Homo sapiens (human): 154197
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Entry
154197 CDS
T01001
Symbol
PNLDC1, HsPNLDC1, SPGF57, Trimmer
Name
(RefSeq) PARN like ribonuclease domain containing exonuclease 1
KO
K01148
poly(A)-specific ribonuclease [EC:
3.1.13.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03018
RNA degradation
Disease
H01282
Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
154197 (PNLDC1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
154197 (PNLDC1)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.13 Exoribonucleases producing 5'-phosphomonoesters
3.1.13.4 poly(A)-specific ribonuclease
154197 (PNLDC1)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Other 3'-5' decay factors
154197 (PNLDC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CAF1
Motif
Other DBs
NCBI-GeneID:
154197
NCBI-ProteinID:
NP_775787
OMIM:
619529
HGNC:
21185
Ensembl:
ENSG00000146453
UniProt:
Q8NA58
LinkDB
All DBs
Position
6:159799455..159820704
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AA seq
520 aa
AA seq
DB search
MFCTRGLLFFAFLAGLDIEFTGLRSNLSGPQQISLFDLPSEWYLKTRQSVQQFTVCQIGL
SVFSAIEGEANKYIAHSCNFYLFPTTFGILDSEFSFQASSVQFLNQYGFNYNKFLKNGIP
YMNEEQEKKIRHDILTGNWRVRSSPDKDQIKVVIDEVTRWLELAKEGDWMTLPGITGFQA
FEVQLVLRQALPNIWTVLKDEGVVVKKVSKQHRWYLQNTSCDRESCWKENILLSARGFSV
FFQMLVKAQKPLVGHNMMMDLLHLHEKFFRPLPESYDQFKQNIHSLFPVLIDTKSVTKDI
WKEMNFPRVSNLSEVYEVLNSDLNPTKNSGPEIVHASRCEKYVETKCPHEAAYDAFLCGS
VLLKVAHLLLQKIYHIDPVPESSFPQYLDVLAPYVNQVNLIRAGVPKINFSGPDYPSIRP
PILILSVKRWPGVSEQQVYHKFQNLCKFDVRRLTRSQFLLLTNKFKDARNILKEYRDHPT
LCISLYRYWRHSPNVNCLLQVCGIVTAWALLAFILGRSGT
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgttctgcacccgaggactgctattttttgccttcctggcaggtctggacatagagttc
acgggccttcgttctaacctgtctgggccccagcagatcagtctttttgatttgccatcg
gagtggtatctaaagacccgtcagagtgttcagcaatttacagtctgtcagattggattg
tctgtgttttccgctattgaaggagaggcaaacaagtatatagcccattcttgtaacttc
tatctcttccctacaacgtttgggattttggactcagaattctccttccaggcttccagt
gttcagtttttgaatcagtatggcttcaactataacaagtttctcaaaaacggaatccca
tatatgaatgaagaacaggagaagaaaattagacacgatatcctgactgggaactggaga
gttcgcagctctccggataaagaccaaatcaaggtggtgattgacgaagtgacgcggtgg
ctggagctggccaaggaaggcgactggatgactcttcctgggatcactggcttccaggcc
tttgaggtccaactggtgctgaggcaggccctccccaacatctggacggtgctgaaagat
gagggggtggtagtgaagaaagtgagtaaacaacatcgttggtatcttcagaacacctct
tgtgaccgagagagctgttggaaggaaaatattcttctctcagcaaggggtttttctgtc
tttttccaaatgctggtgaaagcccagaagcccttagtgggacataatatgatgatggac
ctgctgcacctccatgagaagttcttcagacccctcccagaaagctacgatcaatttaag
cagaatatccacagcctatttcctgttctcattgataccaagagtgtaacaaaggatatc
tggaaggagatgaatttcccgagggtgtcgaatctttcggaagtctatgaagtcctgaac
agtgacttgaatcccaccaagaattctggaccagagattgttcacgcgagcaggtgtgag
aaatatgttgagacaaagtgcccccacgaagccgcgtatgatgccttcctctgtgggtca
gttcttttgaaagtggcacacttgcttctacagaagatataccacatcgaccccgtgccc
gagtcatcctttcctcagtaccttgacgtgctggctccttacgtgaaccaagtgaacctc
atccgagcgggggtcccaaagatcaatttttctggtccagattatcccagtatccgacct
cccatcctcatcctcagcgtcaaaaggtggcctggggtcagcgagcagcaagtctaccat
aagtttcagaatctctgcaagtttgatgtcaggcgactcacaagaagccagttcttactc
ctgaccaataagtttaaggatgcgcggaacatcctgaaggagtaccgggaccacccgacc
ctgtgcatctccctgtaccgctactggaggcactccccaaacgtcaactgcctgctccaa
gtctgtggcatagtgactgcctgggcccttctcgcgttcatccttggaagatctggtacc
tga
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