Homo sapiens (human): 156
Help
Entry
156 CDS
T01001
Symbol
GRK2, ADRBK1, BARK1, BETA-ARK1
Name
(RefSeq) G protein-coupled receptor kinase 2
KO
K00910
beta-adrenergic-receptor kinase [EC:
2.7.11.15
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
hsa04144
Endocytosis
hsa04340
Hedgehog signaling pathway
hsa04724
Glutamatergic synapse
hsa04740
Olfactory transduction
hsa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
156 (GRK2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
156 (GRK2)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
156 (GRK2)
09156 Nervous system
04724 Glutamatergic synapse
156 (GRK2)
09157 Sensory system
04740 Olfactory transduction
156 (GRK2)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
156 (GRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
156 (GRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
156 (GRK2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.15 beta-adrenergic-receptor kinase
156 (GRK2)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
156 (GRK2)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
156 (GRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
PH
Kinase-like
Haspin_kinase
DUF5647
HTH_WhiA
Motif
Other DBs
NCBI-GeneID:
156
NCBI-ProteinID:
NP_001610
OMIM:
109635
HGNC:
289
Ensembl:
ENSG00000173020
UniProt:
P25098
A0A0S2Z392
Structure
PDB
PDBj
LinkDB
All DBs
Position
11:67266473..67286556
Genome browser
AA seq
689 aa
AA seq
DB search
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC
SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLVQRGSANGL
NT seq
2070 nt
NT seq
+upstream
nt +downstream
nt
atggcggacctggaggcggtgctggccgacgtgagctacctgatggccatggagaagagc
aaggccacgccggccgcgcgcgccagcaagaagatcctgctgcccgagcccagcatccgc
agtgtcatgcagaagtacctggaggaccggggcgaggtgacctttgagaagatcttttcc
cagaagctggggtacctgctcttccgagacttctgcctgaaccacctggaggaggccagg
cccttggtggaattctatgaggagatcaagaagtacgagaagctggagacggaggaggag
cgtgtggcccgcagccgggagatcttcgactcatacatcatgaaggagctgctggcctgc
tcgcatcccttctcgaagagtgccactgagcatgtccaaggccacctggggaagaagcag
gtgcctccggatctcttccagccatacatcgaagagatttgtcaaaacctccgaggggac
gtgttccagaaattcattgagagcgataagttcacacggttttgccagtggaagaatgtg
gagctcaacatccacctgaccatgaatgacttcagcgtgcatcgcatcattgggcgcggg
ggctttggcgaggtctatgggtgccggaaggctgacacaggcaagatgtacgccatgaag
tgcctggacaaaaagcgcatcaagatgaagcagggggagaccctggccctgaacgagcgc
atcatgctctcgctcgtcagcactggggactgcccattcattgtctgcatgtcatacgcg
ttccacacgccagacaagctcagcttcatcctggacctcatgaacggtggggacctgcac
taccacctctcccagcacggggtcttctcagaggctgacatgcgcttctatgcggccgag
atcatcctgggcctggagcacatgcacaaccgcttcgtggtctaccgggacctgaagcca
gccaacatccttctggacgagcatggccacgtgcggatctcggacctgggcctggcctgt
gacttctccaagaagaagccccatgccagcgtgggcacccacgggtacatggctccggag
gtcctgcagaagggcgtggcctacgacagcagtgccgactggttctctctggggtgcatg
ctcttcaagttgctgcgggggcacagccccttccggcagcacaagaccaaagacaagcat
gagatcgaccgcatgacgctgacgatggccgtggagctgcccgactccttctcccctgaa
ctacgctccctgctggaggggttgctgcagagggatgtcaaccggagattgggctgcctg
ggccgaggggctcaggaggtgaaagagagcccctttttccgctccctggactggcagatg
gtcttcttgcagaagtaccctcccccgctgatccccccacgaggggaggtgaacgcggcc
gacgccttcgacattggctccttcgatgaggaggacacaaaaggaatcaagttactggac
agtgatcaggagctctaccgcaacttccccctcaccatctcggagcggtggcagcaggag
gtggcagagactgtcttcgacaccatcaacgctgagacagaccggctggaggctcgcaag
aaagccaagaacaagcagctgggccatgaggaagactacgccctgggcaaggactgcatc
atgcatggctacatgtccaagatgggcaaccccttcctgacccagtggcagcggcggtac
ttctacctgttccccaaccgcctcgagtggcggggcgagggcgaggccccgcagagcctg
ctgaccatggaggagatccagtcggtggaggagacgcagatcaaggagcgcaagtgcctg
ctcctcaagatccgcggtgggaaacagttcattttgcagtgcgatagcgaccctgagctg
gtgcagtggaagaaggagctgcgcgacgcctaccgcgaggcccagcagctggtgcagcgg
gtgcccaagatgaagaacaagccgcgctcgcccgtggtggagctgagcaaggtgccgctg
gtccagcgcggcagtgccaacggcctctga
Homo sapiens (human): 157
Help
Entry
157 CDS
T01001
Symbol
GRK3, ADRBK2, BARK2
Name
(RefSeq) G protein-coupled receptor kinase 3
KO
K00910
beta-adrenergic-receptor kinase [EC:
2.7.11.15
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
hsa04144
Endocytosis
hsa04340
Hedgehog signaling pathway
hsa04724
Glutamatergic synapse
hsa04740
Olfactory transduction
hsa05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04340 Hedgehog signaling pathway
157 (GRK3)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
157 (GRK3)
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
157 (GRK3)
09156 Nervous system
04724 Glutamatergic synapse
157 (GRK3)
09157 Sensory system
04740 Olfactory transduction
157 (GRK3)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
157 (GRK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
157 (GRK3)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
157 (GRK3)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.15 beta-adrenergic-receptor kinase
157 (GRK3)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
GRK family [OT]
157 (GRK3)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
157 (GRK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RGS
PH
HTH_WhiA
Kinase-like
Motif
Other DBs
NCBI-GeneID:
157
NCBI-ProteinID:
NP_005151
OMIM:
109636
HGNC:
290
Ensembl:
ENSG00000100077
UniProt:
P35626
Q8N433
LinkDB
All DBs
Position
22:25564675..25729294
Genome browser
AA seq
688 aa
AA seq
DB search
MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN
QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC
SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV
ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE
IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE
LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK
RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL
LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR
APKFLNKPRSGTVELPKPSLCHRNSNGL
NT seq
2067 nt
NT seq
+upstream
nt +downstream
nt
atggcggacctggaggctgtgctggccgatgtcagttacctgatggccatggagaagagc
aaggcgaccccggccgcccgcgccagcaagaggatcgtcctgccggagcccagtatccgg
agtgtgatgcagaagtaccttgcagagagaaatgaaataacctttgacaagattttcaat
cagaaaattggtttcttgctatttaaagatttttgtttgaatgaaattaatgaagctgta
cctcaggtgaagttttatgaagagataaaggaatatgaaaaacttgataatgaggaagac
cgcctttgcagaagtcgacaaatttatgatgcctacatcatgaaggaacttctttcctgt
tcacatcctttctcaaagcaagctgtagaacacgtacaaagtcatttatccaagaaacaa
gtgacatcaactctttttcagccatacatagaagaaatttgtgaaagccttcgaggtgac
atttttcaaaaatttatggaaagtgacaagttcactagattttgtcagtggaaaaacgtt
gaattaaatatccatttgaccatgaatgagttcagtgtgcataggattattggacgagga
ggattcggggaagtttatggttgcaggaaagcagacactggaaaaatgtatgcaatgaaa
tgcttagataagaagaggatcaaaatgaaacaaggagaaacattagccttaaatgaaaga
atcatgttgtctcttgtcagcacaggagactgtcctttcattgtatgtatgacctatgcc
ttccataccccagataaactctgcttcatcctggatctgatgaacgggggcgatttgcac
taccacctttcacaacacggtgtgttctctgagaaggagatgcggttttatgccactgaa
atcattctgggtctggaacacatgcacaatcggtttgttgtctacagagatttgaagcca
gcaaatattctcttggatgaacatggacacgcaagaatatcagatcttggtcttgcctgc
gatttttccaaaaagaagcctcatgcgagtgttggcacccatgggtacatggctcccgag
gtgctgcagaaggggacggcctatgacagcagtgccgactggttctccctgggctgcatg
cttttcaaacttctgagaggtcacagccctttcagacaacataaaaccaaagacaagcat
gaaattgaccgaatgacactcaccgtgaatgtggaacttccagacaccttctctcctgaa
ctgaagtcccttttggagggcttgcttcagcgagacgttagcaagcggctgggctgtcac
ggaggcggctcacaggaagtaaaagagcacagctttttcaaaggtgttgactggcagcat
gtctacttacaaaagtacccaccacccttgattcctccccggggagaagtcaatgctgct
gatgcctttgatattggctcatttgatgaagaggataccaaagggattaagctacttgat
tgcgaccaagaactctacaagaacttccctttggtcatctctgaacgctggcagcaagaa
gtaacggaaacagtttatgaagcagtaaatgcagacacagataaaatcgaggccaggaag
agagctaaaaataagcaacttggccacgaagaagattacgctctggggaaggactgtatt
atgcacgggtacatgctgaaactgggaaacccatttctgactcagtggcagcgtcgctat
ttttacctctttccaaatagacttgaatggagaggagagggagagtcccggcaaaattta
ctgacaatggaacagattctctctgtggaagaaactcaaattaaagacaaaaaatgcatt
ttgttcagaataaaaggagggaaacaatttgtcttgcaatgtgagagtgatccagagttt
gtgcagtggaagaaagagttgaacgaaaccttcaaggaggcccagcggctattgcgtcgt
gccccgaagttcctcaacaaacctcggtcaggtactgtggagctcccaaagccatccctc
tgtcacagaaacagcaacggcctctag
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integrated database retrieval system
