttcaagatcgacgaaactagggaaaag
gtgcaagtgatgtcgttggagctggaggatgccaagaagaaggtggctgagttccagaag
cagtgtgaggagtacctggtcatcattgtgcagcagaagcgggaggcagatgagcagcag
aaggccgtaacagccaacagtgaaaagattgcagttgaggaaatcaagtgtcaggcactg
gctgacaatgcccagaaagatctagaagaggcactgcccgccctggaagaggccatgcgg
gccctggagtctctgaacaagaaggatataggagagatcaagtcttatggacggccccca
gcccaagtggagatagtgatgcaggcagttatgattcttcgaggcaacgagcccacatgg
gcagaggccaagaggcagctaggggaacagaacttcatcaagtcactgatcaactttgat
aaagacaatatctcagataaggttctgaagaagattggggcctactgcgcccagcctgac
ttccagcctgatatcatcggccgcgtctccctggctgccaagtccctctgcatgtgggtg
cgggccatggagctgtatgggcggctatatcgggtggtggagcccaagcgaatccgaatg
aacgctgccttggctcagcttcgggagaagcaagccgcgctcgctgaggcccaggagaag
ctgcgggaggtagctgagaaactggagatgctaaagaaacagtatgatgagaagctggca
cagaaggaggagcttcgcaagaagtctgaagagatggagctgaagctggagcgagctggg
atgctcgtgtcggggttggctggcgagaaggccagatgggaggagacagtccagggcctg
gaggaggacctgggctacctggtgggggactgtctcctggcagctgccttcctgtcctac
atgggacccttcctgaccaactaccgggatgagattgtcaaccaaatctggatcgggaag
atctgggagcttcaggttccttgctccccttctttcgccatcgataacttcctgtgcaat
cctaccaaagtccgggactggaacatccaagggttgccctcagacgccttctccactgag
aatggcatcatcgtcacccgaggcaacaggtgggcactgatgatcgaccctcaggcccag
gccctgaaatggattaagaacatggaaggaggccagggcctgaagatcatcgacctgcag
atgagcgattacctgcgaatcctagaacacgccattcactttggatacccggtgctactt
cagaacgtgcaggaatatctggaccccacactgaaccccatgctcaacaaatctgtagcc
cgaatcggtggtcggctgttgatgcgcattggcgataaggaggtggaatataataccaat
ttccgtttctacatcaccaccaagctctccaacccccactacagcccagagacctcagcc
aagaccaccatcgtcaactttgctgttaaagaacagggcctggaggcccagctgctgggc
attgtggtgcggaaggagcggcctgagctggaggagcagaaggactcactggtcatcaac
atcgcggctggtaaaaggaagctcaaggagctggaggatgagatcctgcggctgctgaat
gaggccaccggctccctgctggatgatgtgcagctggtgaacacgctgcatacctccaag
atcacagccacagaggtgactgagcagctggagaccagtgagaccacagagatcaacact
gacttggcgcgggaggcttaccgcccatgcgcccagcgggcatcaatcctgttcttcgtg
ctcaatgatatgggctgcatcgaccccatgtaccagttctcactggatgcctacatcagc
ctctttattctcagcattgacaaaagccaccgcagcaataagctggaggaccgcattgac
tacctgaatgactaccacacctacgctgtctacaggtacacctgccgtacccttttcgaa
cgccacaaactactattcagttttcatatgtgtgccaaaatcttggagacttctggcaag
ctcaacatggatgaatacaacttctttctacgtgggggtgtggtcttggatcgggagggc
caaatggacaatccatgtagtagctggcttgcagatgcctactgggataacatcacagag
ctagacaaactgaccaacttccacggactcatgaactcctttgagcagtaccctcgtgac
tggcacctgtggtataccaatgctgccccggagaaggcgatgctgccaggtgagtgggaa
aatgcctgcaatgaaatgcaacggatgctgatcgttcgctccctgcgccaggaccgcgtg
gccttctgcgtgacctccttcatcatcaccaaccttggctcccgcttcatcgagccgcct
gtgctgaatatgaagtcggtgctggaggattcaaccccacgatccccactcgtgttcatc
ctgtcccctggtgtggaccccaccagtgccctgctgcagctggcagagcacatgggcatg
gcccagcgcttccacgccctgtccctgggccagggccaggcccccatcgctgctcggctc
ctccgagagggtgtgactcagggacactgggtgttcctggcaaactgccacctgtcactg
tcttggatgcctaatctggacaagctggtggagcagctgcaggtggaggatcctcatcca
tccttccgcctctggctcagctccatcccccacccagacttccctatctcaatcttgcag
gtcagcatcaagatgaccacagagccaccaaagggcctaaaggccaacatgacacgtctt
taccaactgatgtcagaaccacagttttcccgctgctccaaacctgccaaatataagaag
ctgctgttttcactctgtttcttccactctgtgttacttgaacgcaaaaagttcctgcag
cttggctggaacatcatctatggcttcaatgactccgactttgaggtgtcagaaaacttg
ctgagcctctatctcgatgagtacgaggagacaccttgggacgcacttaagtacctcatt
gccggcatcaactatggtggacatgtcacagatgactgggaccggcgcctgctgaccacc
tacatcaatgattatttctgtgaccagtctctatcaactcccttccaccggttgtcagca
ctggagacttatttcatccccaaggatggcagcctcgcttcttacaaggaatacatcagc
ttattgcctggcatggacccccctgaggcctttggccagcaccccaatgctgatgtggcc
tctcagatcactgaggcacaaaccctctttgatactttgctttccttgcaacctcagatt
acacccaccagggctggaggccagacccgggaagagaaggtccttgagttggccgctgat
gtgaagcagaagatccctgaaatgatcgactatgaggggactcaaaaactgctagctctc
gacccctcccccctcaatgtggtccttctgcaggagatccagagatacaacacactgatg
cagaccatcctgttctcactgacagacctagagaaaggcatccagggtctcatcgtcatg
tctacaagcctggaagagattttcaattgcatctttgatgcccatgttcctccgctctgg
ggaaaggcatacccctcacaaaagccattggctgcctggacccgggacttggccatgcgt
gtggagcagtttgagctgtgggccagccgggcccggcctcctgtgatcttctggttgtct
ggtttcacctttcccactggcttcctcactgctgtgctgcagtcttcagctcgccaaaac
aacgtttcagtggacagcctctcctgggagtttatcgtttccactgtggatgacagcaac
ctagtgtatccccccaaggatggtgtctgggtccggggcctgtacctggaaggtgctggc
tgggaccggaagaactcctgcttggtggaggcagagcccatgcagcttgtctgcctcatg
cccacgatccacttccggcctgcagagagccgcaagaagagcgccaagggcatgtactcc
tgcccctgctattactatcccaaccgggcaggcagctcagaccgagcctcctttgtcatc
ggcattgacctgcggtctggggccatgacacctgatcattggatcaagaggggcactgct
ctactcatgagcctggacagctga

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