Homo sapiens (human): 149371
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Entry
149371 CDS
T01001
Symbol
EXOC8, EXO84, Exo84p, NEDMISB, SEC84
Name
(RefSeq) exocyst complex component 8
KO
K19986
exocyst complex component 8
Organism
hsa
Homo sapiens (human)
Disease
H02461
Neurodevelopmental disorder with microcephaly
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
149371 (EXOC8)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Tethering complex
Exocyst complex
149371 (EXOC8)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Exo84_C
VPS51_Exo84_N
Dor1
PH
SOS1_NGEF_PH
EXOC6_Sec15_N
Motif
Other DBs
NCBI-GeneID:
149371
NCBI-ProteinID:
NP_787072
OMIM:
615283
HGNC:
24659
Ensembl:
ENSG00000116903
UniProt:
Q8IYI6
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Position
1:complement(231332753..231337852)
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AA seq
725 aa
AA seq
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MAMAMSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRIQALAEETAQNLK
RNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLTLLPAAAAAGAAAASGG
EEGVGGAGGRDHLRGQAGFFSTPGGASRDGSGPGEEGKQRTLTTLLEKVEGCRHLLETPG
QYLVYNGDLVEYDADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYSLDGLAVVN
VKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEDTKRALSEKRRREQEEAAAPRG
PPQVTSKATNPFEDDEEEEPAVPEVEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLL
DKLNHYLEDKPSPPPVKELRAKVEERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIR
LGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFEIDFAG
TDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGDIGLDLT
FIIHALLVKDIQGALHSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMKSCGVSN
FEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEIILVAVQHVDY
SLRCEQDPEKKAFIRQNASFLYETVLPVVEKRFEEGVGKPAKQLQDLRNASRLIRVNPES
TTSVV
NT seq
2178 nt
NT seq
+upstream
nt +downstream
nt
atggcgatggcgatgtcggacagtggggcgagccgcctgcgtcggcagctggagtcaggg
ggttttgaggcgcggctgtacgtgaagcagctctcgcagcagtcggatggggaccgggac
ctccaggagcaccggcagcgcatccaggcgctggcggaggagacggcgcagaacctgaag
cgcaacgtctaccagaactaccggcagttcatagagacggcccgcgagatctcctacctg
gagagcgagatgtaccagctcagccatttgctgaccgagcagaaaagcagcctggagagc
atcccgcttacgttgctgcctgccgctgctgccgccggagccgccgccgcctctggaggg
gaggagggagtcggtggggcggggggccgagaccacctccgaggccaggccggctttttc
tccacccccgggggtgcctcccgcgacggctccggtccaggcgaggaaggaaagcagcgc
actctcaccaccctgcttgagaaggtggaaggctgcaggcatctgctggagacgccggga
cagtacttggtgtacaatggggacctagtggaatacgatgcggaccacatggcccaactg
cagcgggtgcacggctttctcatgaacgattgcttgttggtggctacctggctgcctcag
cggcgtgggatgtatcgctacaacgctctctattccctagatggtttggccgtagtcaat
gtcaaggacaacccgcccatgaaggacatgttcaagctgcttatgttccccgagagccgt
attttccaggccgaaaatgctaaaatcaaacgagagtggctggaagtgctggaggacacc
aagagggccctcagtgagaaaaggcgaagggagcaggaggaggcagcggcccctcgaggg
ccaccccaagtgacttccaaggccactaacccatttgaggatgacgaagaagaagaacca
gctgttcctgaggtagaggaagagaaggtggacctctccatggaatggatccaggagtta
cctgaagacctggatgtctgcattgcgcagagagactttgaaggggcggttgacctgctg
gataaattgaaccattacctggaagataaacctagcccacctcctgtaaaagaactaagg
gccaaagtggaggagcgagttcgacagctcactgaggtgctagttttcgaactctcccca
gatcgttccctgagaggtggtccgaaggctactcgcagagcagtttcgcaactgatccgg
ctgggccagtgcacgaaggcctgtgagctatttttgagaaacagggcagccgctgttcat
actgcaattcgtcagcttcgcatcgaaggtgccactttactctatattcataagctgtgc
catgtcttctttaccagccttctcgagactgcaagagaatttgagatcgattttgcaggc
actgacagcggctgctactctgcctttgtggtctgggcaagatcagccatgggcatgttc
gtggatgcttttagcaagcaggtgtttgatagtaaggagagcctctctacagcagctgag
tgtgtaaaagtggctaaggagcattgccagcaactgggtgatatcggactggatctcacc
ttcatcatccatgcccttctggtgaaagacatccaaggggccttgcacagttacaaagaa
atcatcattgaagccactaaacatcgcaactctgaagagatgtggaggaggatgaacttg
atgacgccagaagccctgggtaagctcaaagaagagatgaaaagttgtggggtaagtaac
tttgagcagtacacaggggatgactgctgggtgaacctaagttacacagtggttgctttc
accaaacagaccatgggcttcttggaagaggccctgaagctgtatttcccagagctgcac
atggtacttttggagagcctggtggaaatcattttggttgctgttcagcatgtggattat
agtcttcgatgtgagcaggatccagagaagaaagcttttatcagacagaatgcatccttt
ttatatgaaacagtcctccctgtggtggagaaaaggtttgaagaaggtgtggggaaacct
gccaagcaactccaagatctgaggaatgcatctagacttattcgtgtgaatcctgaaagt
acaacatcagtggtctaa
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