Homo sapiens (human): 152831
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Entry
152831 CDS
T01001
Symbol
KLB, BKL
Name
(RefSeq) klotho beta
KO
K22404
beta-klotho
Organism
hsa
Homo sapiens (human)
Pathway
hsa04714
Thermogenesis
Drug target
Fazpilodemab:
D12490
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
152831 (KLB)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
152831 (KLB)
Transporters [BR:
hsa02000
]
Other transporters
Accessory factors involved in transport [TC:
8
]
152831 (KLB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_1
Motif
Other DBs
NCBI-GeneID:
152831
NCBI-ProteinID:
NP_783864
OMIM:
611135
HGNC:
15527
Ensembl:
ENSG00000134962
UniProt:
Q86Z14
B4DYH5
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:39406930..39451533
Genome browser
AA seq
1044 aa
AA seq
DB search
MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSALILLRAVTGFSGDGRAI
WSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKN
VSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLD
ALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIH
NPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITL
GSHWIEPNRSENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEK
HEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWF
TDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFY
VDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQGQFPCDFSWGVTESVLKPESVA
SSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFA
LDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADG
WLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHA
LAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTG
DYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSR
YDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDD
RLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNK
VISSRGFPFENSSSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFSTLVLLLSIAIFQRQ
KRRKFWKAKNLQHIPLKKGKRVVS
NT seq
3135 nt
NT seq
+upstream
nt +downstream
nt
atgaagccaggctgtgcggcaggatctccagggaatgaatggattttcttcagcactgat
gaaataaccacacgctataggaatacaatgtccaacgggggattgcaaagatctgtcatc
ctgtcagcacttattctgctacgagctgttactggattctctggagatggaagagctata
tggtctaaaaatcctaattttactccggtaaatgaaagtcagctgtttctctatgacact
ttccctaaaaactttttctggggtattgggactggagcattgcaagtggaagggagttgg
aagaaggatggaaaaggaccttctatatgggatcatttcatccacacacaccttaaaaat
gtcagcagcacgaatggttccagtgacagttatatttttctggaaaaagacttatcagcc
ctggattttataggagtttctttttatcaattttcaatttcctggccaaggcttttcccc
gatggaatagtaacagttgccaacgcaaaaggtctgcagtactacagtactcttctggac
gctctagtgcttagaaacattgaacctatagttactttataccactgggatttgcctttg
gcactacaagaaaaatatggggggtggaaaaatgataccataatagatatcttcaatgac
tatgccacatactgtttccagatgtttggggaccgtgtcaaatattggattacaattcac
aacccatatctagtggcttggcatgggtatgggacaggtatgcatgcccctggagagaag
ggaaatttagcagctgtctacactgtgggacacaacttgatcaaggctcactcgaaagtt
tggcataactacaacacacatttccgcccacatcagaagggttggttatcgatcacgttg
ggatctcattggatcgagccaaaccggtcggaaaacacgatggatatattcaaatgtcaa
caatccatggtttctgtgcttggatggtttgccaaccctatccatggggatggcgactat
ccagaggggatgagaaagaagttgttctccgttctacccattttctctgaagcagagaag
catgagatgagaggcacagctgatttctttgccttttcttttggacccaacaacttcaag
cccctaaacaccatggctaaaatgggacaaaatgtttcacttaatttaagagaagcgctg
aactggattaaactggaatacaacaaccctcgaatcttgattgctgagaatggctggttc
acagacagtcgtgtgaaaacagaagacaccacggccatctacatgatgaagaatttcctc
agccaggtgcttcaagcaataaggttagatgaaatacgagtgtttggttatactgcctgg
tctctcctggatggctttgaatggcaggatgcttacaccatccgccgaggattattttat
gtggattttaacagtaaacagaaagagcggaaacctaagtcttcagcacactactacaaa
cagatcatacgagaaaatggtttttctttaaaagagtccacgccagatgtgcagggccag
tttccctgtgacttctcctggggtgtcactgaatctgttcttaagcccgagtctgtggct
tcgtccccacagttcagcgatcctcatctgtacgtgtggaacgccactggcaacagactg
ttgcaccgagtggaaggggtgaggctgaaaacacgacccgctcaatgcacagattttgta
aacatcaaaaaacaacttgagatgttggcaagaatgaaagtcacccactaccggtttgct
ctggattgggcctcggtccttcccactggcaacctgtccgcggtgaaccgacaggccctg
aggtactacaggtgcgtggtcagtgaggggctgaagcttggcatctccgcgatggtcacc
ctgtattatccgacccacgcccacctaggcctccccgagcctctgttgcatgccgacggg
tggctgaacccatcgacggccgaggccttccaggcctacgctgggctgtgcttccaggag
ctgggggacctggtgaagctctggatcaccatcaacgagcctaaccggctaagtgacatc
tacaaccgctctggcaacgacacctacggggcggcgcacaacctgctggtggcccacgcc
ctggcctggcgcctctacgaccggcagttcaggccctcacagcgcggggccgtgtcgctg
tcgctgcacgcggactgggcggaacccgccaacccctatgctgactcgcactggagggcg
gccgagcgcttcctgcagttcgagatcgcctggttcgccgagccgctcttcaagaccggg
gactaccccgcggccatgagggaatacattgcctccaagcaccgacgggggctttccagc
tcggccctgccgcgcctcaccgaggccgaaaggaggctgctcaagggcacggtcgacttc
tgcgcgctcaaccacttcaccactaggttcgtgatgcacgagcagctggccggcagccgc
tacgactcggacagggacatccagtttctgcaggacatcacccgcctgagctcccccacg
cgcctggctgtgattccctggggggtgcgcaagctgctgcggtgggtccggaggaactac
ggcgacatggacatttacatcaccgccagtggcatcgacgaccaggctctggaggatgac
cggctccggaagtactacctagggaagtaccttcaggaggtgctgaaagcatacctgatt
gataaagtcagaatcaaaggctattatgcattcaaactggctgaagagaaatctaaaccc
agatttggattcttcacatctgattttaaagctaaatcctcaatacaattttacaacaaa
gtgatcagcagcaggggcttcccttttgagaacagtagttctagatgcagtcagacccaa
gaaaatacagagtgcactgtctgcttattccttgtgcagaagaaaccactgatattcctg
ggttgttgcttcttctccaccctggttctactcttatcaattgccatttttcaaaggcag
aagagaagaaagttttggaaagcaaaaaacttacaacacataccattaaagaaaggcaag
agagttgttagctaa
DBGET
integrated database retrieval system
