Homo sapiens (human): 157855
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Entry
157855 CDS
T01001
Symbol
KCNU1, KCNMC1, KCa5, KCa5.1, Kcnma3, SPGF79, Slo3
Name
(RefSeq) potassium calcium-activated channel subfamily U member 1
KO
K05274
potassium large conductance calcium-activated channel subfamily M alpha member 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04022
cGMP-PKG signaling pathway
hsa04270
Vascular smooth muscle contraction
hsa04911
Insulin secretion
Disease
H01282
Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
157855 (KCNU1)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
157855 (KCNU1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
157855 (KCNU1)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Potassium channel, calcium- and sodium-activated (KCa/KNa)
157855 (KCNU1)
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Slo-like_RCK
Slowpoke_C
BK_channel_a
Ion_trans
Ion_trans_2
DUF6609
Motif
Other DBs
NCBI-GeneID:
157855
NCBI-ProteinID:
NP_001027006
OMIM:
615215
HGNC:
18867
Ensembl:
ENSG00000215262
UniProt:
A8MYU2
Structure
PDB
PDBj
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All DBs
Position
8:36784374..36936125
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AA seq
1149 aa
AA seq
DB search
MFQTKLRNETWEDLPKMSCTTEIQAAFILSSFVTFFSGLIILLIFRLIWRSVKKWQIIKG
TGIILELFTSGTIARSHVRSLHFQGQFRDHIEMLLSAQTFVGQVLVILVFVLSIGSLIIY
FINSADPVGSCSSYEDKTIPIDLVFNAFFSFYFGLRFMAADDKIKFWLEMNSIVDIFTIP
PTFISYYLKSNWLGLRFLRALRLLELPQILQILRAIKTSNSVKFSKLLSIILSTWFTAAG
FIHLVENSGDPWLKGRNSQNISYFESIYLVMATTSTVGFGDVVAKTSLGRTFIMFFTLGS
LILFANYIPEMVELFANKRKYTSSYEALKGKKFIVVCGNITVDSVTAFLRNFLRDKSGEI
NTEIVFLGETPPSLELETIFKCYLAYTTFISGSAMKWEDLRRVAVESAEACLIIANPLCS
DSHAEDISNIMRVLSIKNYDSTTRIIIQILQSHNKVYLPKIPSWNWDTGDNIICFAELKL
GFIAQGCLVPGLCTFLTSLFVEQNKKVMPKQTWKKHFLNSMKNKILTQRLSDDFAGMSFP
EVARLCFLKMHLLLIAIEYKSLFTDGFCGLILNPPPQVRIRKNTLGFFIAETPKDVRRAL
FYCSVCHDDVFIPELITNCGCKSRSRQHITVPSVKRMKKCLKGISSRISGQDSPPRVSAS
TSSISNFTTRTLQHDVEQDSDQLDSSGMFHWCKPTSLDKVTLKRTGKSKYKFRNHIVACV
FGDAHSAPMGLRNFVMPLRASNYTRKELKDIVFIGSLDYLQREWRFLWNFPQIYILPGCA
LYSGDLHAANIEQCSMCAVLSPPPQPSSNQTLVDTEAIMATLTIGSLQIDSSSDPSPSVS
EETPGYTNGHNEKSNCRKVPILTELKNPSNIHFIEQLGGLEGSLQETNLHLSTAFSTGTV
FSGSFLDSLLATAFYNYHVLELLQMLVTGGVSSQLEQHLDKDKVYGVADSCTSLLSGRNR
CKLGLLSLHETILSDVNPRNTFGQLFCGSLDLFGILCVGLYRIIDEEELNPENKRFVITR
PANEFKLLPSDLVFCAIPFSTACYKRNEEFSLQKSYEIVNKASQTTETHSDTNCPPTIDS
VTETLYSPVYSYQPRTNSLSFPKQIAWNQSRTNSIISSQIPLGDNAKENERKTSDEVYDE
DPFAYSEPL
NT seq
3450 nt
NT seq
+upstream
nt +downstream
nt
atgtttcagactaagctacgaaatgaaacttgggaagacttgccaaaaatgtcctgcaca
actgagatccaagcagcattcattctctcttcctttgtgaccttcttcagtggactcatc
atcctgttgatcttcaggctgatctggagatctgttaaaaaatggcaaatcatcaaggga
acaggaattatcttggaactgttcacatcaggtaccatcgctaggagccatgtaagaagc
ctccacttccagggacaatttcgtgatcatatagaaatgttgctttcagcccagaccttt
gtggggcaagtgttggtgatccttgtctttgtactaagcattgggtctcttataatctat
ttcatcaattctgctgaccctgttggaagctgttcatcatatgaagacaaaaccattcct
attgatttggttttcaatgctttctttagtttctattttggattgaggtttatggcagct
gatgacaagatcaagttctggctggagatgaattcaatcgtagacatctttaccatccca
ccaacctttatttcttattatttgaagagcaattggctaggtttaaggttcctaagagcc
ttgcgcctgctagaactccctcaaatcttgcaaattctacgagccatcaagaccagtaac
tcagtgaagttttccaaactgctgtcaataattctcagtacctggttcacagctgcggga
ttcattcacctggtggaaaattctggtgatccctggctcaaaggtagaaattcacagaat
atatcatattttgagtcaatttacctggtcatggcaacaacgtcaaccgttggatttgga
gatgtggtagccaagacatccttaggacggaccttcatcatgttcttcacactggggagt
ttgatattatttgcgaactatatacctgaaatggtggaactgtttgctaacaagaggaaa
tacaccagttcctatgaagcactcaaaggaaagaagtttattgtggtctgtggaaacatc
actgtggacagtgtgaccgctttcctgaggaatttcctccgcgacaagtcaggagagatc
aacactgaaattgttttcctgggagaaacccctccttctttggaacttgaaaccatattt
aaatgctacttggcctacacaacgttcatttctggatctgcaatgaagtgggaggatctg
aggcgagttgcggtggaatctgcagaggcatgcctgattatagccaatcctttgtgcagt
gattcccatgctgaagatatttccaacattatgagggtgctctctatcaagaactatgat
tctaccaccagaatcatcatacagatactgcaatcccataacaaggtttatctgccaaag
attcccagctggaactgggacaccggagacaacatcatctgctttgctgaattaaaactt
ggatttatcgcccaaggctgtttggtgccaggcttgtgtaccttcctaacatctctattt
gtggagcaaaacaaaaaggttatgcctaaacagacctggaagaaacacttcttgaatagc
atgaaaaacaaaattctgacccaacgtctctctgatgactttgctggaatgagctttcct
gaagttgcccggctctgctttctgaagatgcacctcctgttgatagccatcgaatacaag
tccctctttacggatggtttctgtggtctgatactaaatccacctccacaagtgaggata
cgtaagaacacattagggttctttattgctgaaactccaaaggacgtcagaagagccttg
ttttactgttcagtctgtcatgatgatgtgttcattcctgagctaattacaaactgtggc
tgcaaaagcagaagccggcagcacatcacagtgccatcggtaaagagaatgaaaaaatgt
ctgaagggaatctcctctcgtatatcagggcaggattctccgccaagggtatctgcaagc
acttcgagcatatcaaacttcaccaccaggactcttcaacatgatgtagaacaagattct
gaccagcttgatagcagtgggatgtttcactggtgcaaaccaacctctttggacaaggtg
actctgaaacgaactggcaagtcaaagtataagtttcggaaccatattgtagcatgtgta
tttggagatgcccactcagccccgatggggcttcggaactttgtaatgcccttgagagcc
agcaactataccaggaaggagctgaaggacatagtgttcattgggtctctggactatcta
cagagagaatggcgatttctctggaattttccccagatatacattctgcctggatgtgca
ctttattctggagacctccatgcggccaacatagagcaatgctccatgtgtgctgtcttg
tcccccccaccccagccatcaagcaaccagactttggtagacacagaagccatcatggca
accctcaccatcggatccttgcaaattgactcctcctctgacccgtcaccctcagtgtca
gaggagactccaggttacacaaatggacataatgagaaatcaaactgccgaaaagtccct
atccttactgaactgaaaaatccttccaacattcactttattgaacagcttggtggactg
gaagggtccctccaagaaacaaatctgcatctcagcactgccttttctacgggcactgtt
ttttccggcagcttcttggattctctgctggccacggccttctacaattatcatgtcctg
gaattgcttcagatgctggtgacaggaggagtaagttctcagctggaacaacatttagat
aaggataaagtctatggtgtggcagatagctgcacgtcgctcttgtctggaagaaaccgg
tgtaagctggggcttctgtccttacacgaaaccattttatcagacgttaatccaagaaac
acctttggacaactgttctgtggctcattagatctttttggaatcctgtgtgttggctta
taccgaataattgatgaagaggagctcaacccagaaaacaaaaggtttgtgatcacccgg
ccagccaatgagttcaagctgctgccttcagatcttgtgttttgtgccatacccttcagc
actgcttgttataaaaggaatgaagagttctcattgcaaaagtcatatgaaattgtaaat
aaagcatcacagacaacagagacacattcagacacaaattgtcctcccaccattgattca
gttactgagacattgtattcaccagtctattcttaccagccgagaactaactccctctct
tttcctaagcaaatagcatggaatcagagtagaacaaacagtattatatcatctcagata
cctttaggtgacaatgcaaaagaaaatgaaaggaaaacttcagatgaggtttatgatgag
gatccctttgcatattcagagccactatag
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integrated database retrieval system
